Nature Communications

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01.04.2022

Selective optogenetic control of Gq signaling using human Neuropsin

Authors Wagdi A, Malan D, Sathyanarayanan U, Beauchamp JS, Vogt M, Zipf D, Beiert T, Mansuroglu B, Dusend V, Meininghaus M, Schneider L, Kalthof B, Wiegert JS, König GM, Kostenis E, Patejdl R, Sasse P, Bruegmann T Journal Nature Communications Citation Nat Commun. 2022 Apr 1;13(1):1765. Author Correction: Nat Commun.
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28.03.2022

Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system

Authors Calapai A, Cabrera-Moreno J, Moser T, Jeschke M Journal Nature Communications Citation Nat Commun. 2022 Mar 28;13(1):1648. Abstract Devising new and more efficient protocols to analyze the phenotypes of non-human primates, as well as their complex nervous systems, is rapidly becoming of paramount importance. This is because with genome-editing
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04.03.2022

White matter integrity in mice requires continuous myelin synthesis at the inner tongue

Authors Meschkat M, Steyer AM, Weil MT, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Phan NTN, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave KA, Möbius W Journal Nature Communications Citation Nat Commun. 2022 Mar 4;13(1):1163.  Abstract Myelin, the electrically insulating sheath on axons, undergoes dynamic
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11.02.2022

Allosteric control of Ubp6 and the proteasome via a bidirectional switch

Authors Hung KYS, Klumpe S, Eisele MR, Elsasser S, Tian G, Sun S, Moroco JA, Cheng TC, Joshi T, Seibel T, Van Dalen D, Feng XH, Lu Y, Ovaa H, Engen JR, Lee BH, Rudack T, Sakata E, Finley D Journal Nature Communications Citation Nat Commun. 2022 Feb 11;13(1):838. Abstract
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27.01.2022

Structural basis for safe and efficient energy conversion in a respiratory supercomplex

Authors Kao WC, Ortmann de Percin Northumberland C, Cheng TC, Ortiz J, Durand A, von Loeffelholz O, Schilling O, Biniossek ML, Klaholz BP, Hunte C Journal Nature Communications Citation Nat Commun. 2022 Jan 27;13(1):545. Abstract Proton-translocating respiratory complexes assemble into supercomplexes that are proposed to increase the efficiency of energy
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11.01.2022

The RNA methyltransferase METTL8 installs m3C32 modifications in mitochondrial tRNAThr/Ser(UCN) to optimise tRNA structure and translation

Authors Kleiber N, Lemus-Diaz N, Siller C, Heinrichs M, Mai MMQ, Hackert P, Richter-Dennerlein R, Höbartner C, Bohnsack KE, Bohnsack MT Journal Nature Communications Citation Nat Commun 13, 209 (2022). Abstract Modified nucleotides in tRNAs are important determinants of folding, structure and function. Here we identify METTL8 as a mitochondrial
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08.12.2021

Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R

Authors Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, Doeren J, Klöppner S, Cooper BH, Dityatev A, Rizzoli SO Journal Nature Communications Citation Nat Commun. 2021 Dec 8;12(1):7129. Abstract The brain extracellular matrix (ECM) consists of
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11.11.2021

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

Authors Kettwig M, Ternka K, Wendland K, Krüger DM, Zampar S, Schob C, Franz J, Aich A, Winkler A, Sakib MS, Kaurani L, Epple R, Werner HB, Hakroush S, Kitz J, Prinz M, Bartok E, Hartmann G, Schröder S, Rehling P, Henneke M, Boretius S, Alia A, Wirths O, Fischer
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29.09.2021

Mapping protein interactions in the active TOM-TIM23 supercomplex

Authors Gomkale R, Linden A, Neumann P, Schendzielorz AB, Stoldt S, Dybkov O, Kilisch M, Schulz C, Cruz-Zaragoza LD, Schwappach B, Ficner R, Jakobs S, Urlaub H, Rehling P Journal Nature Communications Citation Nat Commun 12, 5715 (2021) Abstract Nuclear-encoded mitochondrial proteins destined for the matrix have to be transported
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23.07.2021

Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors

Authors Cretu C, Gee P, Liu X, Agrawal A, Nguyen TV, Ghosh AK, Cook A, Jurica M, Larsen NA, Pena V Journal Nature Communications Citation Nat Commun. 2021 Jul 23;12(1):4491. Abstract Intron selection during the formation of prespliceosomes is a critical event in pre-mRNA splicing. Chemical modulation of intron selection
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