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27. April 20212

Better hearing with optical cochlear implants

Imaging techniques enable decisive step toward development of novel hearing prostheses In cochlear implants background noises compromise the comprehension of speech. The teams of Tobias Moser and Tim Salditt (both MBExC) were now able to use combined imaging techniques of X-ray tomography and fluorescence microscopy to create detailed images of
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26. März 20213

Otto Warburg Medal for Patrick Cramer

The German Society for Biochemistry and Molecular Biology honors the Göttingen Max Planck Director and MBExC member Patrick Cramer with the Otto Warburg Medal. At the virtual event, he will present his latest results from corona research.
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18. März 20213

How synapses maintain their activity despite ageing

Scientists of the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) and the Collaborative Research Center 1286, University Medical Center Göttingen and Max Planck Institute for Dynamics and Self-Organization uncover a link between protein turnover and synaptic activity. Published in Cell Reports. Link to the press release
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17. März 20212

MINSTED resolves fluorescent molecules with resolution at the nanometer scale

Scientists working with MBExC member Stefan Hell at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen and the Heidelberg-based MPI for Medical Research have developed another light microscopy method, called MINSTED, which resolves fluorescently labeled details with molecular sharpness. With MINSTED, Nobel laureate Hell has come full circle.
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15. März 20212

Two Max Planck Institutes in Göttingen become one

The Max Planck Institutes (MPI) for Biophysical Chemistry and for Experimental Medicine will merge. The decision-making bodies of the Max Planck Society (MPS) approved the plan submitted by the two institutes on March 12. Formally, both institutions will be closed and a new MPI will be founded, keeping the existing
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15. März 20211

Register now for the Women’s Carrers and Networks 2021

Until April 30th, 2021 you can register for the next virtual Women’s Careers and Networking symposium (WoCaNet 2021) taking place from the 27th to the 28th of the coming May. The aim of WoCaNet is to provide an interactive environment for young female scientists to find new possibilities and networking
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12. März 20212

Jutta Gärtner successful with DZKJ satellite Göttingen

The Federal Ministry of Education and Research (BMBF) has selected the University Medical Center Göttingen and other scientific partner institutions from Göttingen as new satellite location for the German Centre for Child and Adolescent Health (DZKJ). Prof. Dr. Jutta Gärtner, Director of the Department of Paediatrics and Adolescent Medicine, UMG
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3. März 20211

Radio broadcast on the World Hearing Day

On the World Hearing Day, Prof. Dr. Dirk Beutner from the Department of Otorhinolaryngology, UMG Göttingen and Dr. Marcus Jeschke from the Cognitive Hearing in Primates group at the German Primate Center and UMG are talking about hearing at the Stadtradio Göttingen broadcast “Mittendrin”, organized by the MBExC in collaboration
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26. Februar 20212

A weak heart links to memory impairment

Heart problems cause disturbed gene activity in the brain’s memory center, from which cognitive deficits arise. A team led by Prof. Dr. André Fischer (reserach group leader at the DZNE Göttingen site, Professor at the Department of Psychiatry and Psychotherapy at the UMG and MBExC member) and Prof. Dr. Karl
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18. Februar 20213

Communitas Prize for Viola Priesemann

The Max Planck Society honors the physicist and MBExC member Dr. Viola Priesemann for her science communication during the Corona pandemic, where she advises politicians, gives interviews, writes statements and publishes her scientific work in prestigious journals. Since the beginning of the pandemic, Viola Priesemann has been calculating scenarios of
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9. Februar 20212

“Heart patch” made from stem cells enters world’s first clinical trial

First application in humans: The BioVAT-HF-DZHK20 study intends to investigate the use of heart muscle tissue derived from stem cells for treatment of patients with severe heart failure. The incorporation of heart muscle tissue cultivated in the laboratory is intended to sustainably improve the pumping function of diseased hearts. The
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5. Februar 20212

Synaptic diversity broadens the range of sound we can hear

Hearing occurs when sensory hair cells in the inner ear convert sound into neural signals transmitted to the brain. The sensory hair cells have about a dozen communication points with the auditory nerve fibers, called synapses. Scientists from the Institute for Auditory Neuroscience at the University Medical Center Göttingen discovered
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5. Februar 20212

Awarded doctorate in neuroscientific hearing research

Dr. Alexander Dieter, a young neuroscientist and first author of the MBExC publication “μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve” (published in summer 2020 in the EMBO Molecular Medicine Journal), has been awarded with the doctoral thesis award 2021 of the Studienstiftung des Deutschen Volkes.
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2. Februar 20213

