Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis

Authors

Lavdovskaia E, Hillen HS, Richter-Dennerlein R

Journal

Trends in Cell Biology

Citation

Trends Cell Biol. 2021.

Abstract

Final maturation steps during ribo-some biogenesis require the assis-tance of assembly and qualitycontrol factors to ensure the foldingof rRNA and proteins into a func-tional translation machinery. Herewe integrate several recent struc-tural snapshots of native large ribo-somal subunit intermediates intothe complex pathway of mitochon-drial ribosome assembly.

DOI

10.1016/j.tcb.2021.09.004