may, 2023
Event Details
Dr. Daniel Hillier from the Functional Imaging Unit, German Primate Center (DPZ), Göttingen will talk about “Optogenetics in large-animal models”
Abstract
Structure and function of the visual cortex of humans is markedly different from that of mice, the latter being the most widely adopted mammalian model species. Some of the differences between human and mouse vision are obvious: humans have frontally-looking while mice have laterally-looking eyes; and – most importantly – humans have retinal specialization for high-acuity vision while mice do not. Genetically-targeted modulation of neuronal function by light has become a standard tool in the mouse model. In contrast, using optogenetics to understand circuit function or to restore lost sensory drive in large-animal models remain difficult. In this talk I will provide an overview of the developments we pursue to develop optogenetic stimulation and activity readout techniques applicable to large-animal species.
Chairs: Tobias Moser and Thomas Mager
Poster of the talk: 
