Hertha Sponer College Advanced Methods Course

Hertha Sponer College Advanced Methods Course (Internal Event)

HSC Advanced Methods Workshop in Optogenetics

Optogenetics enables the spatiotemporal control of cellular activity in a reversible manner. Therefore, optogenetic approaches revolutionize research in basic neurosciences and promise future medical treatments, e.g. for sensory restoration. The accurate application of optogenetics strongly depends on the knowledge of the biophysical properties of the optogenetic tool of choice. Participants of the HSC Advanced Methods Workshop will perform patch-clamp experiments in conjunction with laser stimulation in order to learn more about the biophysical properties of
Channelrhodopsins, light-gated ion channels, which are commonly used for light activation of excitable cells. Moreover, they will get insights into adeno-associated virus mediated transduction and hands-on experience in the neuronal photostimulation of primary cultures of rat hippocampal
neurons.

01 – 02 July 2021, 9 – 5 p.m., Institute for Auditory Neuroscience / InnerEarLab, University Medical Center Göttingen, Robert-Koch
Str. 40, 37075 Göttingen

Supervisor: Thomas Mager, MBExC Application Specialist; Institute for Auditory Neuroscience, UMG