2022

Authors Haupt LP, Rebs S, Maurer W, Hübscher D, Tiburcy M, Pabel S, Maus A, Köhne S, Tappu R, Haas J, Li Y, Sasse A, Santos CCX, Dressel R, Wojnowski L, Bunt G, Möbius W, Shah AM, Meder B, Wollnik B, Sossalla S, Hasenfuss G, Streckfuss-Bömeke K Journal Basic Research

Authors Dankovich TM, Rizzoli SO Journal Frontiers in Synaptic Neuroscience Citation Front Synaptic Neurosci. 2022 Mar 8;14:854956. Abstract In the adult brain, synapses are tightly enwrapped by lattices of the extracellular matrix that consist of extremely long-lived molecules. These lattices are deemed to stabilize synapses, restrict the reorganization of their

Authors Svetlove A, Albers J, Hülsmann S, Markus MA, Zschüntzsch J, Alves F, Dullin C Journal Cells Citation Cells. 2022 Mar 7;11(5):918. Abstract Duchenne muscular dystrophy (DMD) is the most common x-chromosomal inherited dystrophinopathy which leads to progressive muscle weakness and a premature death due to cardiorespiratory dysfunction. The mdx

Authors Meschkat M, Steyer AM, Weil MT, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Phan NTN, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave KA, Möbius W Journal Nature Communications Citation Nat Commun. 2022 Mar 4;13(1):1163.  Abstract Myelin, the electrically insulating sheath on axons, undergoes dynamic

Authors Laubrock K, von Loesch T, Steinmetz M, Lotz J, Frahm J, Uecker M, Unterberg-Buchwald C Journal European Journal of Radiology Open Citation Eur J Radiol Open. 2022 Mar 2;9:100404. Abstract Objectives: Quantitative evaluations of function, volume and mass are fundamental in the diagnostic workup of different cardiovascular diseases and

Authors Haltmeier M, Li H, Munk A Journal Annual Review of Statistics and Its Application Citation Annu. Rev. Stat. Appl. 2022.9:343-372. Abstract We present a unifying view on various statistical estimation techniques including penalization, variational, and thresholding methods. These estimators are analyzed in the context of statistical linear inverse problems

Authors Heinemann F, Munk A, Zemel Y Journal SIAM Journal on Mathematics of Data Science Citation SIAM Journal on Mathematics of Data Science 2022 4:1, 229-259. Abstract We propose a hybrid resampling method to approximate finitely supported Wasserstein barycenters on large-scale datasets, which can be combined with any exact solver.

Authors Kolar MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller H Journal Nucleic Acids Research Citation Nucleic Acids Res. 2022 Feb 28;50(4):2258-2269. Abstract The ribosome is a fundamental biomolecular complex that synthesizes proteins in cells. Nascent proteins emerge from the ribosome through a tunnel, where they may interact

Authors Gönenc II, Elcioglu NH, Martinez Grijalva C, Aras S, Großmann N, Praulich I, Altmüller J, Kaulfuß S, Li Y, Nürnberg P, Burfeind P, Yigit G, Wollnik B Journal Clinical Genetics Citation Clin Genet. 2022 Feb 26. Abstract Bloom syndrome (BS) is an autosomal recessive disorder with characteristic clinical features of

Authors Herwerth M, Kenet S, Schifferer M, Winkler A, Weber M, Snaidero N, Wang M, Lohrberg M, Bennett JL, Stadelmann C, Hemmer B, Misgeld T Journal Brain Citation Brain, 2022;, awac079. Abstract Neuromyelitis optica (NMO) is a chronic neuroinflammatory disease, which primarily targets astrocytes and often results in severe axon