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European funding for Rubén Fernández Busnadiego
31.01.2023

European funding for Rubén Fernández Busnadiego

Expert in cryo-electron microscopy at the University Medical Center Göttingen receives Consolidator Grant of the European Research Council to investigate the membrane architecture of nerve cells and its pathological alterations in axonopathies. (mbexc/umg) Prof. Dr. Rubén Fernández Busnadiego from the Institute for Neuropathology at the University Medical Center Göttingen (UMG)
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European top funding for investigating the exciting mechanisms of mitochondrial gene expression
05.10.2022

European top funding for investigating the exciting mechanisms of mitochondrial gene expression

Prof. Dr. Peter Rehling, cell biochemist at the University Medical Center Göttingen recives for the second time an Advanced Grant of the European Research Council (ERC). (umg/mbexc) Prof. Dr. Peter Rehling, Director of the Institute of Cellular Biochemistry at the University Medical Center Göttingen (UMG), spokesperson of the Göttingen Collaborative
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State of Lower Saxony promotes the preclinical development of the optical cochlear implant
12.08.2022

State of Lower Saxony promotes the preclinical development of the optical cochlear implant

The state of Lower Saxony and the Volkswagen Foundation approve funding for scientists of the UMG and the MBExC Cluster of Excellence of about 1 milion euros of the “SPRUNG” (formerly: “Niedersächsisches Vorab”) for the development of the optical cochlear implant for the restoration of hearing in humans. (umg/mbexc) Hearing
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Stefan Hell elected to the Order Pour le mérite
27.07.2022

Stefan Hell elected to the Order Pour le mérite

The association honors the Nobel laureate in chemistry and director of the Max Planck Institute (MPI) for Multidisciplinary Natural Sciences in Göttingen for his special services to science. Admission to the Order is one of the highest honors that can be bestowed on researchers or artists in Germany. In addition
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Unique technology platform at the MBExC Cluster of Excellence combines cellular electrophysiology and optogenetics
22.07.2022

Unique technology platform at the MBExC Cluster of Excellence combines cellular electrophysiology and optogenetics

New technology platform combines high-throughput recordings of cellular electrophysiology of isolated cardiomyocytes and neurons and their optical stimulation with light. Electrical activity is one of the most important common features of the heart and the brain. The goal of the Göttingen Cluster of Excellence “Multiscale Bioimaging: From Molecular Machines to
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Molecular map of the synapse
15.07.2022

Molecular map of the synapse

Scientists at the Institute for Auditory Neuroscience, UMG, the Max Planck Institute for Multidisciplinary Sciences and the abberior Instruments GmbH apply high-resolution 3D-MINFLUX technology for precise 3D representation of the molecular organization in the active zone of rod photoreceptor cells. Published in Science Advances. (umg/mbexc) For the processing of sensory
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The first light-controlled drug that could improve the hearing of people with cochlear implants
20.05.2022

The first light-controlled drug that could improve the hearing of people with cochlear implants

Researchers at the University Medical Center Göttingen and the Institute for Bioengineering of Catalonia (IBEC) in Spain achieve, for the first time, in vivo light-activated auditory stimulation without the need for genetic manipulation. This new light-controlled drug, capable of triggering the neural pathways involved in hearing, can contribute to improving
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How Junctophilins organize electrically excitable cells
11.05.2022

How Junctophilins organize electrically excitable cells

Experts from the University Medical Center Göttingen and the Baylor College of Medicine in Houston, Texas, summarize 20 years of Junctophilin research, new molecular analyses, and the role of Junctophilins in the development of human diseases in a comprehensive in-depth review article. Published with Spotlight Cover in the renowned journal
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European funding for excellent research on hearing
26.04.2022

European funding for excellent research on hearing

Auditory neuroscientist of the University Medical Center Göttingen receives Advanced Grant of the European Research Council for the second time. Tobias Moser, MD, Director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen (UMG) was awarded an Advanced Grant of the European Research Council (ERC). The ERC
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A new tool for optogenetics: human receptor for studying cell function with light
14.04.2022

A new tool for optogenetics: human receptor for studying cell function with light

Scientists of the University Medical Center Göttingen identify the human OPN5 receptor as a new target to activate cells and to study the principles of how cells communicate with each other. Published on 1 April 2022 in the renowned journal Nature Communications. Gq proteins and the signaling cascade they trigger
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How matrix recycling keeps the brain flexible
08.12.2021

How matrix recycling keeps the brain flexible

Scientists of the Cluster of Excellence Multiscale Bioimaging describe a new mechanism that supports synaptic plasticity in the adult brain. Published in Nature Communications. The extracellular matrix (ECM) gives cell assemblies their structure and plays an important role in cell communication and control. In the adult brain, it forms lattices
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Targeting gene expression in mitochondria
23.11.2021

Targeting gene expression in mitochondria

Scientists of the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) and the Collaborative Research Center 1190 develop novel strategy to investigate gene expression in mitochondria. Published in “Cell”. Mitochondria are considered the power plants of cells because they generate energy from our food with the help of oxygen. The machinery
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Jan Huisken takes up Humboldt-Professorship
08.10.2021

Jan Huisken takes up Humboldt-Professorship

Physicist strengthens MBExC research program in the field of multiscale biology. (mbexc/pug/umg) Physicist Prof. Dr. Jan Huisken has taken up his Alexander von Humboldt Professorship at the University of Göttingen. He was awarded the prestigious chair after successful nomination by the University in November last year. As a member of
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The MBExC welcomes Jun.-Prof. Dr. Nadja Simeth
01.10.2021

The MBExC welcomes Jun.-Prof. Dr. Nadja Simeth

Chemist Nadja Simeth just started building-up her own junior research group for Molecular Labeling Chemistry at the University of Göttingen. The expert in the field of organic chemistry and photochemistry supports the research of the MBExC Cluster of Excellence. (mbexc) The chemist Dr. Nadja Simeth has been awarded a junior
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Revolutionary high-performance microscopy for the Göttingen Cluster of Excellence MBExC
20.05.2021

Revolutionary high-performance microscopy for the Göttingen Cluster of Excellence MBExC

The German Research Foundation and the State of Lower Saxony are funding the acquisition of an instrumentation set for cryo-electron microscopy/tomography for UMG professor Rubén Fernández-Busnadiego at the Cluster of Excellence MBExC. The instruments were delivered in April and set up in premises of the Faculty of Physics at the
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Better hearing with optical cochlear implants
27.04.2021

Better hearing with optical cochlear implants

Understanding spoken words, developing normal speech – cochlear implants enable people with profound hearing impairment to gain a great deal in terms of quality of life. However, background noises are problematic, they significantly compromise the comprehension of speech of people with cochlear implants. The team led by Tobias Moser from
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How synapses maintain their activity despite ageing
18.03.2021

How synapses maintain their activity despite ageing

Scientists of the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) and the Collaborative Research Center 1286, University Medical Center Göttingen and Max Planck Institute for Dynamics and Self-Organization uncover a link between protein turnover and synaptic activity. Published in Cell Reports. (mbexc/umg) Synapses, the communication sites between nerve cells, are
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Synaptic diversity broadens the range of sound we can hear
05.02.2021

Synaptic diversity broadens the range of sound we can hear

Hearing occurs when sensory hair cells in the inner ear convert sound into neural signals transmitted to the brain. The sensory hair cells have about a dozen communication points with the auditory nerve fibers, called synapses. Scientists from the Institute for Auditory Neuroscience at the University Medical Center Göttingen discovered
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