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21.04.2024

Myosin II actively regulates Drosophila proprioceptors

Authors Guan C, Nishi K, Kreis CT, Baeumchen O, Goepfert MC, Schmidt CF Journal BioRxiv Citation bioRxiv 2024.04.18.590050. Abstract Auditory receptors can be motile to actively amplify their mechanical input. Here we describe a novel and different type of motility that, residing in supporting cells, shapes physiological responses of mechanoreceptor
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18.04.2024

Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment

Authors Weigel M, Dechent P, Galbusera R, Bahn E, Lu PJ, Kappos L, Brueck W, Stadelmann C, Granziera C Journal BioRxiv Citation bioRxiv 2024.04.18.589707. Abstract Background: Ultra-high-resolution magnetic resonance imaging of the ex vivo brain is increasingly becoming an indispensable tool for studying the morphology and potential pathology of the
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04.04.2024

Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT

Authors Oleksiievets N, Mougios N, Jans DC, Hauke L, Thiele JC, Basak S, Jakobs S, Opazo F, Enderlein J, Tsukanov R, Sananbenesi F, Fischer A   Journal BioRxiv   Citation bioRxiv 2024.04.02.587536.   Abstract DNA-points accumulation for imaging in nanoscale topography (DNA-PAINT) is a potent variant of single-molecule localization microscopy
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10.03.2024

Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies

Authors Sridhar S, Vystrčilová M, Khani MH, Karamanlis D, Schreyer HM, Ramakrishna V, Krüppel S, Zapp SJ, Mietsch M, Ecker A, Gollisch T Journal BioRxiv Citation bioRxiv 2024.03.05.583449. Abstract Retinal ganglion cells, the output neurons of the vertebrate retina, often display nonlinear summation of visual signals over their receptive fields.
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09.03.2024

Convolutional neural network models of the primate retina reveal adaptation to natural stimulus statistics

Authors Vystrčilová M, Sridhar S, Burg MF, Gollisch T, Ecker AS Journal BioRxiv Citation bioRxiv 2024.03.06.583740. Abstract The diverse nature of visual environments demands that the retina, the first stage of the visual system, encodes a vast range of stimuli with various statistics. The retina adapts its computations to some
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08.03.2024

Synphilin-1 as a modulator of aSyn assembly

Authors Lázaro DF, Amen T, Gerhardt E, Santos PI, Milovanovic D, Höglinger G, Outeiro TF Journal BioRxiv Citation bioRxiv 2024.03.05.583522. Abstract Alpha-synuclein (aSyn) is an intrinsically disordered protein that undergoes phase-separation and is associated with several neurodegenerative conditions. However, the function and the pathological role of aSyn are still elusive.
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16.02.2024

Near-optimal information relay by the neuronal population of layer 4 barrel cortex

Authors Revah O, Wolf F, Gutnick MJ, Neef A Journal BioRxiv Citation bioRxiv 2024.02.15.580451. Abstract Cortical function reflects the coordinated activities of populations of neurons, which, in turn, depend on the speed with which each neuron can respond to input, as revealed by dynamic gain analysis. In Layer 4 of
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02.01.2024

Thermogenetics for cardiac pacing

Authors Balatskiy AV, Nesterenko AM, Lanin AA, Ovechkina VS, Sabinin SS, Fetisova ES, Moshchenko AA, Jappy D, Sokolov RA, Biglova DZ, Solius GM, Solyus EM, Korolev SV, Podgorny OV, Kelmanson IV, Rozov AV, Fedotov AB, Bruegmann T, Zheltikov AM, Mozhaev AA, Belousov VV Journal BioRxiv Citation bioRxiv 2024.01.02.573885. Abstract Cardiac
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28.11.2023

Structure and dynamics of human cardiac fibroblast nanotubes

Authors Schmid-Herbstritt SC, Stief G, Greiner J, Felekary A, Madl J, Zeidler V, Heer J, Iaconianni P, Koch M, Kollmar K, Walz C, Nubling S, Kok T, Pronto JR, Kutschka I, Voigt N, Morgan G, Dienert J, Brox T, Briquez P, Peyronnet R, Rohrbach A, Kohl P, Rog-Zielinska EA Journal
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17.11.2023

Prediction mismatch responses arise as corrections of a predictive spiking code

Authors van Driel K, Rudelt L, Priesemann V, Mikulasch FA Journal Biorxiv Citation bioRxiv 2023.11.16.567335. Abstract Prediction mismatch responses in cortex seem to signal the difference between an internal model of the animal and sensory observations. Often these responses are interpreted as evidence for the existence of error neurons, which
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