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Wie Matrix-Recycling das Gehirn flexibel hält
08.12.2021

Wie Matrix-Recycling das Gehirn flexibel hält

Wissenschaftler*innen des Exzellenzclusters Multiscale Bioimaging beschreiben neuen Mechanismus, der zum Erhalt der synaptischen Plastizität im erwachsenen Gehirn beiträgt. Veröffentlicht in Nature Communications. Die extrazelluläre Matrix (EZM) gibt Zellverbänden ihre Struktur und spielt eine wichtige Rolle bei der Kommunikation und Steuerung von Zellen. Im erwachsenen Gehirn bildet sie ein Gitter, das
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Genexpression in Mitochondrien gezielt verändern
23.11.2021

Genexpression in Mitochondrien gezielt verändern

Wissenschaftler*innen des Göttinger Exzellenzclusters Multiscale Bioimaging (MBExC) und des Sonderforschungsbereichs 1190 entwickeln neue Strategie zur Untersuchung der Genexpression in Mitochondrien. Veröffentlicht im Wissenschaftsjournal „Cell“. Mitochondrien gelten als die Kraftwerke der Zellen, da sie mit Hilfe von Sauerstoff Energie aus unserer Nahrung erzeugen. Die dafür notwendige Maschinerie wird als Atmungskette bezeichnet.
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Prof. Dr. Jan Huisken tritt Humboldt-Professur an
08.10.2021

Prof. Dr. Jan Huisken tritt Humboldt-Professur an

Physiker stärkt Forschung am Exzellenzcluster im Bereich Multiskalen-Biologie (mbexc/pug/umg) Der Physiker Prof. Dr. Jan Huisken hat eine Alexander von Humboldt-Professur an der Universität Göttingen angetreten. Seiner Berufung auf diese renommierte Position ging die erfolgreiche Nominierung durch die Universität im November vergangenen Jahres voraus. Als Mitglied des Exzellenzclusters „Multiscale Bioimaging: Von
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MBExC heißt Jun.-Prof. Dr. Nadja Simeth willkommen
01.10.2021

MBExC heißt Jun.-Prof. Dr. Nadja Simeth willkommen

Chemikerin Nadja Simeth tritt Juniorprofessur für Chemie der Molekularen Markierung an der Universität Göttingen an. Die Expertin im Bereich organische Chemie und Photochemie unterstützt zukünftig die Forschung des Exzellenzclusters MBExC. (mbexc) Die Chemikerin Dr. Nadja Simeth erhält eine Juniorprofessur für Chemie der Molekularen Markierung an der Universität Göttingen zum Aufbau
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Revolutionäre Hochleistungsmikroskopie für das Göttinger Exzellenzcluster MBExC
20.05.2021

Revolutionäre Hochleistungsmikroskopie für das Göttinger Exzellenzcluster MBExC

Die Deutsche Forschungsgemeinschaft und das Land Niedersachsen fördern die Anschaffung eines Instrumentariums für Kryo-Elektronenmikroskopie/-tomographie für Forschende um UMG-Professor Dr. Rubén Fernández-Busnadiego am Exzellenzcluster MBExC. Die Instrumente wurden im April angeliefert und in Räumlichkeiten in der Fakultät für Physik der Universität Göttingen aufgestellt. Beschaffung und Umbau wurden mit insgesamt rund 7,3
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Better hearing with optical cochlear implants
27.04.2021

Better hearing with optical cochlear implants

Understanding spoken words, developing normal speech – cochlear implants enable people with profound hearing impairment to gain a great deal in terms of quality of life. However, background noises are problematic, they significantly compromise the comprehension of speech of people with cochlear implants. The team led by Tobias Moser from
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How synapses maintain their activity despite ageing
18.03.2021

How synapses maintain their activity despite ageing

Scientists of the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) and the Collaborative Research Center 1286, University Medical Center Göttingen and Max Planck Institute for Dynamics and Self-Organization uncover a link between protein turnover and synaptic activity. Published in Cell Reports. (mbexc/umg) Synapses, the communication sites between nerve cells, are
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Synaptic diversity broadens the range of sound we can hear
05.02.2021

Synaptic diversity broadens the range of sound we can hear

Hearing occurs when sensory hair cells in the inner ear convert sound into neural signals transmitted to the brain. The sensory hair cells have about a dozen communication points with the auditory nerve fibers, called synapses. Scientists from the Institute for Auditory Neuroscience at the University Medical Center Göttingen discovered
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Jörg Enderlein receives ERC Advanced Grant
12.01.2021

