1_Events

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

Introduction of Antonio Martinez-Sanchez as new MBExC member
Tiago Outerio “Overview RA 2.2”
Tim Salditt „Multi-scale x-ray imaging form cardiomyocyte to the heart“
Sarah Köster „Studying vimentin assembly by fluorescence fluctuation spectroscopy“

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

Chair: Peter Rehling

Introduction of Housen Li as new MBExC member
Ricarda Richter-Dennerlein “Mitochondrial gene expression – Ribosome biogenesis in human mitochondria”
Hauke Hillen „Transcription in human mitochondria“
Stefan Stoldt „Sub-mitochondrial localization of gene expression“

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

Chair: Ruben Fernandez-Busnadiego

Introduction of Tat Cheng as new MBExC member
Ruben Fernandez-Busnadiego “Overview RA 2.1”
Evelina DeLaurentiis „Membrane protein targeting from the ribosome to the GET pathway“

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

Chair: Claudia Steinem

Introduction of Thomas Mager as new MBExC member
Claudia Steinem “Overview RA 3.1”
Alexey Chizhik „Advanced high-resolution and single-molecule fluorescence microscopy“

Tobias Kohl „Evidence for cluster dynamics inside CRUs“

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

HSC-Workshop Advanced Data Analysis: From a Natural Science Perspective

Supervisor: Dr. Housen Li

Chair: Tobias Moser

Dr. Rahul Kaushik “Regulations of synaptic changes: relevance to brain physiology and pathology”

Introduction into Electron Microscopy (beginner Level)

Workshop: 16. September / 23. September  / 30. September 2020

Supervisor: Dr. Tat Cheng

Introduction into Electron Microscopy (beginner Level)

Workshop: 16. September / 23. September  / 30. September 2020

Supervisor: Dr. Tat Cheng

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Wednesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to meet the PI and each other for asking more specific or general questions, networking and socializing.

Presentation Series of Research Alliance 1.1 “Mitochondrial Gene Expression”

23. September: “Mitochondrial Protein Biogenesis”, Prof. Peter Rehling, Department of Cellular Biochemistry, UMG

07. October: (ggf. 30 min later) “Engineering Networks of Excitable Cells: from Cell to Tissue”, Prof. Dr. Wolfram-Hubertus Zimmermann, Institute of Pharmacology and Toxicology, UMG

28. October: Prof. Dr. Bernd Wollnik, Institute of Human Genetics, UMG

11. November: Prof. Dr. Gerd Hasenfuß, Department of Cardiology and Pneumology, UMG

25. November: “How to measure “colocalization”?”, Prof. Dr. Axel Munk, Institute for Mathematical Stochastics, UG  

09. December: Prof. Dr. Helmut Grubmüller, Department of Theoretical and Computational Biophysics, MPIbpc

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Introduction into Electron Microscopy (beginner Level)

Workshop: 16. September / 23. September  / 30. September 2020

Supervisor: Dr. Tat Cheng

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Wednesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to meet the PI and each other for asking more specific or general questions, networking and socializing.

Presentation Series of Research Alliance 1.1 “Mitochondrial Gene Expression”

23. September: “Mitochondrial Protein Biogenesis”, Prof. Peter Rehling, Department of Cellular Biochemistry, UMG

07. October: (30 min later) “Engineering Networks of Excitable Cells: from Cell to Tissue”, Prof. Dr. Wolfram-Hubertus Zimmermann, Institute of Pharmacology and Toxicology, UMG

28. October: Prof. Dr. Bernd Wollnik, Institute of Human Genetics, UMG

11. November: “From the patient to the bench and back – Development of a new molecular approach to treat patients with aortic stenosis”, Prof. Dr. Gerd Hasenfuß, Department of Cardiology and Pneumology, UMG

25. November: “How to measure “colocalization”?”, Prof. Dr. Axel Munk, Institute for Mathematical Stochastics, UG  

09. December: Prof. Dr. Helmut Grubmüller, Department of Theoretical and Computational Biophysics, MPIbpc

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Chair: Tobias Moser

Prof. Dr. Timo Betz “Deciphering the role of active mechanics in cell biology, development and disease”

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Wednesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to meet the PI and each other for asking more specific or general questions, networking and socializing.

