2025

Authors Yalçin M, Grande V, Outeiro TF, Relόgio A Journal NPJ Parkinsons Disease Citation NPJ Parkinsons Dis. 2025 Jul 14;11(1):213. Abstract Parkinson’s Disease (PD) is a prevalent neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. This leads to hallmark motor features that include bradykinesia,

Authors Chouaib AA, Chang HF, Khamis OM, Alawar N, Echeverry S, Demeersseman L, Elizarova S, Daniel JA, Tian Q, Lipp P, Fornasiero EF, Valitutti S, Barg S, Pape C, Shaib AH, Becherer U Journal Nature Communications Citation Nat Commun. 2025 Jul 12;16(1):6450. Abstract Activity recognition in live-cell imaging is labor-intensive

Authors Kiszka KA, Dullin C, Steffens H, Koenen T, Rothermel E, Alves F, Gregor C Journal Science Advances Citation Sci Adv. 2025 Jul 11;11(28):eads0463. Abstract The bacterial bioluminescence system can be applied to produce autonomous bioluminescence in mammalian cells. Until now, the system has only been stably inserted into cells

Authors Stoldt S, Maass F, Weber M, Dennerlein S, Ilgen P, Gaertner J, Canfes A, Schweighofer SV, Jans DC, Rehling P, Jakobs S Journal Nature Communications Citation Nat Commun. 2025 Jul 10;16(1):6391. Abstract Mitochondria contain their own DNA (mtDNA) and a dedicated gene expression machinery. As the mitochondrial dimensions are

Authors Amin F, Stone JT, König C, Mancini N, Murakami K, Bidaye SS, Heim MM, Owald D, Majumder U, Grunwald Kadow IC, Pierzchlińska A, Litwin-Kumar A, Barnstedt O, Gerber B Journal BioRxiv Citation bioRxiv 2025.07.07.663268. Abstract It was classically suggested that behaviour can cause emotions (Darwin 1872). For example, smiling

Authors Kloskowski P, Neumann P, Berndt A, Ficner R Journal Acta Crystallographica Section F-Structural Biology Communications Citation Acta Crystallogr F Struct Biol Commun. 2025 Aug 1. Abstract Nucleotide-bound crystal structures of SARS-CoV-2 NSP13 in ADP- and ATP-bound states were resolved to 1.8 and 1.9 Å, respectively. The ADP-bound model captures

Authors Alekseev A, Hunniford V, Zerche M, Jeschke, M, El May F, Vavakou A, Siegenthaler D, Hueser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband M, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T,

Authors Kovalev K, Stetsenko A, Trunk F, Marin E, Haro-Moreno JM, Lamm GHU, Alekseev A, Rodriguez-Valera F, Schneider TR, Wachtveitl J, Guskov A Journal Structure Citation Structure. 2025 Jul 10:S0969-2126(25)00222-9. Abstract Rhodopsins are light-sensitive membrane proteins capturing solar energy via a retinal cofactor covalently attached to a lysine residue. Several

Authors Antonicka H, Vučković A, Weraarpachai W, Hong S, Brischigliaro M, Ahn A, Barrientos A, Hillen HS, Shoubridge EA Journal Nucleic Acids Research Citation Nucleic Acids Res. 2025 Jul 8;53(13):gkaf665. Abstract The first post-transcriptional step in mammalian mitochondrial gene expression, required for the synthesis of the 13 polypeptides encoded in

Authors Lamm GHU, Marin E, Alekseev A, Schellbach AV, Stetsenko A, Haro-Moreno JM, Bourenkov G, Borshchevskiy V, Asido M, Agthe M, Engilberge S, Rose SL, Caramello N, Royant A, Schneider TR, Bateman A, Mager T, Moser T, Rodriguez-Valera F, Wachtveitl J, Guskov A, Kovalev K Journal Science Advances Citation Sci