Salditt, Tim

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25.01.2024

Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations

Authors Alfken J, Neuhaus C, Major A, Taskina A, Hoffmann C, Ganzella M, Petrovic A, Zwicker D, Fernández-Busnadiego R, Jahn R, Milovanovic D, Salditt T Journal European Physical Journey. E, Soft Matter Citation Eur Phys J E Soft Matter. 2024 Jan 25;47(1):8. Abstract We study the formation of vesicle condensates
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02.11.2023

Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs

Authors Shi R, Reichardt M, Fiegle DJ, Küpfer LK, Czajka T, Sun Z, Salditt T, Dendorfer A, Seidel T, Bruegmann T Journal Cardiovascular Research Citation Cardiovasc Res. 2023 Nov 2:cvad141. Abstract Aims: Cardiotoxicity is one major reason why drugs do not enter or are withdrawn from the market. Thus, approaches
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25.09.2023

Imaging of excised cochleae by micro-CT: staining, liquid embedding, and image modalities

Authors Schaeper JJ, Liberman MC, Salditt T Journal Journal of Medical Imaging Citation J. Med. Imag. 10(5) 053501 (25 September 2023) Abstract Purpose: Assessing the complex three-dimensional (3D) structure of the cochlea is crucial to understanding the fundamental aspects of signal transduction in the inner ear and is a prerequisite
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11.05.2023

Human lung virtual histology by multi-scale x-ray phase-contrast computed tomography

Authors Reichmann J, Verleden SE, Kühnel M, Kamp JC, Werlein C, Neubert L, Müller JH, Bui TQ, Ackermann M, Jonigk D, Salditt T Journal Physics in Medicine and Biology Citation Phys Med Biol. 2023 May 11. Abstract As the central organ of the respiratory system, the human lung is responsible
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02.05.2023

Three-dimensional analysis of human pancreatic cancer specimens by phase-contrast based X-ray tomography – the next dimension of diagnosis

Authors Pinkert-Leetsch D, Frohn J, Ströbel P, Alves F, Salditt T, Missbach-Guentner J Journal Cancer Imaging Citation Cancer Imaging. 2023 May 2;23(1):43. Abstract Background: The worldwide increase of pancreatic ductal adenocarcinoma (PDAC), which still has one of the lowest survival rates, requires novel imaging tools to improve early detection and
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13.04.2023

3d virtual histology reveals pathological alterations of cerebellar granule cells in multiple sclerosis

Authors Frost J, Schmitzer B, Töpperwien M, Eckermann M, Franz J, Stadelmann C, Salditt T Journal Neuroscience Citation Neuroscience. 2023 Apr 13:S0306-4522(23)00161-6. Abstract We investigate structural properties of neurons in the granular layer of human cerebellum with respect to their involvement in multiple sclerosis (MS). To this end we analyze
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22.12.2022

On the Fabrication and Characterization of Polymer-Based Waveguide Probes for Use in Future Optical Cochlear Implants

Authors Helke C, Reinhardt M, Arnold M, Schwenzer F, Haase M, Wachs M, Goßler C, Götz J, Keppeler D, Wolf B, Schaeper J, Salditt T, Moser T, Schwarz UT, Reuter D Journal Materials (Basel) Citation Materials (Basel). 2022 Dec 22;16(1):106. Abstract Improved hearing restoration by cochlear implants (CI) is expected
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12.11.2022

Inflammation and vascular remodeling in COVID-19 hearts

Authors Werlein C, Ackermann M, Stark H, Shah HR, Tzankov A, Haslbauer JD, von Stillfried S, Bülow RD, El-Armouche A, Kuenzel S, Robertus JL, Reichardt M, Haverich A, Höfer A, Neubert L, Plucinski E, Braubach P, Verleden S, Salditt T, Marx N, Welte T, Bauersachs J, Kreipe HH, Mentzer SJ,
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25.08.2022

Combined optical fluorescence microscopy and X-ray tomography reveals substructures in cell nuclei in 3D

Authors Wittmeier A, Bernhardt M, Robisch A-L, Cassini C, Osterhoff M, Salditt T, Köster S Journal Biomedical Optics Express Citation Biomed. Opt. Express 13, 4954-4969 (2022) Abstract The function of a biological cell is fundamentally defined by the structural architecture of packaged DNA in the nucleus. Elucidating information about the
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07.08.2022

Structure of the myenteric plexus in normal and diseased human ileum analyzed by X-ray virtual histology slices

Authors Veress B, Peruzzi N, Eckermann M, Frohn J, Salditt T, Bech M, Ohlsson B Journal World Journal of Gastroenterology Citation World J Gastroenterol. Aug 7, 2022; 28(29): 3994-4006. Abstract Background: The enteric nervous system (ENS) is situated along the entire gastrointestinal tract and is divided into myenteric and submucosal
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