Presentation Series of Research Alliance 1.1 “Mitochondrial Gene Expression”

23. September: “Mitochondrial Protein Biogenesis”, Prof. Peter Rehling, Department of Cellular Biochemistry, UMG

07. October: (30 min later) “Engineering Networks of Excitable Cells: from Cell to Tissue”, Prof. Dr. Wolfram-Hubertus Zimmermann, Institute of Pharmacology and Toxicology, UMG

28. October: “Novel genes and mechanisms associated with accelerated ageing phenotypes”, Prof. Dr. Bernd Wollnik, Institute of Human Genetics, UMG

11. November: “From the patient to the bench and back – Development of a new molecular approach to treat patients with aortic stenosis”, Prof. Dr. Gerd Hasenfuß, Department of Cardiology and Pneumology, UMG

25. November: “How to measure “colocalization”?”, Prof. Dr. Axel Munk, Institute for Mathematical Stochastics, UG  

09. December: “Nanomachines at Work: Atomistic Simulations of Biomolecular Systems”,” Prof. Dr. Helmut Grubmüller, Department of Theoretical and Computational Biophysics, MPIbpc

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Chair: Tobias Moser

Prof. Dr. Jörg Striessnig “Cav1.3 L-type calcium channels in human disease: beyond deafness”

Elementary Course on Basic Statistical Methods

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Exercises: Thursdays, 10:15 – 11:15 am (Start: 05. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Hertha Sponer College Small Group Seminar

“Research Data Management within MBExC: an overview”

MBExC Data Manager Dr. Harald Kusch, Institute for Medical Informatics, UMG

Elementary Course on Basic Statistical Methods

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Exercises: Thursdays, 10:15 – 11:15 am (Start: 05. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Wednesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to meet the PI and each other for asking more specific or general questions, networking and socializing.

Presentation Series of Research Alliance 1.1 “Mitochondrial Gene Expression”

23. September: “Mitochondrial Protein Biogenesis”, Prof. Peter Rehling, Department of Cellular Biochemistry, UMG

07. October: (30 min later) “Engineering Networks of Excitable Cells: from Cell to Tissue”, Prof. Dr. Wolfram-Hubertus Zimmermann, Institute of Pharmacology and Toxicology, UMG

28. October: “Novel genes and mechanisms associated with accelerated ageing phenotypes”, Prof. Dr. Bernd Wollnik, Institute of Human Genetics, UMG

11. November: “From the patient to the bench and back – Development of a new molecular approach to treat patients with aortic stenosis”, Prof. Dr. Gerd Hasenfuß, Department of Cardiology and Pneumology, UMG

25. November: “How to measure “colocalization”?”, Prof. Dr. Axel Munk, Institute for Mathematical Stochastics, UG  

09. December: “Nanomachines at Work: Atomistic Simulations of Biomolecular Systems”, Prof. Dr. Helmut Grubmüller, Department of Theoretical and Computational Biophysics, MPIbpc

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Exercises: Thursdays, 10:15 – 11:15 am (Start: 05. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Exercises: Thursdays, 10:15 – 11:15 am (Start: 05. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Hertha Sponer College Small Group Seminar

“Brain and heart in a dish – modeling human organogenesis”

Seminar in preparation of the upcoming Advanced Methods Courses

Dr. Maria-Patapia Zafeiriou, Institut of Pharmacology and Toxicology, UMG

Elementary Course on Basic Statistical Methods

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Exercises: Thursdays, 10:15 – 11:15 am (Start: 05. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Chair: Tobias Moser

Dr. Dr. Oliver Schlüter “Synaptic states, their plasticity and implications for psychiatric disorders”

Hertha Sponer College Small Group Seminar

Grantmanship – Stepping Stones to Foster Your Ideas, Career and Independence

Prof. Dr. Stephan E. Lehnart, Heart Center Göttingen, UMG & Dr. Heike Conrad, MBExC

Elementary Course on Basic Statistical Methods

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Exercises: Thursdays, 10:15 – 11:15 am (Start: 05. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Wednesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to meet the PI and each other for asking more specific or general questions, networking and socializing.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Exercises: Thursdays, 10:15 – 11:15 am (Start: 05. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Wednesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to meet the PI and each other for asking more specific or general questions, networking and socializing.

