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Authors Maestro-López M, Cheng TC, Muntaner J, Menéndez M, Alonso M, Schweitzer A, Ishizaka M, Tomko RJ Jr, Cuéllar J, Valpuesta JM, Sakata E Journal Science Advances Citation Sci Adv. 2026 Feb 20;12(8):eadz3026. Abstract Coupling between the chaperone and degradation systems, particularly under stress, is essential for eliminating unfolded proteins.

Authors van der Wal JJ, Peshkov RY, Steen JD, Simeth NA, Crespi S Journal Angewandte Chemie (International ed. in Engl.) Citation Angew Chem Int Ed Engl. 2026 Feb 20:e23613. Abstract The mechanism of thermal Z → E isomerization in azobenzenes has been debated for nearly a century, with inversion, rotation,

Authors Richter-Dennerlein R, Dopico XC, Rorbach J Journal Nature Reviews. Molecular Cell Biology Citation Nat Rev Mol Cell Biol. 2026 Feb 13. Abstract Human mitochondrial ribosomes (mitoribosomes) synthesize the 13 mitochondrial-encoded proteins of the oxidative phosphorylation machinery in a coordinated manner, ensuring proper folding of nascent peptides into the inner

Authors Grimm C, Sims RR, Tanese D, Mohamed Lafirdeen AS, Bendifallah I, Chan CY, Faini G, Putti E, Del Bene F, Papagiakoumou E, Emiliani V Journal Neuron Citation Neuron. 2026 Feb 12:S0896-6273(25)00970-5. Abstract Advances in optical techniques and two-photon (2P) sensitive genetic voltage indicators (GEVIs) enabled in-depth voltage imaging at

Authors Cortes Silva JA, Gertig M, Centeno TP, Burkhardt S, Schutz AL, Sananbenesi F, Fischer A Journal BioRxiv Citation bioRxiv 2026.02.08.704661. Abstract Alzheimers disease (AD) displays pronounced regional heterogeneity, yet how transcriptional changes across brain regions converge into coordinated cellular and molecular programs remains unclear. Here, we integrated bulk and

Authors Anders M, Hoppe S, Eberl H, Rebs S, Seedorf A, Maurer W, Schill T, Zibat A, Unsöld JK, Yigit G, Wollnik B, Vollmann D, Sossalla S, Streckfuss-Bömeke K Journal Stem Cell Research Citation Stem Cell Res. 2026 Feb 3;92:103921. Abstract KCNQ1 functions as a slow rectifying potassium channel during

Authors Gallea JI, Karedla N, Wang D, Zhao B, Chen L, Enderlein J, Chen T Journal BioRxiv Citation bioRxiv 2024.09.27.614973. Abstract The dynamic behavior of cellular membranes underpins essential biological processes, including signal transduction, intracellular trafficking, and mechanotransduction. However, simultaneously quantifying lateral molecular diffusion and vertical membrane fluctuations in live

Authors Haertter D, Hauke L, Driehorst T, Nish Ki, Zimmermann W, Schmidt CF Journal BioRxiv Citation bioRxiv 2024.05.28.596183. Abstract Cardiac contraction is driven by the collective action of cardiomyocytes, that contain parallel bundles of myofibrils consisting of linear chains of sarcomeres, the basic force-generating units. The dynamics of individual sarcomeres

Authors Marx D, Gligonov I, Malsbenden D, Wöll D, Nevskyi O, Enderlein J. Journal Nano Letters Citation Nano Lett. 2026 Jan 20. Abstract Single fluorescent molecules, acting as ideal point dipoles, offer a unique means to probe light-matter interactions at the nanoscale. Here, we exploit this property to map the

Authors Häring M, Zhang Y, Zhang N, Allgeyer ES, Richens JH, Sirinakis G, Lv Z, St Johnston D, Wolf F, Großhans J, Kong D Journal Biophysical Journal Citation Biophys J. 2026 Jan 16:S0006-3495(26)00041-X. Abstract Cell junction remodeling is central to epithelial morphogenesis and tissue rheology, and depends on the interplay