Biomedical Optics Express

Authors Markus MA, Ferrari DP, Alves F, Ramos-Gomes F Journal Biomedical Optics Express Citation Biomed. Opt. Express 14, 3988-4002 (2023). Abstract Fixation methods such as formalin are commonly used for the preservation of tissue with the aim of keeping their structure as close as possible to the native condition. However,

Authors Wittmeier A, Bernhardt M, Robisch A-L, Cassini C, Osterhoff M, Salditt T, Köster S Journal Biomedical Optics Express Citation Biomed. Opt. Express 13, 4954-4969 (2022) Abstract The function of a biological cell is fundamentally defined by the structural architecture of packaged DNA in the nucleus. Elucidating information about the

Authors Eckermann M, van der Meer F, Cloetens P, Ruhwedel T, Möbius W, Stadelmann C, Salditt T Journal Biomedical Optics Express Citation Biomed. Opt. Express 12, 7582-7598 (2021). Abstract In this work, we optimize the setups and experimental parameters of X-ray phase-contrast computed-tomography for the three-dimensional imaging of the cyto-

Authors Khan A, Ramos-Gomes F, Markus A, Mietsch M, Hinkel R, Alves F Journal Biomedical Optics Express Citation Biomed. Opt. Express 12, 7009-7023 (2021). Abstract Heart failure is one of the most common causes of morbidity and mortality. Both maturational abnormalities and age-associated cardiac pathologies contribute to heart failure. Imaging-based

Authors Mojiri S, Isbaner S, Mühle S, Jang H, Bae AJ, Gregor I, Golami A, Enderlein J Journal Biomedical Optics Express Citation Biomed. Opt. Express 12, 3169-3180 (2021). Abstract High speed volumetric optical microscopy is an important tool for observing rapid processes in living cells or for real-time tracking of

Authors Krüger JR, Keller-Findeisen J, Geisler C, Egner A Journal Biomedical Optics Express Citation Biomed. Opt. Express 11, 3139-3163 (2020). Abstract Stimulated emission depletion (STED) microscopy is a versatile imaging method with diffraction-unlimited resolution. Here, we present a novel STED microscopy variant that achieves either increased resolution at equal laser

Authors Joppe K, Nicolas JD, Grünewald TA, Eckermann M, Salditt T, Lingor P Journal Biomedical Optics Express Citation Biomed. Opt. Express. 2020 11(4). Abstract In this work we use scanning X-ray microscopy to study the structure and elemental composition of neuromelanin-positive neurons in substantia nigra tissue of Parkinson patients (PD) and controls.

Authors Reichardt M, Frohn J, Khan A, Alves F, Salditt T Journal Biomedical Optics Express Citation Biomed Opt Express. 2020 May 1; 11(5): 2633–2651. Abstract The spatial organization of cardiac muscle tissue exhibits a complex structure on multiple length scales, from the sarcomeric unit to the whole organ. Here we