The Hector Science Award goes to Patrick Cramer

The Hector Foundation honors the director of the Max Planck Institute (MPI) for Biophysical Chemistry and member of the MBExC, Patrick Cramer, for his outstanding research in the field of gene transcription. The prize is endowed with 150,000 euros and was awarded at a virtual event on January 29.
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29. Januar 20212

Alternative to cardiac catheter examination

Diastolic heart failure can be reliably detected with the help of a newly developed magnetic resonance imaging (MRI) technology, shows a study by the Göttingen partner site of the German Centre for Cardiovascular Research (DZHK). Until now, this was only possible with an invasive cardiac catheter examination, which is very
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26. Januar 20213

Patrick Cramer receives the 2021 Louis-Jeantet Prize for Medicine

The research award is one of the most prestigious in Europe and endowed with 500,000 Swiss francs. With this prize the Louis-Jeantet Foundation honors the director at the Max Planck Institute (MPI) for Biophysical Chemistry and member of the MBExC for his pioneering work in the field of gene transcription.
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25. Januar 20215

Carola Gregor and Antoine Huet are new MBExC Junior Fellows

The Cluster of Excellence “Multiscale Bioimaging” (MBExC) welcomes Dr. Carola Gregor and Dr. Antoine Huet as new Junior Fellows starting in January 2021 for 3 years. Dr. Carola Gregor will focus with her project Bioluminescence imaging of neurons and cardiomyocytes  on the bioluminescence system from bacteria to develop new tools
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18. Januar 20213

Why remdesivir does not fully stop the coronavirus

Remdesivir is the first drug against Covid-19 to be conditionally approved in Europe and the United States. The drug is designed to suppress the rapid replication of the SARS-CoV-2 virus in human cells by blocking the viral copying machine, called RNA polymerase. Researchers at the Max Planck Institute (MPI) for
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12. Januar 20213

Jörg Enderlein receives ERC Advanced Grant

Physicist Professor and member of the Excellence Cluster “Multiscale Bioimaging” (MBExC) Jörg Enderlein from the University of Göttingen has been awarded an Advanced Grant by the European Research Council (ERC). The ERC has supported Enderlein’s project – “Single-molecule, metal-induced energy transfer” – since the beginning of January 2021. The grant
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18. November 20202

“Scientific Grand prize” of the Fondation Pour l’Audition for Prof. Dr. Tobias Moser

Prof. Dr. Tobias Moser receives high distinction from French Fondation Pour l’Audition: “Scientific Grand Prize” 2020 honours his pioneering work on the optical cochlear implant for the treatment of hearing loss. The prize is endowed with 100,000 euros. Link to the press release
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17. November 20202

Physicist Dr. Jan Huisken nominated for top level research at the MBExC

Göttingen University receives another Alexander von Humboldt Professorship (mbexc/umg) The University of Göttingen was once again successful in the competition for the most highly endowed German research award: Physicist Dr. Jan Huisken, nominated by the University of Göttingen, has been awarded an Alexander von Humboldt Professorship. The professorship, financed by
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12. November 20202

Mini-Symposium “Excitable cell networks in heart and brain”

on November 23rd and 30th, 2020, from 1 pm until 5 pm via ZOOM This mini symposium focuses on cross-scale analysis of information processing in cardiac and/or neural networks by means of imaging, optogenetics and/or electrophysiology as well as computational modelling. Such cross-scale analysis propagates insights from the structural and
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9. November 20201

Exhibition „Sinneswelten“ (World of Senses)

The exhibition “Sinneswelten” provides special insights into the wonderful world of senses at the cellular level of sensory cells and neurons from an artistic perspective. The displayed images are results of the daily work of the scientists at the Collaborative Research Center 889 (CRC889). They have been acquired with different
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6. November 20203

ERC Synergy Grants for Göttingen neuroscientists

Professors Silvio Rizzoli from Göttingen, Director of the Institute of Neuro- and Sensory Physiology at the University Medical Center Göttingen (UMG), and Nils Brose, Director of the Department of Molecular Neurobiology at the Max Planck Institute of Experimental Medicine (MPI-EM), both members of the MBExC, are among the recipients of
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21. Oktober 20203

World record resolution in cryo electron microscopy

Holger Stark and his team at the Max Planck Institute (MPI) for Biophysical Chemistry have broken a crucial resolution barrier in cryo electron microscopy. The scientists succeeded in observing single atoms in a protein structure and taking the sharpest images ever with this method. Such unprecedented details are essential to
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20. Oktober 20201

Coronavirus: Study finds further door opener into the cell

The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior. Neuropilin-1 is localized in the respiratory and olfactory epithelia, which could be a strategically important
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28. August 20201

