Research Alliance

Authors Zung N, Aravindan N, Boshnakovska A, Valenti R, Preminger N, Jonas F, Yaakov G, Willoughby M, Homberg B, Keller J, Kupervaser M, Dezorella N, Dadosh T, Wolf SG, Itkin M, Malitsky S, Brandis A, Barkai N, Fernandez-Busnadiego R, Reddi A, Rehling P, Rapaport D, Schuldiner M Journal BioRxiv Citation

Authors Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmüller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R Journal Nature Communications Citation Nat Commun 15, 3945 (2024). Abstract Proline-rich antimicrobial peptides (PrAMPs) inhibit bacterial protein biosynthesis by binding to the polypeptide exit tunnel

Authors Bock LV, Igaev M, Grubmüller H Journal Current Opinion in Structural Biology Citation Curr Opin Struct Biol. 2024 May 8;86:102825. Abstract Knowledge of the structure and dynamics of biomolecules is key to understanding the mechanisms underlying their biological functions. Single-particle cryo-electron microscopy (cryo-EM) is a powerful structural biology technique

Authors Hundrieser S, Staudt T, Munk A Journal Annales de l’Institut Henri Poincare (B) Probabilites et statistiques Citation Ann. Inst. H. Poincaré Probab. Statist. 60(2): 824-846. Abstract The empirical optimal transport (OT) cost between two probability measures from random data is a fundamental quantity in transport based data analysis. In

Authors Neumann P, Heidemann JL, Wollenhaupt J, Dickmanns A, Agthe M, Weiss MS, Ficner R Journal Acta Crystallographica.Section D, Structural Biology Citation Acta Crystallogr D Struct Biol. 2024 May 1. Abstract CdaA is the most widespread diadenylate cyclase in many bacterial species, including several multidrug-resistant human pathogens. The enzymatic product

Authors Chen J, Stephan T, Gaedke F, Liu T, Li Y, Schauss A, Chen P, Wulff V, Jakobs S, Jüngst C, Chen Z Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2317703121. Abstract Fluorescence

Authors Keller J, Fernández-Busnadiego R Journal Current Opinion in Cell Biology Citation Curr Opin Cell Biol. 2024 Apr 26;88:102363. Abstract Cryo-electron tomography (cryo-ET) allows high resolution 3D imaging of biological samples in near-native environments. Thus, cryo-ET has become the method of choice to analyze the unperturbed organization of cellular membranes.

Authors Wali R, Xu H, Cheruiyot C, Saleem HN, Janshoff A, Habeck M, Ebert A Journal Biological Chemistry Citation Biol Chem. 2024 Apr 24. Abstract Integration of multiple data sources presents a challenge for accurate prediction of molecular patho-phenotypic features in automated analysis of data from human model systems. Here,

Authors Guan C, Nishi K, Kreis CT, Baeumchen O, Goepfert MC, Schmidt CF Journal BioRxiv Citation bioRxiv 2024.04.18.590050. Abstract Auditory receptors can be motile to actively amplify their mechanical input. Here we describe a novel and different type of motility that, residing in supporting cells, shapes physiological responses of mechanoreceptor

Authors Liutkute A, Prosser BL, Voigt N Journal Cardiovascular Research Citation Cardiovasc Res. 2024 Apr 18:cvae072. Abstract No abstract available DOI 10.1093/cvr/cvae072   Pubmed Link