Research Alliance

Home >> Publications >> Research Alliance >> Page 2
Feature image not available
07.10.2025

Mapping complex optical light field distributions with single fluorescent molecules

Authors Marx D, Gligonov I, Malsbenden D, Wöll D, Nevskyi O, Enderlein J Journal Arxiv Citation arXiv:2510.05791. Abstract Single fluorescent molecules, behaving as ideal electric dipole emitters, are powerful nanoscopic probes of complex optical fields. Here, this property is exploited to precisely map the polarization and vectorial structure of tightly
Learn More
Feature image not available
07.10.2025

A versatile microfluidics platform for enhanced multi-target super-resolution microscopy

Authors Basak S, Chi-Vu K, Mougios N, Oleksiievets N, Pollack Y, Brandenburg S, Opazo F, Lehnart SE, Enderlein J, Tsukanov R Journal BioRxiv Citation bioRxiv 2025.10.07.680900. Abstract DNA-based Point Accumulation for Imaging in Nanoscale Topography (DNA-PAINT) is a powerful variant of single-molecule localization microscopy (SMLM) that overcomes the limitations of
Learn More
Feature image not available
06.10.2025

Transient Non-local Interactions Dominate the Dynamics of Measles Virus NTAIL

Authors Otteson L, Nagy G, Kunkel J, Kodis G, Bock LV, Bignon C, Longhi S, Zheng W, Grubmüller H, Vaiana AC, Vaiana SM Journal Communications Chemistry Citation Commun Chem. 2025 Oct 6;8(1):298. Abstract The RNA genome of measles virus is encapsidated by the nucleoprotein within a helical nucleocapsid that serves
Learn More
Feature image not available
06.10.2025

Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress

Authors Ehses K, López-Alonso JP, Antico O, Azem A, Muqit MMK, Ubarretxena-Belandia I, Fernández-Busnadiego R Journal BioRxiv Citation bioRxiv 2025.10.06.680693. Abstract Cells have evolved organelle-specific responses to maintain protein homeostasis (proteostasis). During proteostatic stress, mitochondria downregulate translation and enhance protein folding, yet the underlying mechanisms remain poorly defined. Here, we
Learn More
Feature image not available
06.10.2025

Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early-Onset Parkinsonism

Authors Dafsari HS, Deneubourg C, Singh K, Maroofian R, Suprenant Z, Kho AL, Ingham NJ, Steel KP, Sheshadri P, Baur F, Hentrich L, Gerisch B, Zamani M, Alves C, Siddiqui A, Dafsari HS, Salari M, Lang AE, Harris M, Abdelaleem A, Sadeghian S, Azizimalamiri R, Galehdari H, Shariati G, Sedaghat
Learn More
Feature image not available
01.10.2025

Active intracellular mechanics – a key to cellular function and organization

Authors Eskandari MA, Fischer J, Veyret N, Marx D, Betz T Journal Journal of Cell Science Citation J Cell Sci. 2025 Oct 1;138(19):jcs263874. Abstract Mechanobiology has demonstrated that precise control over mechanical properties at the whole-cell level is crucial for many biological functions. However, comparatively little attention has been paid
Learn More
Feature image not available
01.10.2025

3D histology of human heart-forming organoids by X-ray phase-contrast tomography

Authors Komorowski K, Reichmann J, Drakhlis L, Zweigerdt R, Salditt T Journal Communications Biology Citation Commun Biol. 2025 Oct 1;8(1):1411. Abstract Three-dimensional (3D) imaging is crucial for elucidating the complex structure of organoid models which involve complex spatial cellular and tissue organization in 3D. While a variety of volume imaging
Learn More
Feature image not available
01.10.2025

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale X-ray phase-contrast tomography

Authors Franz J, Reichmann J, Eckermann M, Würfel T, Groh A, Qadri SF, Schulz K, Mollenhauer B, Stadelmann C, Salditt T   Journal Brain Pathology   Citation Brain Pathol. 2025 Oct 1:e70044.   Abstract This study leverages x-ray phase-contrast tomography (XPCT) for detailed analysis of neurodegenerative diseases, focusing on the
Learn More
Feature image not available
30.09.2025

Pharmacological inhibition of V-ATPase targets mode-switching but not the proton transport cycle

Authors Kosmidis E, Fokaeos M, Shuttle CG, Isselstein MC, Cvjetkovic A, Johnson PJ, Pederesen JL, Jahn R, Preobraschenski J, Stamou D Journal BioRxiv Citation bioRxiv 2025.09.28.679038. Abstract Vacuolar-type adenosine triphosphatases (V-ATPases) are rotary proton pumps that establish proton gradients across cellular membranes. Their pharmacological inhibition is currently under active investigation
Learn More
Feature image not available
29.09.2025

International expert consensus on gene therapy for hereditary hearing loss: based on clinical trials

Authors Fan X, Gao Z, Zhong J, Chen Y, Chen X, Landegger LD, Moser T, Zeng FG, Sun Y, Jin X, Nash R, Chien WW, Jiang D, Greinwald JH, Bance M, Rodriguez MM, Lee SY, Feng G, Yang H, Wu CC, Xu L, Yuan W, Feng Y, Zhao Y, Vona
Learn More
X
EN DE
X
X