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Authors Maestro-Lopez M, Cheng TC, Muntaner J, Menendez M, Alonso M, Schweitzer A, Ishizaka M, Tomko Jr. RJ, Cuellar J, Valpuesta JM, Sakata E Journal Science Advances Citation Sci Adv. (2025). accepted manuscript. Abstract The 26S proteasome primarily degrades proteins marked by polyubiquitin chains. Although ubiquitin-independent pathways for proteasomal degradation

Authors Svennberg E, Merino JL, Andrade J, Anselmino M, Arbelo E, Boersma E, Boriani G, Breithardt G, Chung M, Chyou J, Cohen A, Nielsen JC, Dichtl W, Diederichsen SZ, Dobrev D, Doehner W, Dworatzek E, Fabritz L, Filgueiras-Rama D, Gimpelewitz C, Hack G, Hatem S, Healey J, Heidbuchel H, Hijazi

Authors Müller L, Sartori F, Dehning J, Eggl MF, Priesemann V Journal Arxiv Citation arXiv:2512.11454. Abstract Mitigation measures are essential for controlling the spread of infectious diseases during pandemics and epidemics, but they impose considerable societal, individual, and economic costs. We developed a general optimization framework to balance costs related

Authors Enderlein J Journal eLight Citation eLight 5, 34 (2025). Abstract Historically constrained by the low throughput of traditional Time-Correlated Single-Photon Counting (TCSPC), a new method utilizes an optimized, time-gated single-photon camera acquisition scheme for achieving single-molecule lifetime precision comparable to TCSPC, but across a wide field of view simultaneously.

Authors Yu B, Sinha M, Mendes Da Silva R, Roelleke U, Burghammer M, Koester S Journal BioRxiv Citation bioRxiv 2025.12.05.692524. Abstract Due to their high penetration depth, X-rays enable us to obtain information from the interior of whole, unsliced cells. Scanning small angle X-ray scattering (SAXS), in particular, reveals real-space

Authors Roos L, Garrido-Charles A, Albrecht N, Vavakou A, Alekseev A, Bleyer M, Thirumalai A, Mittring A, Alvanos T, Huet AT, Bamberg E, Kusch K, Wolf BJ, Moser T, Mager T Journal EMBO Molecular Medicine Citation EMBO Mol Med. 2025 Dec 9. Abstract Optogenetics allows versatile control of excitable cell

Authors Annamalai K, Dilliker S, Buchholz E, Castro-Hernández R, Panyam N, Pommeranz A, Wiederhake P, Wery von Limont N, Hempel N, Ebner V, Swarnkar S, Mohamed BA, Streckfuss-Bömeke K, Steffens S, Herzig S, Ebert A, Fischer A, Toischer K Journal Cell Communication and Signaling Citation Cell Commun Signal. 2025 Dec

Authors Outeiro TF, Koss DJ Journal Movement Disorders Citation Mov Disord. 2025 Nov 26. Abstract Alpha-synuclein (aSyn), historically studied for its synaptic functions and central role in Lewy body pathology, is emerging as a protein with significant nuclear activities relevant to Parkinson’s disease (PD) and related synucleinopathies. Recent advances reveal

Authors Lewen D, Ivanov V, Dehning J, Ruß J, Fischer A, Penke L, Schacht A, Gail A, Priesemann V, Kagan I Journal Communications Psychology Citation Commun Psychol. 2025 Nov 24;3(1):170. Abstract Real-life social interactions often unfold continuously and involve dynamic cooperation and competition, yet most studies rely on discrete games

Authors Stumpf D, Jensen N, Mittelheisser C, Keller-Findeisen J, Chizhik AI, Kamper M, Diekmann T, Habenstein F, Jansen I, Enderlein J, Sliwa M, Inamdar K, Hell SW, Jakobs S Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S