bioRxiv

Authors Aakhte M, Mueller GF, Li J, Weiss KR, Roos L, Diniz AM, Wenzel J, Schwaninger M, Moser T, Huisken J Journal BioRxiv Citation bioRxiv 2025.02.21.639411. Abstract Light sheet microscopy is the ideal technique for multiscale imaging of large and cleared tissues, and it is desirable to achieve the highest

Authors Vos BE, Vadapalli Y, Muenker TM, Jentoft IMA, Todisco E, Eskandari MA, Schuh M, Lenart P, Betz T Journal BioRxiv Citation bioRxiv 2025.02.17.638579. Abstract The mechanical properties of the cytoplasm and nucleoplasm are crucial for the correct and robust functioning of a cell and play a key role in

Authors Mücher B, Garrido-Charles A, Cyganek L, Bruegmann T, Dalkara D, Siveke I, Herlitze S Journal BioRxiv Citation bioRxiv 2025.02.06.636923. Abstract Activation of G protein coupled receptors coupling to the Gi/o pathway leads to the activation of G protein-activated inward rectifier potassium channels (GIRK) in a fast membrane-delimited manner in

Authors Revah O, Wolf F, Gutnick MJ, Neef A Journal Biorxiv Citation bioRxiv 2024.02.15.580451. Abstract Cortical function reflects the activities of populations of neurons. How accurately they can encode information depends on the speed with which each neuron can respond to input, as revealed by dynamic gain analysis. Theory predicts

Authors Stoldt S, Maass F, Weber M, Dennerlein S, Ilgen P, Gaertner J, Canfes A, Schweighofer SV, Jans DC, Rehling P, Jakobs S Journal BioRxiv Citation bioRxiv 2025.01.23.634455. Abstract Mitochondria contain their own DNA (mtDNA) and a dedicated gene expression machinery. As the mitochondrial dimensions are close to the diffraction

Authors Maestro-Lopez M, Cheng TC, Muntaner J, Menendez M, Alonso M, Schweitzer A, Cuellar J, Valpuesta JM, Sakata E Journal BioRxiv Citation bioRxiv 2025.01.22.633148. Abstract The 26S proteasome primarily degrades proteins marked by polyubiquitin chains. Although ubiquitin-independent pathways for proteasomal degradation exist, the mechanisms involved remain poorly understood. Bag1 links

Authors Jimenez AJ, Isensee J, Hofemeier A, Krueger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal BioRxiv Citation bioRxiv 2025.01.22.633835. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological phenomena such as cancer

Authors Feyerabend M, Pommer S, Jimenez-Sosa MS, Rachel J, Sunstrum JK, Preuss F, Mestern S, Hinkel R, Mietsch M, Viyajraghavan S, Everling S, Treue S, Arnsten AFT, Lewis DA, Wolf F, Murray J, Muller L, McCarroll S, Krienen F, Datta D, Jing Wang X, Tripathy S, Gonzalez-Burgos G, Inoue W,

Authors Harland LTG, Lohoff T, Koulena N, Pierson N, Pape C, Ameen F, Griffiths J, Theeuwes B, Wilson NK, Kreshuk A, Reik W, Nichols J, Cai L, Marioni JC, Gottgens B, Ghazanfar S Journal BioRxiv Citation bioRxiv 2024.12.12.628063. Abstract At the onset of murine gastrulation, pluripotent epiblast cells migrate through

Authors Muth S, Moschref F, Freckmann L, Mutschall S, Garcia-Plaza I, Bahr JN, Petrovic A, Do TT, Schwarze V, Archit A, Weyand K, Michanski S, Maus L, Imig C, Brose N, Wichmann C, Fernandez-Busnadiego R, Moser T, Rizzoli SO, Cooper BH, Pape C Journal BioRxiv Citation bioRxiv 2024.12.02.626387. Abstract Electron