Salditt, Tim

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18.03.2020

Multi-Scale X-Ray Phase-Contrast Tomography Of Murine Heart Tissue

Authors Reichardt M, Frohn J, Khan A, Alves F, Salditt T Journal Biomedical Optics Express Citation Biomed Opt Express. 2020 May 1; 11(5): 2633–2651. Abstract The spatial organization of cardiac muscle tissue exhibits a complex structure on multiple length scales, from the sarcomeric unit to the whole organ. Here we
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04.03.2020

Fiber orientation in a whole mouse heart reconstructed by laboratory phase-contrast micro-CT

Authors Reichardt M, Topperwien M, Khan A, Alves F, Salditt T Journal Journal of Medical Imaging Citation J Med Imaging (Bellingham). 2020 Mar;7(2):023501. Abstract Purpose: We present a phase-contrast x-ray tomography study of wild type C57BL/6 mouse hearts as a nondestructive approach to the microanatomy on the scale of the
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06.02.2020

Nanoscale x-ray holotomography of human brain tissue with phase retrieval based on multienergy recordings

Authors Robisch AL, Eckermann M, Topperwien M, van der Meer F, Stadelmann C, Salditt T Journal Journal of Medical Imaging Citation J Med Imaging (Bellingham) 2020 Jan;7(1). Abstract X-ray cone-beam holotomography of unstained tissue from the human central nervous system reveals details down to subcellular length scales. This visualization of
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11.01.2020

Correlative x-ray phase-contrast tomography and histology of human braintissue affected by Alzheimer’s disease

Authors Töpperwien M, van der Meer F, Stadelmann-Nessler C, Salditt T Journal NeuroImage Citation Neuroimage 2020 Apr 15;210:116523. Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder which is characterized by increasing dementia. It isaccompanied by the development of extracellularβ-amyloid plaques and neurofibrillary tangles in the gray matterof the brain. Histology
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06.01.2020

Phase-contrast x-ray tomography of neuronal tissue at laboratory sources with submicron resolution

Authors Eckermann M, Topperwien M, Robisch AL, van der Meer F, Stadelmann C, Salditt T Journal Journal of Medical Imaging Citation J Med Imaging (Bellingham). 2020 Apr 30;124(17):3482-3493. Abstract Purpose: Recently, progress has been achieved in implementing phase-contrast tomography of soft biological tissues at laboratory sources. This opens up opportunities
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01.10.2019

Contrast enhancement for visualizing neuronal cytoarchitecture by propagation-based x-ray phase-contrast tomography

Authors Töpperwien M, Markus A, Alves F, Salditt T Journal NeuroImage Citation Neuroimage. 2019;199:70-80. Abstract Knowledge of the three-dimensional (3d) neuronal cytoarchitecture is an important factor in order to understand the connection between tissue structure and function or to visualize pathological changes in neurodegenerative diseases or tumor development. The gold
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