Mitochondrial Gene Expression

Authors Stephan T, Bruser C, Deckers M, Steyer M, Balzarotti F, Barbot M, Behr TS, Heim G, Hubner W, Ilgen P, Lange F, Pacheu-Grau D, Pape JK, Stoldt S, Huser T, Hell SW, Möbius W, Rehling P, Riedel D, Jakobs S Journal EMBO Journal Citation EMBO J 2020 Jun 22;e104105

Authors Ganapathi M, Argyriou L, Martínez-Azorín F,  Morlot S, Yigit G, Lee TM,  Auber B, von Gise A, Petrey DS, Thiele H, Cyganek L, Sabater-Molina M, Ahimaz P, Cabezas-Herrera J, Sorlí-García M, Zibat A, Siegelin MD, Burfeind P, Buchovecky CM, Hasenfuss G, Honig B, Li Y, Iglesias AD, Wollnik B Journal Human Genetics Citation Hum Genet. 2020 Jun 8. Online ahead of print. Abstract Dilated cardiomyopathy (DCM) belongs to the most frequent forms of cardiomyopathy mainly characterized by

Authors Klatt M, Tameling C, Munk A Journal SIAM Journal on Mathematics of Data Science Citation SIAM Journal on Mathematics of Data Science 2 (2), 419-443. Abstract We derive limit distributions for various empirical regularized optimal transport quantities between probability distributions supported on a finite metric space and show their

Authors Drivas TG, Li D, Nair D, Alaimo JT, Alders M, Altmuller J, Barakat TS, Bebin EM, Bertsch NL, Blackburn PR, Blesson A, Bouman AM, Brockmann K, Brunelle P, Burmeister M, Cooper GM, Denecke J, … Wollnik B, et al. Journal European Journal of Human Genetics Citation Eur J Hum

Authors Hillen HS, Kokic G, Farnung L, Dienemann C, Tegunov D, Cramer P Journal Nature Citation Nature 584, 154–156 (2020). Abstract The new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses an RNA-dependent RNA polymerase (RdRp) for the replication of its genome and the transcription of its genes1-3. Here

Authors Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmuller J, Nurnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, Pauli S Journal Human Genetics Citation Hum Genet. Online ahead of print Abstract We report truncating de novo variants in specific exons of

Authors Jakobs S, Stephan T, Ilgen P, Brüser C Journal Annual Reviews of Biophysics Citation Annu Rev Biophys. 2020 May 6;49:289-308. Abstract Mitochondria are essential for eukaryotic life. These double-membrane organelles often form highly dynamic tubular networks interacting with many cellular structures. Their highly convoluted contiguous inner membrane compartmentalizes the

Authors Linden A, Deckers M, Parfentev I, Pflanz R, Homberg B, Neumann P, Ficner R, Rehling P, Urlaub H Journal Molecular & Cellular Proteomics Citation Mol Cell Proteomics. 2020 Apr 24;mcp.RA120.002028. Abstract Protein cross-linking and the analysis of cross-linked peptides by mass spectrometry is currently receiving much attention. Not only

Authors Wang C, Richter-Dennerlein R, Pacheu-Grau D, Liu F, Zhu Y, Dennerlein S, Rehling P Journal EMBO Reports Citation EMBO Rep. 2020 Jan 7;21(1):e48833. Abstract The mitochondrial genome encodes for thirteen core subunits of the oxidative phosphorylation system. These proteins assemble with imported proteins in a modular manner into stoichiometric

Authors Wang H, Farnung L, Dienemann C, Cramer P Journal Nature Structural & Molecular Biology Citation Nat Struct Mol Biol. 2020 Jan;27(1):8-13. Abstract Recognition of histone-modified nucleosomes by specific reader domains underlies the regulation of chromatin-associated processes. Whereas structural studies revealed how reader domains bind modified histone peptides, it is