Journal

Authors Mücher B, Garrido-Charles A, Cyganek L, Bruegmann T, Dalkara D, Siveke I, Herlitze S Journal BioRxiv Citation bioRxiv 2025.02.06.636923. Abstract Activation of G protein coupled receptors coupling to the Gi/o pathway leads to the activation of G protein-activated inward rectifier potassium channels (GIRK) in a fast membrane-delimited manner in

Authors Chakraborty S, Martinez-Sanchez A, Beck F, Toro-Nahuelpan M, Hwang IY, Noh KM, Baumeister W, Mahamid J Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2025 Feb 4;122(5):e2404017121. Abstract The functional architecture of the long-lived neuronal

Authors Oborská-Oplová M, Geiger AG, Michel E, Klingauf-Nerurkar P, Dennerlein S, Bykov YS, Amodeo S, Schneider A, Schuldiner M, Rehling P, Panse VG Journal Nature Cell Biology Citation Nat Cell Biol. 2025 Jan 31. Abstract The correct sorting of nascent ribosomal proteins from the cytoplasm to the nucleus or to

Authors Basak S, Tsukanov R Journal Methods in Microscopy Citation Methods in Microscopy, 2025. Abstract In this review paper, we summarize the significant advancements in the field of fluorescence lifetime imaging microscopy (FLIM), particularly wide-field FLIM with single-molecule sensitivity, achieved using the time-correlated single-photon counting-based position-sensitive LINCam system. Fluorescence lifetime

Authors Jebran AF, Seidler T, Tiburcy M, Daskalaki M, Kutschka I, Fujita B, Ensminger S, Bremmer F, Moussavi A, Yang H, Qin X, Mißbach S, Drummer C, Baraki H, Boretius S, Hasenauer C, Nette T, Kowallick J, Ritter CO, Lotz J, Didié M, Mietsch M, Meyer T, Kensah G, Krüger

Authors Revah O, Wolf F, Gutnick MJ, Neef A Journal Biorxiv Citation bioRxiv 2024.02.15.580451. Abstract Cortical function reflects the activities of populations of neurons. How accurately they can encode information depends on the speed with which each neuron can respond to input, as revealed by dynamic gain analysis. Theory predicts

Authors Meissner-Bernard C, Jenkins B, Rupprecht P, Bouldoires EA, Zenke F, Friedrich RW, Frank T Journal Cell Reports Citation Cell Reports 44, 115330, March 25, 2025. Abstract Models of balanced autoassociative memory networks predict that specific inhibition is critical to store information in connectivity. To explore these predictions, we characterized

Authors Cretu C, Chernev A, Szabo CZK, Pena V, Urlaub H, Moser T, Preobraschenski J Journal BioRxiv Citation bioRxiv 2025.01.25.634844. Abstract Ferlins, ancient membrane proteins with a unique architecture, are central to multiple essential, Ca2+-dependent vesicle fusion processes. Despite numerous functional studies and their link to burdening human diseases, a

Authors Karagulyan N, Thirumalai A, Michanski S, Qi Y, Fang Q, Wang H, Ortner NJ, Striessnig J, Strenzke N, Wichmann C, Hua Y, Moser T Journal BioRxiv Citation bioRxiv 2025.01.23.634330. Abstract Our sense of hearing processes sound intensities spanning six orders of magnitude. In the ear, postsynaptic spiral ganglion neurons

Authors Eskandari MA, Fischer J, Veyret N, Marx D, Betz T Journal Arxiv Citation arXiv:2501.14538. Abstract While mechanobiology has demonstrated that precise control over mechanical properties at the whole-cell level is crucial for many biological functions, comparatively little attention has been paid to the intracellular mechanical properties. Experimental tools have