Presentation Series of Research Alliance 1.1 “Mitochondrial Gene Expression”

23. September: “Mitochondrial Protein Biogenesis”, Prof. Peter Rehling, Department of Cellular Biochemistry, UMG

07. October: (30 min later) “Engineering Networks of Excitable Cells: from Cell to Tissue”, Prof. Dr. Wolfram-Hubertus Zimmermann, Institute of Pharmacology and Toxicology, UMG

28. October: “Novel genes and mechanisms associated with accelerated ageing phenotypes”, Prof. Dr. Bernd Wollnik, Institute of Human Genetics, UMG

11. November: “From the patient to the bench and back – Development of a new molecular approach to treat patients with aortic stenosis”, Prof. Dr. Gerd Hasenfuß, Department of Cardiology and Pneumology, UMG

postponed to January 26th, 2021 (25. November): “How to measure “colocalization”?”, Prof. Dr. Axel Munk, Institute for Mathematical Stochastics, UG

09. December: “Nanomachines at Work: Atomistic Simulations of Biomolecular Systems”, Prof. Dr. Helmut Grubmüller, Department of Theoretical and Computational Biophysics, MPIbpc

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

Elementary Course on Basic Statistical Methods 

This lecture series intends to serve as an introduction to statistical data analysis, with emphasis on the data analysis methods that are useful in labs related to the MBExC Cluster of Excellence. Topics will cover statistical paradoxes, graphical methods (including histograms, box plot, Q-Q plots, etc.), basic stat theory (e.g. multivariate normal distribution, Bayes theorem), regression, categorical data analysis, censoring and survival analysis. The required basic knowledge will also be provided in the lecture. Further topics, such as testing, ANOVA, time series, MCMC, clustering and classifications, etc. will be provided in a follow-up lecture series.

Continuous weekly lecture & exercises over 12 weeks:

Lectures: Wednesdays, 10:15 – 11:45 am (Start: 04. November 2020)

Supervisor: Dr. Housen Li, Institute of Mathematical Stochastics, UG

During the virtual MBExC retreat on March 8th and 9th, 2021 the results of the research will be exchanged and discussed.
This years retreat will address the more vertical topics of the MBExC rather then the classical lines of research with focus on:
-Bioimaging: experimental, computational and theoretical approaches
-Bridging time and length scales of functional organization
-Cardiac and neural networks of excitable cells

The programme of talks will be accompanied by two workshops and virtual poster sessions.

Another highlight will be the keynote talk, which will be held by Jan Huisken from the Morgridge Institute for Research, Madison WI, USA on Tuesday, March 9th and is titled “Light sheet microscopy across scales in live and fixed tissues“.

Click here for the MBExC retreat programme 2021

During the virtual MBExC retreat on March 8th and 9th, 2021 the results of the research will be exchanged and discussed.
This years retreat will address the more vertical topics of the MBExC rather then the classical lines of research with focus on:
-Bioimaging: experimental, computational and theoretical approaches
-Bridging time and length scales of functional organization
-Cardiac and neural networks of excitable cells

The programme of talks will be accompanied by two workshops and virtual poster sessions.

Another highlight will be the keynote talk, which will be held by Jan Huisken from the Morgridge Institute for Research, Madison WI, USA on Tuesday, March 9th and is titled “Light sheet microscopy across scales in live and fixed tissues“.

