Cyganek, Lukas

Authors Gaubert M, Alachram H, Gönenç II, Domínguez I, Argyriou C, Schmidt J, Kaulfuß S, Pavez-Giani M, Schott CT, Munk A, Zibat A, Cyganek L, Yigit G, Wollnik B Journal BioRxiv Citation bioRxiv 2026.08.18.745450. Abstract The human heart has a continuous and exceptionally high demand for energy, which is met

Authors Fell J, Pavez-Giani M, Koitka F, Kensah G, Santos GL, van der Vorst EPC, Lenz C, Salinas G, Busley AV, Fedorenko A, Hindmarsh R, Wolf CM, Lutz S, Hasenfuss G, Zimmermann WH, Wollnik B, Cyganek L Journal Circulation Citation Circulation. 2026 Apr 16. Abstract Background: Genetic variants in components

Authors Hofhuis J, Tiburcy M, Hartmann Y, Bersch K, Wagdi A, Gutiérrez-Gutiérrez O, Solano R, Thiele L, Walper M, Göbel M, Hübner W, Berecic B, Casini M, Tirilomis P, Unger A, Lipstein N, Sossalla S, Huser T, Streckfuss-Bömeke K, Elkenani M, Toischer K, Kohlhaas M, Dudek J, Zimmermann WH, Voigt

Authors Alekseev A, Hunniford V, Zerche M, Jeschke M, El May F, Vavakou A, Siegenthaler D, Hüser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband MD, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T,

Authors Bögershausen N, Cavdarli B, Nagai TH, Milev MP, Wolff A, Mehranfar M, Schmidt J, Choudhary D, Gutiérrez-Gutiérrez Ó, Cyganek L, Saint-Dic D, Zibat A, Köhrer K, Wollenweber TE, Wieczorek D, Altmüller J, Borodina T, Kaçar D, Haliloğlu G, Li Y, Thiel C, Sacher M, Knapik EW, Yigit G, Wollnik

Authors Haertter D, Hauke L, Driehorst T, Nishi K, Long J, Tiburcy M, Berecic B, Primeßnig A, Bao G, Cyganek L, Schmidt CF, Zimmermann WH Journal BioRxiv Citation bioRxiv 2025.04.29.650605. Abstract Cardiomyocyte function critically depends on sarcomere dynamics and their organization in myofibrils. To uncover how cardiomyocyte function emerges from

Authors Gönenc II, Wolff A, Busley AV, Wieland A, Tijhuis A, Müller C, Wardenaar R, Argyriou L, Kaulfuß S, Räschle M, Spierings DCJ, Foijer F, Bastians H, Yigit G, Zibat A, Cyganek L, Wollnik B Journal BioRxiv Citation bioRxiv 2025.04.17.649287. Abstract Biallelic loss-of-function (LoF) variants in the BTRR complex members

Authors Mücher B, Garrido-Charles A, Cyganek L, Bruegmann T, Dalkara D, Siveke I, Herlitze S Journal BioRxiv Citation bioRxiv 2025.02.06.636923. Abstract Activation of G protein coupled receptors coupling to the Gi/o pathway leads to the activation of G protein-activated inward rectifier potassium channels (GIRK) in a fast membrane-delimited manner in

Authors Busley AV, Gutiérrez-Gutiérrez Ó, Hammer E, Koitka F, Mirzaiebadizi A, Steinegger M, Pape C, Böhmer L, Schroeder H, Kleinsorge M, Engler M, Cirstea IC, Gremer L, Willbold D, Altmüller J, Marbach F, Hasenfuss G, Zimmermann WH, Ahmadian MR, Wollnik B, Cyganek L Journal Cell Reports Citation Cell Rep. 2024

Authors Dobner J, Nguyen T, Pavez-Giani MG, Cyganek L, Distelmaier F, Krutmann J, Prigione A, Rossi A Journal Molecular Therapy: Methods & Clinical Development Citation Mol Ther Methods Clin Dev. 2024 Mar 12;32(2):101231. Abstract Mitochondrial DNA (mtDNA) analysis is crucial for the diagnosis of mitochondrial disorders, forensic investigations, and basic