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28. August 2020Like

Generation of human brain organoids with the ability to learn

Stem cell technologies are revolutionizing the biomedical field. Scientists at the University Medical Center Göttingen (UMG) in collaboration with research partners of the Cluster of Excellence “Multiscale Bioimaging” (MBExC) and the German Center for Neurodegenerative Disease (DZNE) combined induced pluripotent stem cells (iPSC) and their deep knowledge in the bioengineering
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11. August 2020Like

Dissecting protein assemblies

In an initial application of the powerful MINFLUX nanoscopy technique to cell biology, researchers led by Stefan Hell and Stefan Jakobs have now optically dissected the distribution of individual proteins in a ~ 20-nanometer-sized protein cluster within a cellular organelle in 3D using multiple colors. MINFLUX nanoscopy thus proves to
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5. August 2020Like

CRISPR/Cas9 – GENE EDITING: New therapeutic approach for congenital heart defects

Scientists at the Heart Center of the University Medical Center Göttingen have for the first time found an approach for a personalised therapy option with “gene editing” for the Noonan Syndrome. Publication in the renowned journal “Circulation“. Link to the press release
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30. Juli 2020Like

In one sweep: Visualization of protein mobility in the synapse

A team of scientists around Prof. Dr. Silvio O. Rizzoli and Prof. Dr. Sarah Köster was able to generate the first visualizations of movement of 45 proteins in a cell simultaneously, thus demonstrating the realistic mobility of thousands of protein molecules represented in their realistic shapes and sizes within a
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22. Juli 2020Like

On the way to the optical cochlear implant

Interdisciplinary team of scientists from the University Medical Center Göttingen and the University of Freiburg generate for the first time light-controlled behaviour in deaf rodents using optical cochlear implants based on light-emitting diodes. Published in Science Translational Medicine. Link to the press release
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17. Juli 2020Like

New biosensor detects cell-to-cell transmission of the Parkinson-associated protein α-Synuclein

Scientists of the Cluster of Excellence Multiscale Bioimaging develop a new biosensor capable of detecting the transmission of human α-synuclein, a key protein associated to Parkinson’s disease. Published in Nature Communications. Link to the press release
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Optical cochlear implant in the cochlea of a gerbil
3. Juli 2020Like

Lighting array in the ear: First use of multi-channel cochlear implants with microscale light-emitting diodes

A milestone in hearing research: Researchers at the University Medical Center Göttingen and the University of Freiburg combine for the first time gene therapy in the cochlea with optical cochlear implants to optogenetically activate the auditory pathway in gerbils. Published in EMBO Molecular Medicine. Link to the press release
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26. Juni 2020Like

Coupled hair cells in the inner ear –
„Together we are strong!“

When we hear, the sensory hair cells in the cochlea of the inner ear transduce sound signals of a certain pitch and convert them for transmission to the brain. For the first time, scientists of the Göttingen Campus, the Cluster of Excellence “Multiscale Bioimaging” and the University College London have
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13. Mai 2020Like

Patrick Cramer elected to the National Academy of Sciences

The US-American National Academy of Sciences has elected Patrick Cramer as Foreign Associate. The prestigious academy thus honors the biochemist for his outstanding research on a fundamental process of life – how cells read the information encoded in the genes and how this is regulated. “To have been elected into
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15. April 2020Like

One of the ERC Advanced Grants for Patrick Cramer

Every year, top researchers apply to the European Research Council (ERC) for funding. The highly remunerated ERC Advanced Grants are particularly sought after. Patrick Cramer, Max Planck Director and vice speaker of the MBExC in Göttingen, was successful for the third time – an exceptional achievement. The biochemist investigates how
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