Generation of human brain organoids with the ability to learn

Stem cell technologies are revolutionizing the biomedical field. Scientists at the University Medical Center Göttingen (UMG) in collaboration with research partners of the Cluster of Excellence “Multiscale Bioimaging” (MBExC) and the German Center for Neurodegenerative Disease (DZNE) combined induced pluripotent stem cells (iPSC) and their deep knowledge in the bioengineering
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21. August 20201

New insights into lung tissue in Covid-19 disease

Physicists at the University of Göttingen and the Cluster of Excellence “Multiscale Bioimaging” (MBExC), together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique that enables high resolution and three-dimensional representation of damaged lung tissue following severe Covid-19. Using a special X-ray
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11. August 20201

Dissecting protein assemblies

In an initial application of the powerful MINFLUX nanoscopy technique to cell biology, researchers led by Stefan Hell and Stefan Jakobs have now optically dissected the distribution of individual proteins in a ~ 20-nanometer-sized protein cluster within a cellular organelle in 3D using multiple colors. MINFLUX nanoscopy thus proves to
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5. August 20201

CRISPR/Cas9 – GENE EDITING: New therapeutic approach for congenital heart defects

Scientists at the Heart Center of the University Medical Center Göttingen have for the first time found an approach for a personalised therapy option with “gene editing” for the Noonan Syndrome. Publication in the renowned journal “Circulation“. Link to the press release
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30. Juli 20201

In one sweep: Visualization of protein mobility in the synapse

A team of scientists around Prof. Dr. Silvio O. Rizzoli and Prof. Dr. Sarah Köster was able to generate the first visualizations of movement of 45 proteins in a cell simultaneously, thus demonstrating the realistic mobility of thousands of protein molecules represented in their realistic shapes and sizes within a
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22. Juli 20201

On the way to the optical cochlear implant

Interdisciplinary team of scientists from the University Medical Center Göttingen and the University of Freiburg generate for the first time light-controlled behaviour in deaf rodents using optical cochlear implants based on light-emitting diodes. Published in Science Translational Medicine. Link to the press release
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17. Juli 20201

New biosensor detects cell-to-cell transmission of the Parkinson-associated protein α-Synuclein

Scientists of the Cluster of Excellence Multiscale Bioimaging develop a new biosensor capable of detecting the transmission of human α-synuclein, a key protein associated to Parkinson’s disease. Published in Nature Communications. Link to the press release
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Optical cochlear implant in the cochlea of a gerbil
3. Juli 2020Like

Lighting array in the ear: First use of multi-channel cochlear implants with microscale light-emitting diodes

A milestone in hearing research: Researchers at the University Medical Center Göttingen and the University of Freiburg combine for the first time gene therapy in the cochlea with optical cochlear implants to optogenetically activate the auditory pathway in gerbils. Published in EMBO Molecular Medicine. Link to the press release
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26. Juni 2020Like

Coupled hair cells in the inner ear –
„Together we are strong!“

When we hear, the sensory hair cells in the cochlea of the inner ear transduce sound signals of a certain pitch and convert them for transmission to the brain. For the first time, scientists of the Göttingen Campus, the Cluster of Excellence “Multiscale Bioimaging” and the University College London have
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13. Mai 20201

Patrick Cramer elected to the National Academy of Sciences

The US-American National Academy of Sciences has elected Patrick Cramer as Foreign Associate. The prestigious academy thus honors the biochemist for his outstanding research on a fundamental process of life – how cells read the information encoded in the genes and how this is regulated. “To have been elected into
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15. April 20201

One of the ERC Advanced Grants for Patrick Cramer

Every year, top researchers apply to the European Research Council (ERC) for funding. The highly remunerated ERC Advanced Grants are particularly sought after. Patrick Cramer, Max Planck Director and vice speaker of the MBExC in Göttingen, was successful for the third time – an exceptional achievement. The biochemist investigates how
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8. November 20193

Jutta Gärtner awarded Hamburg Science Prize 2019

Prof. Dr. Jutta Gärtner, Director of the Department of Paediatrics and Adolescent Medicine at the University Medical Center Göttingen and MBExC member, has received the Hamburg Science Prize 2019 “Congenital Rare Diseases” in Hamburg City Hall in front of over 100 invited guests. With this award, the Academy of Sciences
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23. September 20193

Sarah Köster receives EPS Emmy Noether Distinction for Women in Physics 2019

The physicist Prof. Dr. Sarah Köster from the University of Göttingen and member of the MBExC has received the EPS Emmy Noether Distinction for Women in Physics 2019 (summer) of the European Physical Society (EPS). The EPS honours Köster’s groundbreaking contributions to the physics of biological cells and biopolymers, especially
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