Research Alliance

Authors Reichmann J, Schnurpfeil A, Mittelstädt S, Jensen PM, Dahl VA Dahl AB, Weide C, von Campenhausen E, Dejea H, Tafforeau P, Werlein C, Jonigk D, Ackermann M, Engel K, Gallwas J, Dietz A, Hasanov MF, Salditt T Journal PNAS Nexus Citation PNAS Nexus, Volume 4, Issue 1, January 2025,

Authors Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K, Bohnsack KE, Hillen H Journal Nature Structural & Molecular Biology Citation Nat Struct Mol Biol (2025). Abstract Eukaryotic transfer RNA (tRNA) precursors undergo sequential processing steps to become mature tRNAs. In humans, ELAC2 carries out 3′ end processing of

Authors Yousefi R, Cruz-Zaragoza LD, Valpadashi A, Hansohn C, Dahal D, Richter-Dennerlein R, Rizzoli S, Urlaub H, Rehling P, Pacheu-Grau D Journal Cell Reports Citation Cell Rep, 44, 115143. Abstract Mitochondrial DNA encodes 13 subunits of the oxidative phosphorylation (OXPHOS) system, which are synthesized inside the organelle and essential for

Authors Engelken R, Monteforte M, Wolf F   Journal Arxiv   Citation arXiv:2412.21188.   Abstract Nerve impulses, the currency of information flow in the brain, are generated by an instability of the neuronal membrane potential dynamics. Neuronal circuits exhibit collective chaos that appears essential for learning, memory, sensory processing, and

Authors Rajput M, Malik IA, Methi A, Cortés Silva JA, Fey D, Wirths O, Fischer A, Wilting J, von Arnim CAF Journal Brain, Behavior, and Immunity Citation Brain Behav Immun. 2024 Dec 25:S0889-1591(24)00883-3. Abstract Obesity, a pandemic, worldwide afflicts almost one billion people. Obesity and ageing share several pathological pathways

Authors Jaime Tobón LM, Moser T Journal eLife Citation Elife. 2024 Dec 24;12:RP93749. Abstract Neural diversity can expand the encoding capacity of a circuitry. A striking example of diverse structure and function is presented by the afferent synapses between inner hair cells (IHCs) and spiral ganglion neurons (SGNs) in the

Authors Oestreicher D, Chepurwar S, Kusch K, Rankovic V, Jung S, Strenzke N, Pangrsic T Journal eLife Citation Elife. 2024 Dec 24;13:RP93646. Abstract To encode continuous sound stimuli, the inner hair cell (IHC) ribbon synapses utilize calcium-binding proteins (CaBPs), which reduce the inactivation of their CaV1.3 calcium channels. Mutations in

Authors Blob A, Ventzke D, Rölleke U, Nies G, Munk A, Schaedel L, Köster S   Journal Soft Matter   Citation Soft Matter, 2025, 21, 641-651.   Abstract The eukaryotic cytoskeleton is an intricate network of three types of mechanically distinct biopolymers — actin filaments, microtubules and intermediate filaments (IFs).

Authors Alekseev A, Hunniford V, Zerche M, Jeschke, M, El May F, Vavakou A, Siegenthaler D, Hueser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband M, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T,

Authors Schmidt A, Hiemeyer P, Wolf F Journal Arxiv Citation arXiv:2305.13420. Abstract Distributions of neuronal activity within cortical circuits are often found to display highly skewed shapes with many neurons emitting action potentials at low or vanishing rates, while some are active at high rates. Theoretical studies were able to