Depopulation of dense alpha-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model
Authors Wegrzynowicz, M.Bar-On D, Calo L, Anichtchik O, Iovino M, Xia J, Ryazanov S, Leonov A, Giese A, Dalley JW, Griesinger C, Ashery U, Spillantini MG Journal Acta Neuropathologica Citation Acta Neuropathol. 2019 Oct;138(4):575-595. Abstract Parkinson’s disease (PD) is characterized by the presence of α-synuclein aggregates known as Lewy bodies