Nature Cell Biology

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31.01.2025

An avoidance segment resolves a lethal nuclear-mitochondrial targeting conflict during ribosome assembly

Authors Oborská-Oplová M, Geiger AG, Michel E, Klingauf-Nerurkar P, Dennerlein S, Bykov YS, Amodeo S, Schneider A, Schuldiner M, Rehling P, Panse VG Journal Nature Cell Biology Citation Nat Cell Biol. 2025 Jan 31. Abstract The correct sorting of nascent ribosomal proteins from the cytoplasm to the nucleus or to
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01.12.2024

In-situ architecture of the human prohibitin complex

Authors Lange F, Ratz M, Dohrke JN, Wenzel D, Ilgen P, Riedel D, Jakobs S Journal Nature Cell Biology Citation Nature Cell Biology. accepted manuscript. Abstract Prohibitins are a highly conserved family of proteins that have been implicated in a variety of functions including mitochondrial stress signalling and housekeeping, cell
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16.10.2024

Ex vivo imaging reveals the spatiotemporal control of ovulation

Authors Thomas C, Marx TL, Penir SM, Schuh M Journal Nature Cell Biology Citation Nat Cell Biol. 2024 Oct 16. Abstract During ovulation, an egg is released from an ovarian follicle, ready for fertilization. Ovulation occurs inside the body, impeding direct studies of its progression. Therefore, the exact mechanisms that
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20.06.2024

The maintenance of oocytes in the mammalian ovary involves extreme protein longevity

Authors Harasimov K, Gorry RL, Welp LM, Penir SM, Horokhovskyi Y, Cheng S, Takaoka K, Stützer A, Frombach AS, Taylor Tavares AL, Raabe M, Haag S, Saha D, Grewe K, Schipper V, Rizzoli SO, Urlaub H, Liepe J, Schuh M Journal Nature Cell Biology Citation Nat Cell Biol. 2024 Jun
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02.02.2023

Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes

Authors Harasimov K, Uraji J, Mönnich EU, Holubcová Z, Elder K, Blayney M, Schuh M Journal Nature Cell Biology Citation Nat Cell Biol. 2023 Feb 2. Abstract Accurate chromosome segregation during meiosis is crucial for reproduction. Human and porcine oocytes transiently cluster their chromosomes before the onset of spindle assembly
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