Acta Crystallographica Section D

Authors Kloskowski P, Neumann P, Kumar P, Berndt A, Dobbelstein M, Ficner R Journal Acta Crystallographica Section D-Structural Biology Citation Acta Crystallogr D Struct Biol. 2025 Jun 1. Abstract The SARS-CoV-2 helicase NSP13 is a highly conserved and essential component of the viral replication machinery, making it a promising target

Authors Neumann P, Heidemann JL, Wollenhaupt J, Dickmanns A, Agthe M, Weiss MS, Ficner R Journal Acta Crystallographica.Section D, Structural Biology Citation Acta Crystallogr D Struct Biol. 2024 May 1. Abstract CdaA is the most widespread diadenylate cyclase in many bacterial species, including several multidrug-resistant human pathogens. The enzymatic product

Authors Hamann F, Zimmerningkat LC, Becker RA, Garbers TB, Neumann P, Hubc JS, Ficner R Journal Acta Crystallographica Section D-Structural Biology Citation Acta Cryst. (2021). D77, 496-509. Abstract Noncoding intron sequences present in precursor mRNAs need to be removed prior to translation, and they are excised via the spliceosome, a