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Authors Ganapathi M, Argyriou L, Martínez-Azorín F,  Morlot S, Yigit G, Lee TM,  Auber B, von Gise A, Petrey DS, Thiele H, Cyganek L, Sabater-Molina M, Ahimaz P, Cabezas-Herrera J, Sorlí-García M, Zibat A, Siegelin MD, Burfeind P, Buchovecky CM, Hasenfuss G, Honig B, Li Y, Iglesias AD, Wollnik B Journal Human Genetics Citation Hum Genet. 2020 Jun 8. Online ahead of print. Abstract Dilated cardiomyopathy (DCM) belongs to the most frequent forms of cardiomyopathy mainly characterized by

Authors Stik G, Vidal E, Barrero M, Cuartero S, Vila-Casadesús M, Mendieta-Esteban J, Tian TV, Choi J, Berenguer C, Abad A, Borsari B, le Dily F, Cramer P, Marti-Renom MA, Stadhouders R, Graf T Journal Nature Genetics Citation Nat Genet. 2020 Jul;52(7):655-661. Abstract Three-dimensional organization of the genome is important

Authors Nevskyi O, Tsukanov R, Gregor I, Karedla N, Enderlein J Journal APL Photonics Citation APL Photonics 5, 061302 (2020). Abstract Single-Molecule Localization Microscopy (SMLM) has become one of the most important methods of super-resolution fluorescencemicroscopy. It is based on the precise localization of single molecules in wide-field microscopy images.

Authors Tiburcy M, Meyer T, Liaw NY, Zimmermann WH Journal STAR protocols Citation STAR Protoc. 2020 Jun 3;1(1):100032. Abstract This protocol describes a robust method for the generation of engineered human myocardium (EHM) from pluripotent stem cells (PSCs) in a multi-well plate under defined, serum-free conditions. By parallel culture of

Authors Klatt M, Tameling C, Munk A Journal SIAM Journal on Mathematics of Data Science Citation SIAM Journal on Mathematics of Data Science 2 (2), 419-443. Abstract We derive limit distributions for various empirical regularized optimal transport quantities between probability distributions supported on a finite metric space and show their

Authors Li H, Munk A, Sieling H, Walther G Journal Biometrika Citation Biometrika (2020), 107, 2, pp. 347–364 Abstract The histogram is widely used as a simple, exploratory way of displaying data, but it is usually not clear how to choose the number and size of the bins. We construct

Authors Gerdes C, Waal N, Offner T, Fornasiero EF, Wender N, Verbarg H, Manzini I, Trenkwalder C, Mollenhauer B, Strohäker T, Zweckstetter M, Becker S, Rizzoli SO, Basmanav FB, Opazo F Journal Nature Communications Citation Nat Commun. 2020 Jun 1;11(1):2729. Abstract Aggregation and spreading of α-Synuclein (αSyn) are hallmarks of several neurodegenerative diseases, thus monitoring human αSyn (hαSyn) in animal models or cell cultures is vital for the field. However,

Authors Drivas TG, Li D, Nair D, Alaimo JT, Alders M, Altmuller J, Barakat TS, Bebin EM, Bertsch NL, Blackburn PR, Blesson A, Bouman AM, Brockmann K, Brunelle P, Burmeister M, Cooper GM, Denecke J, … Wollnik B, et al. Journal European Journal of Human Genetics Citation Eur J Hum

Authors Parfentev I, Schilbach S, Cramer P, Urlaub H Journal Journal of Proteomics Citation J Proteomics. 2020 May 30;220:103754. Abstract Cross-linking mass spectrometry (XL-MS) is steadily expanding its range of applications from purified protein complexes to more complex samples like organelles and even entire cells. One main challenge using non-cleavable

Authors Li H, Schwab J, Antholzer S, Haltmeier M Journal Inverse Problems Citation Inverse Problems 36(2020) 065005 (23pp). Abstract Recovering a function or high-dimensional parameter vector from indirect measurements is a central task in various scientific areas. Several methods for solving such inverse problems are well developed and well understood.