Click here for the MBExC retreat programme 2021

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Thursday, March 25, 2021

3:00 PM Musical prelude by Empire Wild, Q&A session with the musicians

4:00 PM Tobias Moser (University Medical Center Göttingen, Germany)
“Mechanisms of sound intensity encoding: what heterogeneous afferent synapses and neurons are good for”

5:00 PM Katja Bleckmann (University of Oldenburg, Germany)
“Behavioral, physiological, and anatomical assessment of the hearing performance in Bl/6.CAST mice missing the glutathione peroxidase 1”

5:20 PM Ruth Anne Eatock (University of Chicago, USA)
“Seeking balance: Quantal and non-quantal transmission from vestibular hair cells to afferents”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Thursday, April 15, 2021

4:00 PM Musical prelude by Mike Weis, Q&A session with the musician

5:00 PM Fred Rieke (University of Washington, Seattle, USA)
“Synaptic nonlinearities and the coding of natural visual inputs”

6:00 PM Jeffrey N. Savas (Northwestern University Feinberg School of Medicine, Chicago, USA)
“Cochlear Proteostasis in Noise Induced Hearing Disorders”

5:20 PM M. Charles Liberman (Harvard Medical School, Boston, USA)
“Cochlear synaptopathy in noise-induced and age-related hearing loss”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

Chair: Tobias Moser and Thomas Mager

Prof. Dr. Valentin Gordeliy from the IBS, Université Grenoble Alpes, France and Jülich Center for Structural Biology, Forschungszentrum Jülich will talk about “New Rhodopsins as Potential Tools for Optogenetics”.

Abstract

We will describe recent discoveries and properties of rhodopsins which are potential candidates as next generation optogenetic tools.

Comprehensive structure-function studies of the representatives of recently characterized xenorhodopsins (XeRs), a family of microbial rhodopsins will be presented. These proteins are inward proton pumps in E.coli cells, human embryonic kidney cells, neuroblastoma cells and rat hippocampal neuronal cells. XeRs are powerful pumps which are able to elicit action potentials in rat hippocampal neuronal cells up to their maximal intrinsic firing frequency, proving that the inwardly directed proton pumps are suitable for light induced remote control of neurons and are an alternative to the well-known cation selective channelrhodopsins. Some new XeRs and their possible optogenetic applications will be also discussed. In addition, we will provide for the first time the results of structure-function studies of viral rhodopsins and discuss their potential for optogenetic applications.

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 2:  “Membrane Protein Targeting”

09 February: “Investigating the molecular architecture of cells with cryo-electron tomography”, Prof. Dr. Rubén Fernández-Busnadiego, Institute of Neuropathology, UMG

23. February: “Recent advances in super-resolutions single-molecule localization microscopy”, Prof. Dr. Jörg Enderlein, Biophysics, Third Institute of Physics, UG

23 March: “Dynamic Control of Presynaptic Function in Health and Disease”, Prof. Dr. Nils Brose, Department of Molecular Neurobiology, MPI-EM

20 April: “Non-caveolar caveolins – electrophysiological and metabolic duties outside the caves”, Prof. Dr. Stephan Lehnart, Research Unit for Cellular Biophysics and Translational Cardiology, UMG, cancelled

04 May: “tba”, Prof. Dr. Martin Uecker, Institute for Diagnostic and Interventional Radiology, UMG

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Chair: Stephan E. Lehnart

Steven Marx, M.D., Professor of Medicine from the Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, NY, USA will talk about “Unraveling the mechanisms of fight or flight: it’s all about the neighborhood”.

