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Authors Osman S, Cramer P Journal Annual Review of Cell and Developmental Biology Citation Annu Rev Cell Dev Biol. 2020 Oct 6;36:1-34. Abstract Gene transcription by RNA polymerase II (Pol II) is the first step in the expression of the eukaryotic genome and a focal point for cellular regulation during

Authors Eckermann M, Peruzzi N, Frohn J, Bech M, Englund E, Veress B, Salditt T, Dahlin LB, Ohlsson B Journal Skin Research and Technology Citation Skin Res Technol. 2020 Oct 6. Abstract BACKGROUND: Enteric neuropathy is described in most patients with gastrointestinal dysmotility and may be found together with reduced

Authors Reichardt M, Neuhaus C, Nicolas JD, Bernhardt M, Toischer K, Salditt T Journal Biophysical Journal Citation Biophys J. 2020 Oct 6;119(7):1309-1323. Abstract We present a multi-scale imaging approach to characterize the structure of isolated adult murine cardiomyocytes based on a combination of full-field three-dimensional (3d) coherent x-ray imaging and

Authors Hentrich T, Wassouf Z, Ehrhardt C, Haas E, Mills JD, Aronica E, Outeiro TF, Hübener-Schmid J, Riess O, Casadei N, Schulze-Hentrich JM Journal Aging Citation Aging (Albany NY). 2020 Oct 5;12. Abstract Parkinson’s disease (PD) is an age-dependent neurodegenerative disorder. Besides characteristic motor symptoms, patients suffer from cognitive impairments

Authors Reshetniak S, Fernández-Busnadiego R, Müller M, Rizzoli SO, Tetzlaff C Journal International Journal of Molecular Sciences Citation Int J Mol Sci. 2020 Oct 2;21(19):E7298. Abstract Synapses play a central role for the processing of information in the brain and have been analyzed in countless biochemical, electrophysiological, imaging, and computational

Authors Kleinlogel S, Vogl C, Jeschke M, Neef J, Moser T Journal Physiological Reviews Citation Physiol Rev. 2020 Oct 1;100(4):1467-1525. Abstract Impairments of vision and hearing are highly prevalent conditions limiting the quality of life and presenting a major socioeconomic burden. For a long time, retinal and cochlear disorders have

Authors Imig C, López-Murcia FJ, Maus L, García-Plaza IH, Mortensen LS, Schwark M, Schwarze V, Angibaud J, Nägerl UV, Taschenberger H, Brose N, Cooper BH Journal Neuron Citation Neuron. 2020 Sep 21:S0896-6273(20)30704-2. Abstract Electron microscopy can resolve synapse ultrastructure with nanometer precision, but the capture of time-resolved, activity-dependent synaptic membrane-trafficking

Authors Wang X, Rosenzweig S, Scholand N, Holme HCM, Uecker M Journal Magnetic Resonance in Medicine Citation Magn Reson Med. 2020 Sep 16. Abstract Purpose: To develop a single-shot multi-slice T1 mapping method by combing simultaneous multi-slice (SMS) excitations, single-shot inversion-recovery (IR) radial fast low-angle shot (FLASH), and a nonlinear

Authors Kovács S, Li H, Bühlmann P Journal Journal of the Korean Statistical Society Citation J. Korean Stat. Soc. (2020). Abstract In this discussion, we compare the choice of seeded intervals and that of random intervals for change point segmentation from practical, statistical and computational perspectives. Furthermore, we investigate a

Authors Peruzzi N, Veress B, Dahlin LB, Salditt T, Andersson M, Eckermann M, Frohn J, Robisch AL, Bech M, Ohlsson B Journal Scandinavian Journal of Gastroenterology Citation Scand J Gastroenterol. 2020 Oct;55(10):1261-1267. Abstract Objectives: Light microscopical analysis in two dimensions, combined with immunohistochemistry, is presently the gold standard to describe