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Heart problems cause disturbed gene activity in the brain’s memory center, from which cognitive deficits arise. A team led by Prof. Dr. André Fischer (reserach group leader at the DZNE Göttingen site, Professor at the Department of Psychiatry and Psychotherapy at the UMG and MBExC member) and Prof. Dr. Karl News

The Max Planck Society honors the physicist and MBExC member Dr. Viola Priesemann for her science communication during the Corona pandemic, where she advises politicians, gives interviews, writes statements and publishes her scientific work in prestigious journals. Since the beginning of the pandemic, Viola Priesemann has been calculating scenarios of News

First application in humans: The BioVAT-HF-DZHK20 study intends to investigate the use of heart muscle tissue derived from stem cells for treatment of patients with severe heart failure. The incorporation of heart muscle tissue cultivated in the laboratory is intended to sustainably improve the pumping function of diseased hearts. The News

Hearing occurs when sensory hair cells in the inner ear convert sound into neural signals transmitted to the brain. The sensory hair cells have about a dozen communication points with the auditory nerve fibers, called synapses. Scientists from the Institute for Auditory Neuroscience at the University Medical Center Göttingen discovered News

Dr. Alexander Dieter, a young neuroscientist and first author of the MBExC publication “μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve” (published in summer 2020 in the EMBO Molecular Medicine Journal), has been awarded with the doctoral thesis award 2021 of the Studienstiftung des Deutschen Volkes. News

The Hector Foundation honors the director of the Max Planck Institute (MPI) for Biophysical Chemistry and member of the MBExC, Patrick Cramer, for his outstanding research in the field of gene transcription. The prize is endowed with 150,000 euros and was awarded at a virtual event on January 29. News

Diastolic heart failure can be reliably detected with the help of a newly developed magnetic resonance imaging (MRI) technology, shows a study by the Göttingen partner site of the German Centre for Cardiovascular Research (DZHK). Until now, this was only possible with an invasive cardiac catheter examination, which is very News

The research award is one of the most prestigious in Europe and endowed with 500,000 Swiss francs. With this prize the Louis-Jeantet Foundation honors the director at the Max Planck Institute (MPI) for Biophysical Chemistry and member of the MBExC for his pioneering work in the field of gene transcription. News

The Cluster of Excellence “Multiscale Bioimaging” (MBExC) welcomes Dr. Carola Gregor and Dr. Antoine Huet as new Junior Fellows starting in January 2021 for 3 years. Dr. Carola Gregor will focus with her project Bioluminescence imaging of neurons and cardiomyocytes  on the bioluminescence system from bacteria to develop new tools News

Remdesivir is the first drug against Covid-19 to be conditionally approved in Europe and the United States. The drug is designed to suppress the rapid replication of the SARS-CoV-2 virus in human cells by blocking the viral copying machine, called RNA polymerase. Researchers at the Max Planck Institute (MPI) for News

Physicist Professor and member of the Excellence Cluster “Multiscale Bioimaging” (MBExC) Jörg Enderlein from the University of Göttingen has been awarded an Advanced Grant by the European Research Council (ERC). The ERC has supported Enderlein’s project – “Single-molecule, metal-induced energy transfer” – since the beginning of January 2021. The grant News

Prof. Dr. Tobias Moser receives high distinction from French Fondation Pour l’Audition: “Scientific Grand Prize” 2020 honours his pioneering work on the optical cochlear implant for the treatment of hearing loss. The prize is endowed with 100,000 euros. Link to the press release News

Göttingen University receives another Alexander von Humboldt Professorship (mbexc/umg) The University of Göttingen was once again successful in the competition for the most highly endowed German research award: Physicist Dr. Jan Huisken, nominated by the University of Göttingen, has been awarded an Alexander von Humboldt Professorship. The professorship, financed by News

on November 23rd and 30th, 2020, from 1 pm until 5 pm via ZOOM This mini symposium focuses on cross-scale analysis of information processing in cardiac and/or neural networks by means of imaging, optogenetics and/or electrophysiology as well as computational modelling. Such cross-scale analysis propagates insights from the structural and News

The exhibition “Sinneswelten” provides special insights into the wonderful world of senses at the cellular level of sensory cells and neurons from an artistic perspective. The displayed images are results of the daily work of the scientists at the Collaborative Research Center 889 (CRC889). They have been acquired with different News