Abstract: Increased heart rate and contractility of the cardiac ‘fight-or-flight’ response is dependent upon increased entry of calcium into cardiomyocytes. How activation of the sympathetic nervous system modulates calcium influx has been debated since the 1970s. In a series of papers published in Circulation Research, PNAS, JCI and Nature, Steven Marx’s laboratory has solved this mystery. Using innovative approaches, they demonstrated that adrenergic regulation of calcium influx in heart persisted in transgenic mice expressing channels with alanine-substitutions of all of nearly 90 potential PKA phosphorylation sites, overturning long-accepted dogma. Utilizing state-of-the art proximity proteomics and comparing neighboring proteins under stimulating and resting states, Steven Marx identified a small G-protein, Rad, as the long sought-after link to PKA-mediated activation of calcium channels. In the end, the underlying mechanism turns out to be simple and elegant – at baseline, Rad inhibits cardiac calcium channel activity, while PKA phosphorylation of Rad causes it to leave the vicinity of the calcium channel, thereby preventing it from inhibiting the channel. Furthermore, expression of Rad or its homologue Rem imparts stimulation of CaV1.3 and CaV2.2 by PKA, revealing an evolutionarily conserved mechanism that confers adrenergic modulation upon voltage-gated calcium channels expressed in heart, neuroendocrine cells and neurons.

Subsequent to the lecture a “Meet-the-speaker” will be arranged for the members of the MBExC and Hertha Sponer College.

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Wednesday, April 28, 2021

4:00 PM Musical prelude by Kingston Hythe, Q&A session with the musician

5:00 PM Elisabeth Glowatzki (Johns Hopkins University School of Medicine, Baltimore, USA)
“Resolution of subcomponents of synaptic release from postsynaptic currents at inner hair cell ribbon synapses”

6:00 PM Brikha R. Shrestha (Harvard Medical School, Boston, USA)
“Molecular basis of spiral ganglion neuron diversity: a developing story”

5:20 PM Daniel Kerschensteiner (Washington University, St. Louis, USA)
“Local input processing and dual transmitter release of retinal interneuron dendrites”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 2:  “Membrane Protein Targeting”

09 February: “Investigating the molecular architecture of cells with cryo-electron tomography”, Prof. Dr. Rubén Fernández-Busnadiego, Institute of Neuropathology, UMG

23. February: “Recent advances in super-resolutions single-molecule localization microscopy”, Prof. Dr. Jörg Enderlein, Biophysics, Third Institute of Physics, UG

23 March: “Dynamic Control of Presynaptic Function in Health and Disease”, Prof. Dr. Nils Brose, Department of Molecular Neurobiology, MPI-EM

20 April: “Non-caveolar caveolins – electrophysiological and metabolic duties outside the caves”, Prof. Dr. Stephan Lehnart, Research Unit for Cellular Biophysics and Translational Cardiology, UMG, cancelled

04 May: “Computational Magnetic Resonance Imaging”, Prof. Dr. Martin Uecker, Institute for Diagnostic and Interventional Radiology, UMG

For log-in information please contact: heike.conrad@med.uni-goettingen.de

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Wednesday, May 12, 2021

5:00 PM Thomas Coate (Georgetown University, Washington, USA)
“Mechanisms of SGN wiring and firing during ribbon synapse development”

6:00 PM Angela Ballesteros (National Institutes of Health, Bethesda, USA)
“Structural Relationship Between TMC1 and TMEM16 proteins”

5:20 PM Maria (Lania) E. Rubio (University of Pittsburgh, USA)
“Molecular Structure of Auditory Nerve Synapses in the Normal Hearing and in the Hearing Impaired”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “tba”, Prof. Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

The next Women’s Careers and Networking symposium (WoCaNet 2021) taking place from the 27th to the 28th of the coming May.
The aim of WoCaNet is to provide an interactive environment for young female scientiststo find new possibilities and networking opportunities, while learning from the valuable experiences of renowned women & men of diverse professional backgrounds. Register early to secure a spot in one of our workshops to polish those skills that you want to develop further, and career fair to explore various career paths.
Even though this 7th edition of WoCaNet in 2021 will be online due to the pandemic, this grants us an exceptional opportunity to expand our contacts beyond frontiers, as unlike in the previous six years, participants will not be physically limited to the Göttingen area, where the last WoCaNets have taken place.
To the men and everyone reading this who doesn’t identify as female: WoCaNet is also for you! This symposium aims to foster networking opportunities for women to reduce gender gaps in science, and that automatically makes you part of the story too! Give us a vote of trust and follow up on WoCaNet 2021, it could be a great opportunity for your career as well! All genders welcome.

