Priesemann, Viola

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17.11.2023

Prediction mismatch responses arise as corrections of a predictive spiking code

Authors van Driel K, Rudelt L, Priesemann V, Mikulasch FA Journal Biorxiv Citation bioRxiv 2023.11.16.567335. Abstract Prediction mismatch responses in cortex seem to signal the difference between an internal model of the animal and sensory observations. Often these responses are interpreted as evidence for the existence of error neurons, which
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03.06.2023

Infomorphic networks: Locally learning neural networks derived from partial information decomposition

Authors Graetz M, Makkeh A, Schneider AC, Ehrlich DA, Priesemann V, Wibral M Journal Arxiv Citation arXiv:2306.02149. Abstract Understanding the intricate cooperation among individual neurons in performing complex tasks remains a challenge to this date. In this paper, we propose a novel type of model neuron that emulates the functional
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18.05.2023

A Measure of the Complexity of Neural Representations based on Partial Information Decomposition

Authors Ehrlich DA, Schneider AC, Priesemann V, Wibral M, Makkeh A Journal Transactions on Machine Learning Research Citation Transactions on Machine Learning Research (2023). Abstract In neural networks, task-relevant information is represented jointly by groups of neurons. However, the specific way in which this mutual information about the classification label
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29.11.2022

Sampling effects and measurement overlap can bias the inference of neuronal avalanches

Authors Pinheiro Neto J, Spitzner FP, Priesemann V Journal PLoS Computational Biology Citation PLoS Comput Biol 18(11): e1010678. Abstract To date, it is still impossible to sample the entire mammalian brain with single-neuron precision. This forces one to either use spikes (focusing on few neurons) or to use coarse-sampled activity
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03.05.2022

α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals

Authors Leite K, Garg P, Spitzner FP, Guerin Darvas S, Bähr M, Priesemann V, Kügler S Journal Frontiers in Molecular Neuroscience Citation Front Mol Neurosci. 2022 May 3;15:868790. Abstract α-synuclein (α-Syn) is intimately linked to synucleinopathies like Parkinson’s disease and dementia with Lewy bodies. However, the pathophysiological mechanisms that are
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16.03.2021

Presynaptic activity and protein turnover are correlated at the single-synapse level

Authors Jähne S, Mikulasch F, Heuer HGH, Truckenbrodt S, Agüi-Gonzalez P, Grewe K, Vogts A, Rizzoli SO, Priesemann V Journal Cell Reports Citation Cell Reports 34, 108841, March 16, 2021. Abstract Synaptic transmission relies on the continual exocytosis and recycling of synaptic vesicles. Aged vesicle proteins are prevented from recycling
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