2026 – MBExC

19.09.2026

Lysosomal signaling pathways influence heart rhythm, and regulate atrial function

Authors Akerman E, Capel RA, Rog-Zielinska EA, Winbo A, Aston D, Falter F, Bin Abdul Mu-U-Min R, Read MJ, Bose SJ, Swietach P, Wang J, Corbett AD, Koschinski A, Calamaio S, Melgari D, Prevostini R, Rivolta I, Ayagama T, Jenkin I, Simon JN, Fakuade FE, Pronto JR, Sharma P, Melia

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17.09.2026

All-optical closed-loop control of human cardiomyocyte networks exploiting holographic optogenetics

Authors Bögershausen N, Yigit G, Fedorenko A, Bayati R, Döring P, Gerhardt M, Strohmeyer C, Gutiérrez-Gutiérrez O, Javanmardi B, Gaubert M, Kaygusuz E, Krawitz P, Ueffing M, Hoerauf H, Feltgen N, Michalakis S, Büning H, Cyganek L, Wollnik B Journal Communications Engineering Citation Commun Eng. 2026 Sep 17;5(1):159. Abstract Heart

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17.09.2026

AMPK reinforces mitochondrial metabolism and suppresses pathological remodeling in Complex V-deficient cardiomyocytes

Authors Palacios-Contreras E, an der Brugge K, Fell J, Stephan T, Amedei H, Lenz C, Pesek J, Taudte VR, Lange F, Jakobs S, Sossalla S, Zelarayan LC, Cabrera-Orefice A, Cyganek L, Pavez-Giani MG Journal BioRxiv Citation bioRxiv 2026.09.14.751384. Abstract TMEM70 variants represent the most common nuclear cause of mitochondrial ATP

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16.09.2026

New building for hearing research

The University Medical Center Göttingen (UMG) is constructing a new research building for the Institute for Auditory Neuroscience (IAN). By the end of 2028, laboratories, offices, and spaces for scientific exchange will be completed across more than 1,800 square meters. In the new building, researchers will collaborate with the research

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14.09.2026

InsightRP2-An Interdisciplinary Approach Toward Therapy Development in RP2-Associated Retinopathy

Authors Bögershausen N, Yigit G, Fedorenko A, Bayati R, Döring P, Gerhardt M, Strohmeyer C, Gutiérrez-Gutiérrez O, Javanmardi B, Gaubert M, Kaygusuz E, Krawitz P, Ueffing M, Hoerauf H, Feltgen N, Michalakis S, Büning H, Cyganek L, Wollnik B Journal Human Gene Therapy Citation Hum Gene Ther. 2026 Sep 14:10430342261480906.

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11.09.2026

MBExC Application Specialist Position for Dr. Mette Handberg-Thorsager

The MBExC cordially welcomes Dr. Mette Handberg-Thorsager, who started her position as Application Specialist for Multiscale Biology on 15th July 2026. Her research will focus on “how genes, cells, and biophysical mechanisms interact to shape the animal body plan, particularly in marine invertebrates”. Her Application Specialist fellow position is affiliated

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10.09.2026

Nx3 Is a Z-Disk Structural and Signaling Hub That Is Reduced in Heart Failure

Authors Linke WA, Kümper L, Fomin A, Martin I, Ignatyeva N, Hashimoto K, Mohr C, Bässler J, Gärtner A, Ohira M, Hanashima A, Klotz A, Schiffer K, Voelkel T, Freundt JK, Hucke A, Koser F, Zhang T, Hobbach AJ, Glass IA; Birth Defects Research Laboratory; Gummert JF, Dos Remedios CG,

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10.09.2026

Gromov-Wasserstein Barycenter Surrogates: Statistical Methodology, Distributional Limits and Applications

Authors Steinkamp F, Rodríguez LA, Otte JV, Munk A Journal Arxiv Citation arXiv:2609.11670. Abstract We introduce statistical theory for the matching of finitely many objects, represented as metric measure spaces (mm-spaces). The approach is based on the second lower bound (SLB) of the Gromov-Wasserstein distance and thus is able to

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10.09.2026

Structure of the human mitochondrial RNA degradosome reveals a distinct mode of helicase-nuclease coupling

Authors do Prado PFV, Sharma S, Bhatta A, Vuckovic A, Parvizian Marani M, Llarena David AP, Kuhle B, Hillen HS Journal BioRxiv Citation bioRxiv 2026.09.06.749684. Abstract RNA degradation shapes cellular and organellar gene expression. In human mitochondria, this process is mediated by a dedicated degradosome comprising the helicase SUV3 and

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09.09.2026

Guanosine 10 methylation by TRMT11-TRMT112 optimizes human mitochondrial tRNAs for efficient translation

Authors Petrosyan J, Yilmaz M, Scheitl CPM, Lemus-Diaz N, Boshnakovska A, Tay LLE, Hu W, Beine-Golovchuk O, Touboul D, Richter-Dennerlein R, Höbartner C, Graille M, Rehling P, Bohnsack KE Journal Nucleic Acids Research Citation Nucleic Acids Res. 2026 Aug 24;54(16):gkag859. Abstract Modified nucleotides are essential determinants of RNA function, and

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