Cyganek, Lukas

Authors Mücher B, Garrido-Charles A, Wietek J, Köhler I, Grömmke M, Frischmuth T, Cyganek L, Rost BR, Bruegmann T, Schmitz D, Dalkara D, Wahle P, Siveke I, Herlitze S Journal Science Signaling Citation Sci Signal. 2026 Oct 20;19(960):eadw4374. Abstract Stimulation of G protein-coupled receptors (GPCRs) that couple to Gi/o leads

Authors Palacios-Contreras E, an der Brugge K, Fell J, Stephan T, Amedei H, Lenz C, Pesek J, Taudte VR, Lange F, Jakobs S, Sossalla S, Zelarayan LC, Cabrera-Orefice A, Cyganek L, Pavez-Giani MG Journal BioRxiv Citation bioRxiv 2026.09.14.751384. Abstract TMEM70 variants represent the most common nuclear cause of mitochondrial ATP

Authors Bögershausen N, Yigit G, Fedorenko A, Bayati R, Döring P, Gerhardt M, Strohmeyer C, Gutiérrez-Gutiérrez O, Javanmardi B, Gaubert M, Kaygusuz E, Krawitz P, Ueffing M, Hoerauf H, Feltgen N, Michalakis S, Büning H, Cyganek L, Wollnik B Journal Human Gene Therapy Citation Hum Gene Ther. 2026 Sep 14:10430342261480906.

Authors Gaubert M, Alachram H, Gönenç II, Domínguez I, Argyriou C, Schmidt J, Kaulfuß S, Pavez-Giani M, Schott CT, Munk A, Zibat A, Cyganek L, Yigit G, Wollnik B Journal BioRxiv Citation bioRxiv 2026.08.18.745450. Abstract The human heart has a continuous and exceptionally high demand for energy, which is met

Authors Fell J, Pavez-Giani M, Koitka F, Kensah G, Santos GL, van der Vorst EPC, Lenz C, Salinas G, Busley AV, Fedorenko A, Hindmarsh R, Wolf CM, Lutz S, Hasenfuss G, Zimmermann WH, Wollnik B, Cyganek L Journal Circulation Citation Circulation. 2026 Apr 16. Abstract Background: Genetic variants in components

Authors Hofhuis J, Tiburcy M, Hartmann Y, Bersch K, Wagdi A, Gutiérrez-Gutiérrez O, Solano R, Thiele L, Walper M, Göbel M, Hübner W, Berecic B, Casini M, Tirilomis P, Unger A, Lipstein N, Sossalla S, Huser T, Streckfuss-Bömeke K, Elkenani M, Toischer K, Kohlhaas M, Dudek J, Zimmermann WH, Voigt

Authors Alekseev A, Hunniford V, Zerche M, Jeschke M, El May F, Vavakou A, Siegenthaler D, Hüser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband MD, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T,

Authors Bögershausen N, Cavdarli B, Nagai TH, Milev MP, Wolff A, Mehranfar M, Schmidt J, Choudhary D, Gutiérrez-Gutiérrez Ó, Cyganek L, Saint-Dic D, Zibat A, Köhrer K, Wollenweber TE, Wieczorek D, Altmüller J, Borodina T, Kaçar D, Haliloğlu G, Li Y, Thiel C, Sacher M, Knapik EW, Yigit G, Wollnik

Authors Haertter D, Hauke L, Driehorst T, Nishi K, Long J, Tiburcy M, Berecic B, Primeßnig A, Bao G, Cyganek L, Schmidt CF, Zimmermann WH Journal BioRxiv Citation bioRxiv 2025.04.29.650605. Abstract Cardiomyocyte function critically depends on sarcomere dynamics and their organization in myofibrils. To uncover how cardiomyocyte function emerges from

Authors Gönenc II, Wolff A, Busley AV, Wieland A, Tijhuis A, Müller C, Wardenaar R, Argyriou L, Kaulfuß S, Räschle M, Spierings DCJ, Foijer F, Bastians H, Yigit G, Zibat A, Cyganek L, Wollnik B Journal BioRxiv Citation bioRxiv 2025.04.17.649287. Abstract Biallelic loss-of-function (LoF) variants in the BTRR complex members