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28.10.2019

Sharing Data from Molecular Simulations

Authors Abraham M, Apostolov R, Barnoud J, Bauer P, Blau C, Bonvin A, Chavent M, Chodera J, Condic-Jurkic K, Delemotte L, Grubmuller H, Howard RJ, Jordan EJ, Lindahl E, Ollila OHS, Selent J, Smith DGA, Stansfeld PJ, Tiemann JKS, Trellet M, Woods C, Zhmurov A Journal Journal of Chemical Information
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07.10.2019

Dynamic instability of clathrin assembly provides proofreading control for endocytosis

Authors Chen Y, Yong J, Martinez-Sanchez A, Yang Y, Wu Y, De Camilli P, Fernandez-Busnadiego R, Wu M Journal Journal of Cell Biology Citation J Cell Biol. 2019 Oct 7;218(10):3200-3211. Abstract Clathrin-mediated endocytosis depends on the formation of functional clathrin-coated pits that recruit cargos and mediate the uptake of those
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03.10.2019

Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta

Authors Moosa S, Yamamoto GL, Garbes L, Keupp K, Beleza-Meireles A, Moreno CA, Valadares ER, de Sousa SB, Maia S, Saraiva J, Honjo RS, Kim CA, Cabral de Menezes H, Lausch E, Lorini PV, Lamounier A Jr, Carniero TCB, Giunta C, Rohrbach M, Janner M, Semler O, Beleggia F, Li
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01.10.2019

Contrast enhancement for visualizing neuronal cytoarchitecture by propagation-based x-ray phase-contrast tomography

Authors Töpperwien M, Markus A, Alves F, Salditt T Journal NeuroImage Citation Neuroimage. 2019;199:70-80. Abstract Knowledge of the three-dimensional (3d) neuronal cytoarchitecture is an important factor in order to understand the connection between tissue structure and function or to visualize pathological changes in neurodegenerative diseases or tumor development. The gold
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28.08.2019

Organization and regulation of gene transcription

Authors Cramer P Journal Nature Citation Nature. 2019 Sep;573(7772):45-54. Abstract The regulated transcription of genes determines cell identity and function. Recent structural studies have elucidated mechanisms that govern the regulation of transcription by RNA polymerases during the initiation and elongation phases. Microscopy studies have revealed that transcription involves the condensation
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27.08.2019

Live-cell STED nanoscopy of mitochondrial cristae

Authors Stephan T, Roesch A, Riedel D, Jakobs S Journal Scientific Reports Citation Sci Rep. 2019 Aug 27;9(1):12419. Abstract Mitochondria are highly dynamic organelles that exhibit a complex inner architecture. They exhibit a smooth outer membrane and a highly convoluted inner membrane that forms invaginations called cristae. Imaging cristae in
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24.08.2019

Metal-induced energy transfer

Authors Gregor I, Chizhik A, Karedla N, Enderlein J Journal Nanophotonics Citation Nanophotonics, 8(10), 1689-1699. Abstract Since about a decade, metal-induced energy transfer (MIET) has become a tool to measure the distance of fluorophores to a metal-coated surface with nanometer accuracy. The energy transfer from a fluorescent molecule to surface
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20.08.2019

Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation

Authors Alsina KM, Hulsurkar M, Brandenburg S, Kownatzki-Danger D, Lenz C, Urlaub H, Abu-Taha I, Kamler M, Chiang DY, Lahiri SK, Reynolds JO, Quick AP, Scott L Jr, Word TA, Gelves MD, Heck AJR, Li N, Dobrev D, Lehnart SE, Wehrens XHT Journal Circulation Citation Circulation. 2019 Aug 20;140(8):681-693. Abstract
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01.08.2019

Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau

Authors Brendel M, Deussing M, Blume T, Kaiser L, Probst F, Overhoff F, Peters F, von Ungern-Sternberg B, Ryazanov S, Leonov A, Griesinger C, Zwergal A, Levin J, Bartenstein P, Yakushev I, Cumming, P, Boening G, Ziegler S, Herms J, Giese A, Rominger A Journal Alzheimers’s Research and Therapy Citation
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22.07.2019

Molecular contribution function in RESOLFT nanoscopy

Authors Frahm L, Keller-Findeisen J, Alt P, Schnorrenberg S, Del Alamo Ruiz M, Aspelmeier T, Munk A, Jakobs S, Hell SW Journal Optics Express Citation Opt Express. 2019 Jul 22;27(15):21956-21987. Abstract BACKGROUND: The ultimate objective of a microscope of the highest resolution is to map the molecules of interest in
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