02.03.2024
First heat map for individual red blood cells
Researchers measure heat flow: from active metabolic forces inside cell to flickering cell membrane Entropy is often associated with disorder and chaos, but in biology it is related to energy efficiency and is closely linked to metabolism, the set of chemical reactions that sustain life. An international research team
01.03.2024
Light into the darkness of photosynthesis: 3D insights into the copying machine of chloroplasts
For life on Earth, it is essential that plants carry out photosynthesis and ultimately produce oxygen and chemical energy with the help of sunlight. Researchers from Göttingen and Hannover have now succeeded for the first time in visualizing the copying machine of chloroplasts, the RNA polymerase PEP, in high-resolution 3D.
01.03.2024
Lipid fibrils: A new building block for understanding Alzheimer’s disease
Lipids play an important role in the development of Alzheimer’s dementia. However, more details about this process were previously unknown. A team of scientists from Göttingen, Jülich, and Düsseldorf has now determined the atomic structures of lipid-fibril complexes for the first time. Link to the press release article (in
08.02.2024
Recordings of Public Lecture Series “Herz und Hirn gemeinsam im Fokus” online
„Herz und Hirn gemeinsam im Fokus“ (Heart and Brain in focus together) is the title of the public lecture series of the University of Göttingen and the Lower Saxony Academy of Sciences and Humanities in Göttingen in the winter semester 2023/2024. In the series, MBExC scientists gave comprehensive insights into
01.02.2024
New gene therapy for children born deaf in clinical trials
To date, hearing impairment can only be treated with medical devices such as hearing aids or cochlear implants. Gene therapy could offer an alternative in certain cases in the future. Building on pioneering work by researchers at the University Medical Center Göttingen (UMG), children suffering from a hearing impairment due
19.01.2024
Energy supply in human cells is subject to quality control
Researchers at the University Medical Center Göttingen (UMG) and members of the MBExC have discovered a new quality control mechanism that regulates the energy production in human cells. This process takes place in mitochondria, the power plants of the cell. Malfunctions of mitochondria lead to serious diseases of the nerves,
21.12.2023
Big impacts from small changes in cell
Research at Göttingen and Warwick Universities reveals how filament interactions affect cellular networks Tiny things matter – for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Göttingen and Warwick investigated the structure and mechanics of the main component of the
14.12.2023
New insights into sound coding in our ears
Sensory cells and neurons in the ear communicate by secreting neurotransmitter in response to sound stimuli. Scientists of the University Medical Center Göttingen, the Cluster of Excellence Multiscale Bioimaging, and the Max Planck Institute for Multidisciplinary Sciences describe new details of this process that regulates the release of neurotransmitters and
05.12.2023
Detecting side effects of new drugs on the heart more efficiently
Scientists at the University Medical Center and the University of Göttingen have developed a novel method to predict the side effects of new drugs and therapeutic approaches on the heart more efficiently. The advantage: this method is already effective in a very early test phase, even before preclinical screening in
06.11.2023
Protein stock for the beginning of a new life
How mysterious structures in the egg cell supply the early embryo as protein storage sites When mammals have offspring, they invest a lot. Unlike fish or frogs, the embryo cannot develop on its own. It has to implant in the uterus, where it is supplied with everything it needs