Further information on the website: www.wocanet.uni-goettingen.de

Registration fees:

• Attending the symposium is FREE, but registration is mandatory.
• 10-15 Euro for participation in a workshop

Registration deadline: 30.04.2021

Click here for the poster of the WoCaNet 2021

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Wednesday, May 27, 2021

4:00 PM Musical prelude by Trio Gaia, Q&A session with the musicians

5:00 PM Henrique von Gersdorff (Vollum Institute, Portland, USA)
“Quantal size and quantal content at a ribbon synapse”

6:00 PM Qiuxiang Zhang
“Visualizing hair cell spontaneous activity in zebrafish during ribbon synapse formation”

5:20 PM Anna Lysakowski (University of Illinois, Chicago, USA)
“Mitochondria in the service of hair cells”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “tba”, Prof. Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Wednesday, June 9, 2021

5:00 PM Maria Eugenia Gomez-Casati (Universidad de Buenos Aires, Argentina)
“The Role of the Medial Olivocochlear System in Noise-induced and Age-related Cochlear Synaptopathy”

6:00 PM Lingchao Ji
“Inner hair cell synapse number influences auditory processing”

5:20 PM Shigeki Watanabe (Department of Cell Biology, Johns Hopkins University)
“Spatial and temporal control of synaptic transmission”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “tba”, Prof. Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Chairs: Tobias Moser and Thomas Mager

Professor Adam E. Cohen from the Departments of Chemistry and Chemical Biology, and Physics, Harvard University and Howard Hughes Medical Institute in Cambridge will talk about “All-optical electrophysiology for probing neural circuit dynamics”. 

Abstract

Combined optogenetic perturbation and voltage imaging enables high-resolution mapping of bioelectrical dynamics in intact tissues. I will describe application of these tools to Layer 1 of the mouse barrel cortex. We developed techniques to distinguish the separate contributions of excitatory and inhibitory synaptic inputs to membrane potential. By combining patterned optogenetic stimulation, voltage imaging, and numerical simulations of neural dynamics we discovered surprising phase transitions in the dynamics of L1 interneurons which may affect how the brain regulates attention.

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “Smart solutions for fluorescence nanoscopy”, Prof. Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Wednesday, July 7, 2021

5:00 PM Régis Nouvian (INM, Montpellier, France)
“Mouse model of the human progressive hearing loss DFNA25”

6:00 PM Norbert Babai (University of Erlangen-Nürnberg)
“Cav3.2 T-type calcium channels modulate function in mammalian cone photoreceptors”

5:25 PM Katie Kindt (National Institutes of Health, Bethesda, USA)
“Lighting up ribbon synapse function in zebrafish”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Block 3:  “Nanodomains for Excitability”

18 May: “Formation, maintenance and function of ion channel clusters: How to access Cav1.3 channels in in vitro systems””, Prof. Dr. Claudia Steinem, Institute of Organic and Biomolecular Chemistry, UG

01 June: “MINFLUX and MINSTED”, Prof. Dr. Stefan W. Hell, Department of NanoBiophotonics, MPI-BPC

15 June: “How hearing happens”, Prof. Dr. Tobias Moser, Institute for Auditory Neuroscience, UMG

29 June: “Studying VGCs with combined strategies for molecular fluorescent labeling and high-resolution microscopy/nanocscopy”, Dr. Tobias Kohl / Niko Schwenzer, Research Unit for Cellular Biophysics and Translational Cardiology, UMG

13 July: “Smart solutions for fluorescence nanoscopy”, Dr. Alexander Egner, Department of Optical Nanoscopy, IFNANO Institute for Nanophotonics Goettingen e.V.

For log-in information please contact: heike.conrad@med.uni-goettingen.de

Chair: Prof. Dr. Tobias Moser

Hinrich Staecker, MD, PhD, from the Departments of Otolaryngology, Head and Neck Surgery, University of Kansas Medical Center, Kansas City will talk about “Challenges in translating gene therapy for inner ear disorders” during the upcoming CRC889 Sensory Lecture. 