Professors Silvio Rizzoli from Göttingen, Director of the Institute of Neuro- and Sensory Physiology at the University Medical Center Göttingen (UMG), and Nils Brose, Director of the Department of Molecular Neurobiology at the Max Planck Institute of Experimental Medicine (MPI-EM), both members of the MBExC, are among the recipients of News

Holger Stark and his team at the Max Planck Institute (MPI) for Biophysical Chemistry have broken a crucial resolution barrier in cryo electron microscopy. The scientists succeeded in observing single atoms in a protein structure and taking the sharpest images ever with this method. Such unprecedented details are essential to News

The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior. Neuropilin-1 is localized in the respiratory and olfactory epithelia, which could be a strategically important News

Stem cell technologies are revolutionizing the biomedical field. Scientists at the University Medical Center Göttingen (UMG) in collaboration with research partners of the Cluster of Excellence “Multiscale Bioimaging” (MBExC) and the German Center for Neurodegenerative Disease (DZNE) combined induced pluripotent stem cells (iPSC) and their deep knowledge in the bioengineering News

Physicists at the University of Göttingen and the Cluster of Excellence “Multiscale Bioimaging” (MBExC), together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique that enables high resolution and three-dimensional representation of damaged lung tissue following severe Covid-19. Using a special X-ray News

In an initial application of the powerful MINFLUX nanoscopy technique to cell biology, researchers led by Stefan Hell and Stefan Jakobs have now optically dissected the distribution of individual proteins in a ~ 20-nanometer-sized protein cluster within a cellular organelle in 3D using multiple colors. MINFLUX nanoscopy thus proves to News

Scientists at the Heart Center of the University Medical Center Göttingen have for the first time found an approach for a personalised therapy option with “gene editing” for the Noonan Syndrome. Publication in the renowned journal “Circulation“. Link to the press release News

A team of scientists around Prof. Dr. Silvio O. Rizzoli and Prof. Dr. Sarah Köster was able to generate the first visualizations of movement of 45 proteins in a cell simultaneously, thus demonstrating the realistic mobility of thousands of protein molecules represented in their realistic shapes and sizes within a News

Interdisciplinary team of scientists from the University Medical Center Göttingen and the University of Freiburg generate for the first time light-controlled behaviour in deaf rodents using optical cochlear implants based on light-emitting diodes. Published in Science Translational Medicine. Link to the press release News

Scientists of the Cluster of Excellence Multiscale Bioimaging develop a new biosensor capable of detecting the transmission of human α-synuclein, a key protein associated to Parkinson’s disease. Published in Nature Communications. Link to the press release News

A milestone in hearing research: Researchers at the University Medical Center Göttingen and the University of Freiburg combine for the first time gene therapy in the cochlea with optical cochlear implants to optogenetically activate the auditory pathway in gerbils. Published in EMBO Molecular Medicine. Link to the press release News

When we hear, the sensory hair cells in the cochlea of the inner ear transduce sound signals of a certain pitch and convert them for transmission to the brain. For the first time, scientists of the Göttingen Campus, the Cluster of Excellence “Multiscale Bioimaging” and the University College London have News

The US-American National Academy of Sciences has elected Patrick Cramer as Foreign Associate. The prestigious academy thus honors the biochemist for his outstanding research on a fundamental process of life – how cells read the information encoded in the genes and how this is regulated. “To have been elected into News

Every year, top researchers apply to the European Research Council (ERC) for funding. The highly remunerated ERC Advanced Grants are particularly sought after. Patrick Cramer, Max Planck Director and vice speaker of the MBExC in Göttingen, was successful for the third time – an exceptional achievement. The biochemist investigates how News

Prof. Dr. Jutta Gärtner, Director of the Department of Paediatrics and Adolescent Medicine at the University Medical Center Göttingen and MBExC member, has received the Hamburg Science Prize 2019 “Congenital Rare Diseases” in Hamburg City Hall in front of over 100 invited guests. With this award, the Academy of Sciences News

The physicist Prof. Dr. Sarah Köster from the University of Göttingen and member of the MBExC has received the EPS Emmy Noether Distinction for Women in Physics 2019 (summer) of the European Physical Society (EPS). The EPS honours Köster’s groundbreaking contributions to the physics of biological cells and biopolymers, especially News