Epigenetic Regulation of Gene Transcription

Authors Iqbal M, Maroofian R, Çavdarlı B, Riccardi F, Field M, Banka S, Bubshait DK, Li Y, Hertecant J, Baig SM, Dyment D, Efthymiou S, Abdullah U, Makhdoom EUH, Ali Z, Scherf de Almeida T, Molinari F, Mignon-Ravix C, Chabrol B, Antony J, Ades L, Pagnamenta AT, Jackson A, Douzgou

Authors Joppe KDN, Tatenhorst L, Caldi Gomes L, Zhang S, Parvaz M, Carboni E, Roser AE, El DeBakey H, Bähr M, Vogel-Mikuš K, Ip CW, Becker S, Zweckstetter M, Lingor P Journal Journal of Neurochemistry Citation J Neurochem. 2021 Jun 27. Abstract Regional iron accumulation and α-synuclein (α-syn) spreading pathology

Authors Yigit G, Sheffer R, Daana M, Li Y, Kaygusuz E, Mor-Shakad H, Altmüller J, Nürnberg P, Douiev L, Kaulfuss S, Burfeind P, Wollnik B, Brockmann K Journal Journal of Medical Genetics Citation J Med Genet. 2021 Jun 25:jmedgenet-2021-107769. Abstract Background Developmental and epileptic encephalopathies (DEEs) represent a group of

Authors Sokpor G, Kerimoglu C, Nguyen H, Pham L, Rosenbusch J, Wagener R, Nguyen HP, Fischer A, Staiger JF, Tuoc T Journal Frontiers in Molecular Neuroscience Citation Front. Mol. Neurosci., 16 June 2021, 14: 687581. Abstract Radial neuronal migration is a key neurodevelopmental event indispensable for proper cortical laminar organization.

Authors Wang X, Tan Z, Scholand N, Roeloffs V, Uecker M Journal Philosophical Transactions Series A. Mathematical, physical, and engineering sciences Citation Philos Trans A Math Phys Eng Sci. 2021 Jun 28;379(2200):20200196. Abstract Conventional magnetic resonance imaging (MRI) is hampered by long scan times and only qualitative image contrasts that

Authors Ulmke PA, Sakib MS, Ditte P, Sokpor G, Kerimoglu C, Pham L, Xie Y, Mao X, Rosenbusch J, Teichmann U, Nguyen HP, Fischer A, Eichele G, Staiger JF, Tuoc T Journal Stem Cell Reports Citation Stem Cell Reports. 2021 Mar 23:S2213-6711(21)00138-7. Abstract Intermediate progenitor cells (IPCs) are neocortical neuronal

Authors Epple R, Krüger D, Berulava T, Brehm G, Ninov M, Islam R, Köster S, Fischer A Journal Molecular Neurobiology Citation Mol Neurobiol. 2021 Feb 10. Abstract Neurons are highly compartmentalized cells that depend on local protein synthesis. Messenger RNAs (mRNAs) have thus been detected in neuronal dendrites, and more

Authors Sawicka A, Villamil G, Lidschreiber M, Darzacq X, Dugast-Darzacq C, Schwalb B, Cramer P Journal EMBO Journal Citation EMBO J. 2021 Feb 8:e107015. Abstract Eukaryotic RNA polymerase II (Pol II) contains a tail-like, intrinsically disordered carboxy-terminal domain (CTD) comprised of heptad-repeats, that functions in coordination of the transcription cycle

Authors Ulmke PA, Xie Y, Sokpor G, Pham L, Shomroni O, Berulava T, Rosenbusch J, Basu U, Fischer A, Nguyen HP, Staiger JF, Tuoc T Journal Development Citation Development. 2021 Feb 8;148(3):dev188276. Abstract Fine-tuned gene expression is crucial for neurodevelopment. The gene expression program is tightly controlled at different levels,

Authors Sakib MS, Sokpor G, Nguyen HP, Fischer A, Tuoc T Journal Star Protocols Citation STAR Protoc. 2021 Feb 2;2(1):100318. Abstract Cell sorting can be used to purify cell populations for cell type-specific molecular probing. Fluorescence-activated cell sorting (FACS) coupled with high-throughput sequencing affords molecular signature identification for specific cell