Abstract:

Our increased understanding of the underlying causes of many hearing disorders has led to the development of molecular therapeutics to address a variety of disorders. The CGF166 (atoh1) human clinical trial has enhanced our ability to model and understand the delivery of viral vectors to the human inner ear and serves as a model for understanding the translation of a range of molecular therapeutics into clinical trials. Key issues emerging from this study are identification of appropriate models for preclinical testing development of improved testing to aid in patient selection and optimization of delivery approaches. There has also been a leap forward in the development of synthetic vectors that can target the inner ear. The next generation of translational studies will address a broader range of inner ear applications including genetic hearing loss, protection of the inner ear and modification of cellular phenotype.

Further information on the CRC 889 website: www.sfb889.uni-goettingen.de

Click here for the poster of the talk.

We would like to announce the upcoming Ribbon Synapses Seminar Series (RSSS) 2021, an online alternative to the long-running series of Ribbon Synapses Symposia (RSS). The RSS are specialized international conferences that have in the past been held in Göttingen, Germany.

This year’s RSSS is jointly organized by the Washington University School of Medicine in St. Louis and the Collaborative Research Center 889 “Cellular Mechanisms of Sensory Processing”. Owing to the pandemic-related travel difficulties it will be held online, aiming for a schedule of ~2-3 talks presented every ~2 weeks.

This seminar series aims to provide an online platform to not only bring together experts in the field, who will present and discuss novel data and provide a detailed overview of the current state of the art of ribbon synapse research, but additionally allow young scientists to present their work in form of a short talk.
Short talks are invited, please mail sfb889@med.uni-goettingen.de to apply.

Thursday, July 22, 2021

5:00 PM Peter Lukasiewicz (Washington University School of Medicine, St. Louis, USA)
“EAAT5 glutamate transporter function in the vertebrate retina”

6:00 PM tba
“tbd”

5:25 PM Richard H. Kramer (Berkeley, University of California, USA)
“Reversing physiological remodeling of the retina to rescue vision in degenerative blindness”

Please visit www.rsss2021.uni-goettingen.de for registration and the latest version of the program (still developing).

For further information, please contact sfb889@med.uni-goettingen.de

Click here for the poster of the RSSS 2021

DATE: 23 August 2021
VENUE: Paulinerkirche Göttingen

This symposium focuses on multiscale X-ray phase-contrast tomography performed at different european synchrotrons. Different organs are visualized in high resolution by X-ray based imaging, ranging from virtual histology of tissues, intraoperative histology, functional imaging in vivo, towards applications in humans. Furthermore, future directions of X-ray based imaging strategies will be discussed by the experts.

We are exited and hopeful that this symposium can take place in-person as planned. However, due to the current COVID-19 restrictions, only a limited number of participants are allowed at the lecture hall in the Paulinerkirche.

Monday, August 23, 2021

10:00 AM Welcome by Frauke Alves, Tim Salditt and Christian Dullin

10:10 AM – 11:40 AM Session 1: Novel technological developments in X-ray based imaging
with talks by Tim Salditt, Hans Hertz and Julia Herzen

11:40 PM Coffee break

12:00 PM – 12:50 PM Session 2: Short selected talks of students
with talks by Jakob Reichmann, Jannis Schaeper, Jonas Albers, Amara Khan and Kian Shaker

12:50 PM Lunch break

1:50 PM – 3:20 PM Session 3: Nano/ small scale imaging and biomedical application
with talks by Alexandra Pacureanu, Liz Duke and Sam Bayat

3:20 PM Coffee break

3:50 PM – 4:50 PM Discussion and presentation

4:50 PM – 6:00 PM Session 4: Towards clinical application
with talks by Alessandro Olivo and Christian Dullin

For registration and further information, please contact fritz.kobe[at]med.uni-goettingen.de

Click here for the poster of the MBExC Symposium 2021 and the programme

DATE: 24-27 August 2021
VENUE: Lokhalle Göttingen

The European Society for Molecular Imaging (ESMI) represents the scientific community involved in multidisciplinary molecular imaging science. This includes basic, preclinical, translational, and clinical research on imaging technologies, methodologies, biomarkers and probes, modeling, and data analysis. Central to its mission is the creation of a collaborative community to pursue new ideas to image biological processes. ESMI strives to transfer this knowledge from experimental imaging studies to the implementation of diagnostic and therapeutic strategies.

