2026

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26.08.2026

Molecular basis for a Ca2+ binding hierarchy in the EF-hand motifs of CaBP2

Authors Motosugi R, Walinda E, Kim T, Mateias AL, Pallinger T, Prajapati S, Morimoto D, Kim M, Rankovic V, Griesinger C, Tittmann K, Pangrsic T, Sakata E Journal Journal of Biological Chemistry Citation J Biol Chem. 2026 Aug 26:113492. Abstract Calcium binding protein 2 (CaBP2), a member of the calmodulin
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26.08.2026

Systematic Review and Transcriptomic Meta-analysis of Environmental Enrichment Reveal Core Molecular Programs of Brain Plasticity

Authors Kurowska M, Miozzo F, Schroeder R, Machnicka MA, Pérez-González R, Merienne K, Fischer A, Barco A, Boutillier AL, Wilczyński B Journal Molecular Neurobiology Citation Mol Neurobiol. 2026 Aug 26;63(1):857. Abstract Environmental enrichment (EE) paradigms in rodents have long demonstrated that enhanced sensory, cognitive, social, and motor stimulation positively impacts
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26.08.2026

In silico framework for benchmarking optogenetic hearing restoration

Authors Khurana L, Nejedly P, Zhang Y, Jagger DJ, Nogueira W, Moser T, Jablonski L Journal Journal of Neural Engineering Citation J Neural Eng. 2026 Aug 26. Abstract Objective: Cochlear implants (CI) partially restore hearing in profoundly hearing-impaired or deaf individuals by electrically stimulating the auditory nerve. A primary bottleneck
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22.08.2026

Distinct mitochondrial DNA single-nucleotide variant signatures in TOP3A-deficient cardiomyocytes

Authors Gaubert M, Alachram H, Gönenç II, Domínguez I, Argyriou C, Schmidt J, Kaulfuß S, Pavez-Giani M, Schott CT, Munk A, Zibat A, Cyganek L, Yigit G, Wollnik B Journal BioRxiv Citation bioRxiv 2026.08.18.745450. Abstract The human heart has a continuous and exceptionally high demand for energy, which is met
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Prof. Dr. Peter Rehling, director of the Institute for Cell Biochemistry, UMG. Photo: MBExC

21.08.2026

Peter Rehling Elected to the Polish Academy of Sciences

The Polish Academy of Sciences has elected new foreign members. MBExC member Prof. Dr. Peter Rehling, director of the Institute for Cell Biochemistry at the University Medical Center Göttingen (UMG), will become a new member of Division II for Biological and Agricultural Sciences. Membership in the Polish Academy of Sciences
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18.08.2026

Dielectric Interfaces Reshape Dynamic Single-Molecule Optical Fingerprints in Nanoscopic Polymer Films

Authors Marx D, Malsbenden D, Gligonov I, Wöll D, Enderlein J, Nevskyi O Journal ChemRxiv Citation ChemRxiv. 18 August 2026. Abstract Fluorescence lifetimes near dielectric interfaces depend on molecular dipole orientation, but this relationship becomes more complex when emitters are confined within finite nanoscopic films. Here, we combine radially polarized
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14.08.2026

Adaptation of OXPHOS biogenesis to cellular requirements

Authors Dennerlein S, Rehling P Journal Protein Science Citation Protein Sci. 2026 Sep;35(9):e70763. Abstract Metabolic cues regulate the formation of the mitochondrial OXPHOS machinery. These regulatory processes are tightly linked to mitochondrial translation, proteolytic degradation of unassembled subunits, and the formation of supercomplexes, creating checkpoints at which nutrient availability, oxygen
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11.08.2026

Optimizing infectious disease mitigation under dynamic conditions

Authors Müller L, Sartori F, Dehning J, Eggl MF, Priesemann V Journal Proceedings of the National Academy of Sciences of the USA Citation Proc Natl Acad Sci U S A. 2026 Aug 11;123(32):e2527395123. Abstract Mitigation measures are essential for controlling the spread of infectious diseases during pandemics and epidemics, but
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11.08.2026

ONE microscopy

Authors Shaib AH, Alawieh MM, Rizzoli SO Journal Nature Protocols Citation Nat Protoc. 2026 Aug 11. Abstract The introduction of expansion microscopy (ExM), a decade ago, marked a shift in super-resolution imaging, by physically separating fluorophores to bypass the diffraction limit. Numerous ExM developments have extended the method’s reach since,
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Many snapshots of the cancer protein p53, superimposed on top of one another and color-coded, illustrate the complex motion patterns of this intrinsically disordered protein. Some of the transient structural elements appear as “helix-like structures”. © Dániel Szöllősi / MPI-NAT

10.08.2026

Cancer protein p53 observed in action: more order than expected

Cancer occurs when cells divide uncontrollably and displace healthy cells. Tumor suppressors provide an important defense against this. As molecular growth inhibitors, they prevent healthy cells from becoming cancerous. A key protein among them is p53, also known as the “guardian of the genome”. If p53 detects errors in a
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