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24.04.2026

Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: Findings from the Rhineland Study

Authors Melas K, Talevi V, Imtiaz MA, Krüger DM, Pena-Centeno T, Fischer A, Aziz NA, Breteler MMB Journal Molecular Psychiatry Citation Mol Psychiatry. 2026 Apr 24. Abstract MicroRNAs (miRNAs) have been linked to brain disorders, but their relations with hippocampal structure and atrophy remain unexplored. As the hippocampus is pivotal
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20.04.2026

Labeling and imaging of neurons with a genetically encoded autonomous bioluminescence system

Authors Brinker T, Günther A, Kiszka KA, Rhee JS, Gregor C Journal Scientific Reports Citation Sci Rep. 2026 Apr 20;16(1):12892. Abstract The bacterial bioluminescence system, consisting of a luciferase and enzymes for intracellular luciferin synthesis, enables autonomous bioluminescence imaging of mammalian cells. Its continuous light emission without the need for
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18.04.2026

The vacuolar tauopathy-associated mutation D395G confers redox sensitivity to p97/VCP

Authors Rout SR, Kulke M, Droemer M, Wendel M, Cheng TC, Mauck TA, Asgari S, Nemec AA, Shein M, Sato Y, Fukai S, Witte G, Tomko Jr. RJ, Stengel F, Zacharias M, Schuetz AK, Sakata E Journal BioRxiv Citation bioRxiv 2026.04.16.718620 Abstract The multifunctional AAA+ ATPase p97/VCP is a pivotal
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16.04.2026

Distributional Convergence of Empirical Entropic Optimal Transport and Statistical Applications

Authors Arenas-Velilla S, Munk A, Rodríguez LA Journal Arxiv Citation arXiv:2604.12940 Abstract Recently, the statistical properties of empirical Entropic Optimal Transport (EOT) have attracted great interest, as this quantity has been shown to be useful for complex data analysis, among other reasons due to its computational efficiency. In several applications,
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16.04.2026

Self-propelled particles driven by light

Authors Fischer J, Jurado A, Betz T Journal Arxiv Citation arXiv:2604.14918 Abstract Recent advances in the field of active soft matter promise a lot. Both, experimental advances and theoretical understanding point towards new material classes in reach, for example self-healing materials that might switch their properties from elastic to solid
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09.04.2026

Models of the human heart for biomedical research: Opportunities and challenges

Authors Streckfuss-Bömeke K, Zelarayán LC, Schnabel RB, Kränkel N, Maack C, Eschenhagen T, Kappler HE, Klingmüller U, Kramann R, Loewe A, Milting H, Molina CE, Panáková D, Podesser BK, Schnieke A, Schröder K, Seidel T, Sossalla S, Zgierski-Johnston C, Zimmermann WH, Rog-Zielinska EA, Kohl P Journal Physiological Reports Citation Physiol
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09.04.2026

Pathogenic desmin variants impair nuclear integrity and drive atrial cardiomyopathy

Authors Su W, van Wijk SW, Kishore P, Huang M, Sultan D, Wijdeveld LFJM, Huiskes FG, Collinet ACT, Voigt N, Liutkute A, Brands M, Kirby T, van der Palen RL, Kurakula K, Ramos KS, Lenz C, Bajema IM, van Spaendonck-Zwarts KY, Brodehl A, Milting H, van Tintelen JP, Brundel BJJM
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09.04.2026

In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation

Authors Du D, Albert L, Weitzel M, Eijsink LE, Cotroneo ER, Marzin D, Opazo F, Simeth NA Journal Angewandte Chemie (International ed. in Engl.) Citation Angew Chem Int Ed Engl. 2026 Apr 9:e6231674. Abstract Simple, efficient transformations of fluorogenic nature that proceed under biocompatible conditions without the formation of byproducts
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07.04.2026

Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies

Authors Sridhar S, Vystrčilová M, Khani MH, Karamanlis D, Schreyer HM, Ramakrishna V, Krüppel S, Zapp SJ, Mietsch M, Ecker AS, Gollisch T Journal PLoS Computational Biology Citation PLoS Comput Biol. 2026 Apr 7;22(4):e1014157. Abstract Retinal ganglion cells, the output neurons of the vertebrate retina, often display nonlinear summation of
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02.04.2026

Mass spectrometric proteome profiling using a deep spectral library reveals homogenization of right and left atrial proteomes in persistent atrial fibrillation patients

Authors Liutkute A, Berrandou TE, Kestel S, Schnelle M, Dschun O, Amedei HA, Neuenroth L, Rytkin E, Kyshynska O, Kensah G, El-Essawi A, Jebran AF, Danner BC, Baraki H, Kutschka I, Bremmer F, Urlaub H, Schmidt C, Bouatia-Naji N, Efimov IR, Brundel BJJM, Lenz C, Voigt N Journal Cardiovascular Research
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