The ESMI Board has acknowledged the clear demand by the community to enhance the chance for a f2f EMIM in 2021 rather than to go for another virtual meeting. For that reason the EMIM 2021 was postponed to the last week of August. The subsequent EMIM 2022 is again scheduled for March 2022 in Thessaloniki.

It is with honour and delight that the Opening Lecture will be delivered by Stefan W. Hell.

Further information on the website: www.emim.eu

Click here for the poster of the EMIM 2021

DATE: 31 August  – 02 September 2021

Internal Meeting of the SPP 1926 Next Generation Optogenetics Tools and Application & the Cluster of Excellence Multiscale Bioimaging (MBExC)

organized by Tobias Brügmann, Alexander Gottschalk, Stephan Lehnart, Tobias Moser

DATE: 31 August  – 02 September 2021

Internal Meeting of the SPP 1926 Next Generation Optogenetics Tools and Application & the Cluster of Excellence Multiscale Bioimaging (MBExC)

organized by Tobias Brügmann, Alexander Gottschalk, Stephan Lehnart, Tobias Moser

The Harvard European Alumni Training Network (HEAT-Net) will hold the 3rd Meeting on Frontiers in Neurodegeneration from September 6th until 8th, 2021 at the Max Planck Institute of Experimental Medicine, Göttingen.

Keynote lectures by Brian Bacskai, Bradley T. Hyman, Rudy Tanzi, Xandra Breakefield (Massachusetts General Hospital, Boston) and Lars Lannfelt (University of Uppsala)

Speakers: Tiago Outeiro, Tara Spires, Christine Stadelmann-Nessler, Annakaisa Haapasalo, Monica Garcia-Alloza, Melanie Meyer-Luehmann, Christina Lill, Lars Bertram, Brit Mollenhauer, Christine von Arnim, Karin Danzer, Mikko Hiltunen, Alberto Lleó, Jens Wiltfang, Inga Zerr, Markus Otto, Andre Fischer, Martin Ingelsson

Click here for the preliminary program
Further information about the registration and abstract submission: www.heat-net.uni-goettingen.de/registration/

The Hertha Sponer College Lecture Series is addressed to interested students, PhD candidates, postdocs, and PIs. The overall idea is to fundamentally explain research by providing an overview about the general aims of the six MBExC Research Alliances with special focus on the specific techniques that are developed and applied. The lectures take place on Tuesdays at 5 pm within the semester term, and are offered by MBExC PIs. Subsequent to lecture and discussion, Hertha Sponer College members have the opportunity to “Meet-the-PI” and each other for asking more specific or general questions, networking and socializing.

Session:  “Epigenetic Regulation of Gene Transcritpion”

07 Sept: “Epigenetic processes in heart & brain diseases”, Prof. Dr. André Fischer, Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE)

21 Sept: “Towards therapies against SARS-CoV2 infections”, Prof. Dr. Matthias Dobbelstein, Institute of Molecular Oncology, UMG

05 Oct: “tba”, Prof. Dr. Elisabeth Zeisberg, Department of Cardioloy and Pneumology, UMG

02 Nov: “tba”, Prof. Dr. Silvio Rizzoli, Institute of Neuro- and Sensory Physiology, UMG

16 Nov: “tba”, Prof. Dr. Ralf Ficner, Department of Molecular Structural Biology, Institute for Microbiology & Genetics, UG

For log-in information please contact: heike.conrad@med.uni-goettingen.de