bioRxiv

Authors Amin F, Stone JT, König C, Mancini N, Murakami K, Bidaye SS, Heim MM, Owald D, Majumder U, Grunwald Kadow IC, Pierzchlińska A, Litwin-Kumar A, Barnstedt O, Gerber B Journal BioRxiv Citation bioRxiv 2025.07.07.663268. Abstract It was classically suggested that behaviour can cause emotions (Darwin 1872). For example, smiling

Authors Chandran A, Agarwal A, Wang T, Amaral L, Chaves SR, Outeiro TF, Lautenschlager J Journal BioRxiv Citation bioRxiv 2025.06.06.657340. Abstract Alpha-synuclein is a pre-synaptic protein implicated in synucleinopathies like Parkinson’s disease and Dementia with Lewy Bodies, where it accumulates in intracellular aggregates termed Lewy bodies and Lewy neurites. Recent

Authors Haertter D, Hauke L, Driehorst T, Nishi K, Long J, Tiburcy M, Berecic B, Primeßnig A, Bao G, Cyganek L, Schmidt CF, Zimmermann WH Journal BioRxiv Citation bioRxiv 2025.04.29.650605. Abstract Cardiomyocyte function critically depends on sarcomere dynamics and their organization in myofibrils. To uncover how cardiomyocyte function emerges from

Authors Gönenc II, Wolff A, Busley AV, Wieland A, Tijhuis A, Müller C, Wardenaar R, Argyriou L, Kaulfuß S, Räschle M, Spierings DCJ, Foijer F, Bastians H, Yigit G, Zibat A, Cyganek L, Wollnik B Journal BioRxiv Citation bioRxiv 2025.04.17.649287. Abstract Biallelic loss-of-function (LoF) variants in the BTRR complex members

Authors Kim M, Matthes D, Frieg B, Leonov A, Ryazanov S, Bleher D,Grotegerd AK, Dienemann C, Giese A, Schröder GF, Becker S, Herfert K, de Groot BL, Andreas LB, Griesinger C Journal BioRxiv Citation bioRxiv 2025.04.21.649837. Abstract Accumulation of α-synuclein (αSyn) aggregates in the human brain is the major hallmark

Authors Mücher B, Garrido-Charles A, Cyganek L, Bruegmann T, Dalkara D, Siveke I, Herlitze S Journal BioRxiv Citation bioRxiv 2025.02.06.636923. Abstract Activation of G protein coupled receptors coupling to the Gi/o pathway leads to the activation of G protein-activated inward rectifier potassium channels (GIRK) in a fast membrane-delimited manner in

Authors Revah O, Wolf F, Gutnick MJ, Neef A Journal Biorxiv Citation bioRxiv 2024.02.15.580451. Abstract Cortical function reflects the activities of populations of neurons. How accurately they can encode information depends on the speed with which each neuron can respond to input, as revealed by dynamic gain analysis. Theory predicts

Authors Feyerabend M, Pommer S, Jimenez-Sosa MS, Rachel J, Sunstrum JK, Preuss F, Mestern S, Hinkel R, Mietsch M, Viyajraghavan S, Everling S, Treue S, Arnsten AFT, Lewis DA, Wolf F, Murray J, Muller L, McCarroll S, Krienen F, Datta D, Jing Wang X, Tripathy S, Gonzalez-Burgos G, Inoue W,

Authors Albariqi MMA, Baauw SMG, Fens SPJP, Versteeg S, Ryazanov S, Leonov A, Willemen HLDM, Stathonikos N, Seychell RM, El Saghir A, Gerritsen B, Khemtemourian L, Vassallo N, Giese A, Eijkelkamp N, Griesinger C, Höppener JWM Journal BioRxiv Citation bioRxiv 2024.08.27.609850. Abstract Cytotoxic aggregates of human islet amyloid polypeptide (hIAPP)

Authors Rotsch AH, Li D, Dupont M, Krischuns T, Oberthuer C, Stelfox A, Lukarska M, Fianu I, Lidschreiber M, Naffakh N, Dienemann C, Cusack S, Cramer P Journal BioRxiv Citation bioRxiv 2024.08.11.607481. Abstract Influenza virus mRNA is stable and competent for nuclear export and translation because it receives a 5′