2025

Authors Lázaro DF, Amen T, Gerhardt E, Song C, Burns R, Kruse N, Santos PI, Milovanovic D, Höglinger G, Mollenhauer B, Luk KC, Lee VM, Outeiro TF Journal NPJ Parkinsons Disease Citation NPJ Parkinsons Dis. 2025 Nov 20;11(1):326. Abstract Alpha-synuclein (aSyn) is an intrinsically disordered protein involved in phase separation

Authors Von Koeller HF, Schlemmer A, Luther S, Döring Y, Voigt N, Parlitz U   Journal Frontiers in Network Physiology   Citation Front Netw Physiol. 2025 Nov 18;5:1674919.   Abstract Cardiac dynamics is governed by complex electrical wave patterns, with disruptions leading to pathological conditions like atrial or ventricular fibrillation.

Authors Roos L, Meric Diniz A, Koert E, Schilling M, Uhl M, Thirumalai A, Aakhte M, Kusch K, Huisken J, Moser T, Pape C Journal BioRxiv Citation bioRxiv 2025.11.16.688700. Abstract With the emergence of gene and optogenetic therapies targeting deafness, the comprehensive analysis of the molecular anatomy and physiology of

Authors Mimoso T, Korobeinikov A, Stein A, Milovanovic D, Rizzoli SO, Köster S, Reshetniak S Journal BMC Biology Citation BMC Biol. 2025 Nov 14;23(1):340. Abstract Background: The presence and function of microtubules within the synaptic bouton has long been under investigation. In recent years, evidence has accumulated that connects the

Authors Aakhte M, Müller GF, Roos L, Li J, Göpel T, Weiss KR, Diniz AM, Wenzel J, Schwaninger M, Moser T, Huisken J Journal Nature Biotechnology Citation Nat Biotechnol. 2025 Nov 13. Abstract Light-sheet microscopy is ideal for imaging large and cleared tissues, but achieving a high isotropic resolution for

Authors Kapoor R, Kim H, Garlick E, Lima MADRBF, Esch K, Ruhwedel T, Möbius W, Wolf F, Moser T Journal Science Advances Citation Sci. Adv.11,eady4344(2025). Abstract The cochlea encodes sounds into neural signals at the synapses of inner hair cells (IHCs) and spiral ganglion neurons (SGNs) with remarkable fidelity. To

Authors Blümel M, Schneider AC, Neuhaus V, Ehrlich DA, Graetz M, Wibral M, Makkeh A, Priesemann V Journal Arxiv Citation arXiv:2511.02584 Abstract Associative memory, traditionally modeled by Hopfield networks, enables the retrieval of previously stored patterns from partial or noisy cues. Yet, the local computational principles which are required to

Authors Pradhan R, Sakib MS, Kaurani L, Krueger DM, Pena T, Burckhardt S, Schuetz AL, Kronenberg-Verstee D, Delalle I, Sananbenesi F, Fischer A Journal BioRxiv Citation bioRxiv 2025.10.31.685723. Abstract Long non-coding RNAs (lncRNAs) are emerging as key regulators of brain function, but their contribution to microglial aging and neurodegenerative disease

Authors Müller L, Mallick P, Marín-Carballo AB, Dönges P, Kettlitz RJN, Klett-Tammen CJ, Kretzschmar M, Priesemann V, Contreras S Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2025 Nov 4;122(44):e2524944122. Abstract HIV pre-exposure prophylaxis (PrEP) is

Authors Feng R, Spieth L, Liu L, Berghoff S, Franz J, Liu Q, Wang Z, Tiwari V, Vitale S, Frerich S, Florensa S, Junker N, Huber L, Keller M, Müller C, Bracher F, Ge X, Rensen PCN, Kooij G, Hosang L, Chornyi S, Dichgans M, Gokce O, Saher G, Stadelmann