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21.10.2024

Visual objects refine head direction coding

Authors Siegenthaler D, Denny H, Skromne Carrasco S, Mayer JL, Peyrache A, Trenholm S, Mace E Journal BioRxiv Citation bioRxiv 2024.10.21.619417. Abstract Animals use visual objects to guide navigation-related behaviors, from hunting prey, to escaping predators, to exploring the world. However, little is known about where visual objects are encoded
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18.10.2024

Mechanism of polyadenylation-independent RNA polymerase II termination

Authors Rengachari S, Hainthaler T, Oberthuer C, Lidschreiber M, Cramer P Journal Nature Structural & Molecular Biology Citation Nat Struct Mol Biol (2024). Abstract The mechanisms underlying the initiation and elongation of RNA polymerase II (Pol II) transcription are well-studied, whereas termination remains poorly understood. Here we analyze the mechanism
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16.10.2024

Addressing SARS-CoV-2 viroporins with antiarrhythmic drugs

Authors Bloothooft M, Voigt N, de Boer TP Journal Europace Citation Europace. 2024 Oct 3;26(10):euae254. Abstract No abstract available. DOI 10.1093/europace/euae254   Pubmed Link
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16.10.2024

Ex vivo imaging reveals the spatiotemporal control of ovulation

Authors Thomas C, Marx TL, Penir SM, Schuh M Journal Nature Cell Biology Citation Nat Cell Biol. 2024 Oct 16. Abstract During ovulation, an egg is released from an ovarian follicle, ready for fertilization. Ovulation occurs inside the body, impeding direct studies of its progression. Therefore, the exact mechanisms that
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14.10.2024

Lead as a toxic environmental toxicant in models of synucleinopathies

Authors Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Geraldes V, Outeiro TF Journal BioRxiv Citation bioRxiv 2024.10.10.617554. Abstract Lead, a toxic heavy metal, is prevalent in various industrial applications, contributing to environmental contamination and significant health concerns. Lead affects various body systems, especially the brain, causing long-lasting cognitive and
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10.10.2024

Direct optical measuerement of intramolecular distances with angstrom precision

Authors Sahl SJ, Matthias J, Inamdar K, Weber M, Khan TA, Brüser C, Jakobs S, Becker S, Griesinger C, Broichhagen J, Hell SW Journal Science Citation Science. 2024 Oct 11;386(6718):180-187. Abstract Optical investigations of nanometer distances between proteins, their subunits, or other biomolecules have been the exclusive prerogative of Förster
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10.10.2024

NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals

Authors Mougios N, Cotroneo ER, Imse N, Setzke J, Rizzoli S, Simeth NA, Tsukanov R, Opazo F Journal Nature Communications Citation Nat Commun. 2024 Oct 10;15(1):8771. Abstract Fluorescence microscopy has long been a transformative technique in biological sciences. Nevertheless, most implementations are limited to a few targets, which have been
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09.10.2024

One-step nanoscale expansion microscopy reveals individual protein shapes

Authors Shaib AH, Chouaib AA, Chowdhury R, Altendorf J, Mihaylov D, Zhang C, Krah D, Imani V, Spencer RKW, Georgiev SV, Mougios N, Monga M, Reshetniak S, Mimoso T, Chen H, Fatehbasharzad P, Crzan D, Saal KA, Alawieh MM, Alawar N, Eilts J, Kang J, Soleimani A, Müller M, Pape
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08.10.2024

Cardiac arrhythmias: the growing role of autoantibodies in diagnosis and treatment

Authors Fakuade FE, Grune J, Voigt N Journal European Heart Journal Citation Eur Heart J. 2024 Oct 8:ehae648. Abstract No abstract available. DOI 10.1093/eurheartj/ehae648   Pubmed Link
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05.10.2024

The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling
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