Jörg Enderlein receives ERC Advanced Grant

Physicist Professor and MBExC member Jörg Enderlein receives European Research Council Advanced Grant for his project “Single-molecule, metal-induced energy transfer”. (mbexc/pug) Physicist Professor Jörg Enderlein, PI of the Excellence Cluster “Multiscale Bioimaging” (MBExC), from the University of Göttingen has been awarded an Advanced Grant by the European Research Council (ERC).
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Highly awarded “Scientific Grand prize” of the Fondation Pour l’Audition for Göttingen hearing researcher
18.11.2020

Highly awarded “Scientific Grand prize” of the Fondation Pour l’Audition for Göttingen hearing researcher

Prof. Dr. Tobias Moser receives high distinction from French Fondation Pour l’Audition: “Scientific Grand Prize” 2020 honours his pioneering work on the optical cochlear implant for the treatment of hearing loss. The prize is endowed with 100,000 euros. (mbexc/umg) ) Prof. Dr. Tobias Moser, Director of the Institute for Auditory
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Physicist Dr. Jan Huisken nominated for top level research at the Cluster of Excellence MBExC
17.11.2020

Physicist Dr. Jan Huisken nominated for top level research at the Cluster of Excellence MBExC

Göttingen University receives another Alexander von Humboldt Professorship (mbexc/umg) The University of Göttingen was once again successful in the competition for the most highly endowed German research award: Physicist Dr. Jan Huisken, nominated by the University of Göttingen, has been awarded an Alexander von Humboldt Professorship. The professorship, financed by
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Exhibition „Sinneswelten“ (World of Senses)
09.11.2020

Exhibition „Sinneswelten“ (World of Senses)

Since October 2020, fascinating enlargements of microscope images are presented in the exhibition „Sinneswelten“ (World of Senses) at the University Medical Center Göttingen. The gallery can be visited by patients, students and UMG employees, and is located between the main entrance and the Bettenhaus 1 . Due to the corona
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Two ERC Synergy Grants for Göttingen neuroscientists
06.11.2020

Two ERC Synergy Grants for Göttingen neuroscientists

Two Göttingen researchers receive highly regarded Synergy Grant funding from the European Research Council. More than six million euros of European funding will go to the Göttingen Campus. (mbexc/umg/mpiem) Professors Silvio Rizzoli, Director of the Institute of Neuro- and Sensory Physiology at the University Medical Center Göttingen (UMG), and Nils
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Generation of human brain organoids with the ability to learn
28.08.2020

Generation of human brain organoids with the ability to learn

Stem cell technologies are revolutionizing the biomedical field. Scientists at the University Medical Center Göttingen (UMG) in collaboration with research partners of the Cluster of Excellence “Multiscale Bioimaging” (MBExC) and the German Center for Neurodegenerative Disease (DZNE) combined induced pluripotent stem cells (iPSC) and their deep knowledge in the bioengineering
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New insights into lung tissue in Covid-19 disease
21.08.2020

New insights into lung tissue in Covid-19 disease

Researchers led by Göttingen University develop new three-dimensional imaging technique to visualize tissue damage in severe Covid-19 (pug) Physicists at the University of Göttingen and the Cluster of Excellence “Multiscale Bioimaging” (MBExC), together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique
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CRISPR/Cas9 – GENE EDITING: New therapeutic approach for congenital heart defects
05.08.2020

CRISPR/Cas9 – GENE EDITING: New therapeutic approach for congenital heart defects

Scientists at the Heart Center of the University Medical Center Göttingen have for the first time found an approach for a personalised therapy option with “gene editing” for the Noonan Syndrome. Publication in the renowned journal “Circulation“. (umg/ mbexc) Congenital heart diseases are the most common organ defects. They occur
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In one sweep: Visualization of protein mobility in the synapse
30.07.2020

In one sweep: Visualization of protein mobility in the synapse

(mbexc/umg) All functions of the neural system, including body movements, sensory reactions, and information processing in the brain, depend on the constant and controlled communication between nerve cells. The contact sites between nerve cells, the synapses, have been extensively studied over the last decades, extending our understanding of brain functioning
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On the way to the optical cochlear implant
22.07.2020

On the way to the optical cochlear implant

Interdisciplinary team of scientists from the University Medical Center Göttingen and the University of Freiburg generate for the first time light-controlled behaviour in deaf rodents using optical cochlear implants based on light-emitting diodes. Published in Science Translational Medicine. (mbexc/umg) The cochlear implant (CI) enables worldwide over 700,000 people with profoundly
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