Lipids play an important role in the development of Alzheimer’s dementia. However, more details about this process were previously unknown. A team of scientists from Göttingen, Jülich, and Düsseldorf has now determined the atomic structures of lipid-fibril complexes for the first time.
3D reconstruction of an amyloid-β peptide (in yellow) and lipids attached around it (in blue), calculated from cryo-electron microscopy images. Gunnar Schröder / Research Centre Jülich, HHU Düsseldorf
