The MBExC
Multiscale Bioimaging (MBExC) -2067- is a Cluster of Excellence of the University of Göttingen, Germany and is funded by the German Federal Government and the Länder (federal states) since 2019.
Research at the MBExC is aimed at the heart and the brain as disorders of these organs are major causes of disability and death. The electrically excitable cells of these widely distinct organs, cardiomyocytes and neurons, have surprisingly many physiological properties in common. The goal of the MBExC is to decipher disease relevant nanoscale functional units in the heart and the brain by using a multiscale approach that integrates research on nanoscale units with analyses of excitable cell networks by using state-of-the-art bioimaging techniques. Together with an interdisciplinary research network across the Göttingen Campus, we provide unique insights into both cardiac and neural networks and develop innovative therapeutic strategies for disorders affecting the heart, the brain, or both.
Hertha Sponer College
Multiscale integrative research performed by MBExC scientists offers unique opportunities for the interdisciplinary training of early career researchers coming from a basic science or medical background. The Hertha Sponer College targets particularly talented students and early career researchers interested in further personalized research training and career advice to spark and foster enthusiasm for research at the boundary of the natural sciences and biomedicine. The overall aim is to promote cutting-edge, interdisciplinary early career researchers on their way to independence, to thus educate a new generation of future research leaders.
Every year, top researchers apply to the European Research Council (ERC) for funding. The highly remunerated ERC Advanced Grants are particularly sought after. Patrick Cramer, Max Planck Director
The US-American National Academy of Sciences has elected Patrick Cramer as Foreign Associate. The prestigious academy thus honors the biochemist for his outstanding research on a fundamental process
When we hear, the sensory hair cells in the cochlea of the inner ear transduce sound signals of a certain pitch and convert them for transmission to the
A milestone in hearing research: Researchers at the University Medical Center Göttingen and the University of Freiburg combine for the first time gene therapy in the cochlea with
Scientists of the Cluster of Excellence Multiscale Bioimaging develop a new biosensor capable of detecting the transmission of human α-synuclein, a key protein associated to Parkinson’s disease. Published
Interdisciplinary team of scientists from the University Medical Center Göttingen and the University of Freiburg generate for the first time light-controlled behaviour in deaf rodents using optical cochlear
A team of scientists around Prof. Dr. Silvio O. Rizzoli and Prof. Dr. Sarah Köster was able to generate the first visualizations of movement of 45 proteins in
Scientists at the Heart Center of the University Medical Center Göttingen have for the first time found an approach for a personalised therapy option with “gene editing” for
In an initial application of the powerful MINFLUX nanoscopy technique to cell biology, researchers led by Stefan Hell and Stefan Jakobs have now optically dissected the distribution of
Physicists at the University of Göttingen and the Cluster of Excellence “Multiscale Bioimaging” (MBExC), together with pathologists and lung specialists at the Medical University of Hannover, have developed
Stem cell technologies are revolutionizing the biomedical field. Scientists at the University Medical Center Göttingen (UMG) in collaboration with research partners of the Cluster of Excellence “Multiscale Bioimaging”
Holger Stark and his team at the Max Planck Institute (MPI) for Biophysical Chemistry have broken a crucial resolution barrier in cryo electron microscopy. The scientists succeeded in
Dialogue
Communicating scientific findings to the local, regional, national, and international public, and raising awareness about integrative research and topics of MBExC is of major importance for us and
