Physiological Reviews

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16.06.2023

Physiology of intracellular calcium buffering

Authors Eisner D, Neher E, Taschenberger H, Smith G Journal Physiological Reviews Citation Physiol Rev. 2023 Jun 16. Abstract Calcium signalling underlies much of physiology. Almost all the Ca2+ in the cytoplasm is bound to buffers, with typically only about 1% being freely ionized at resting levels in most cells.
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10.01.2022

The Role of Junctophilin Proteins in Cellular Function

Authors Lehnart SE, Wehrens XHT Journal Physiological Reviews Citation Physiol Rev. 2022 Jan 10. Abstract Junctophilins (JPHs) comprise a family of structural proteins that connect the plasma membrane to intracellular organelles such as the endo/sarcoplasmic reticulum. Tethering of these membrane structures results in the formation of highly organized subcellular junctions
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01.10.2020

Emerging Approaches for Restoration of Hearing and Vision

Authors Kleinlogel S, Vogl C, Jeschke M, Neef J, Moser T Journal Physiological Reviews Citation Physiol Rev. 2020 Oct 1;100(4):1467-1525. Abstract Impairments of vision and hearing are highly prevalent conditions limiting the quality of life and presenting a major socioeconomic burden. For a long time, retinal and cochlear disorders have
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