2026

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20.01.2026

Mapping Optical Chirality with Single Fluorescent Molecules

Authors Marx D, Gligonov I, Malsbenden D, Wöll D, Nevskyi O, Enderlein J. Journal Nano Letters Citation Nano Lett. 2026 Jan 20. Abstract Single fluorescent molecules, acting as ideal point dipoles, offer a unique means to probe light-matter interactions at the nanoscale. Here, we exploit this property to map the
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16.01.2026

DNA-PAINT resolves E-cadherin-independent cross-junctional F-actin organization in Drosophila embryonic tissue

Authors Häring M, Zhang Y, Zhang N, Allgeyer ES, Richens JH, Sirinakis G, Lv Z, St Johnston D, Wolf F, Großhans J, Kong D Journal Biophysical Journal Citation Biophys J. 2026 Jan 16:S0006-3495(26)00041-X. Abstract Cell junction remodeling is central to epithelial morphogenesis and tissue rheology, and depends on the interplay
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13.01.2026

Establishing synthetic ribbon-type active zones in a heterologous expression system

Authors Kapoor R, Do TT, Schwenzer N, Petrovic A, Dresbach T, Lehnart SE, Fernández-Busnadiego R, Moser T Journal eLife Citation Elife. 2026 Jan 13;13:RP98254. Abstract Encoding of several sensory modalities into neural signals is mediated by ribbon synapses. The synaptic ribbon tethers synaptic vesicles at the presynaptic active zone (AZ)
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12.01.2026

Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes

Authors Haydar S, Bednarz R, Laurette P, Sobitov I, Díaz I Pedrosa N, Videm P, Lueneburg T, Kuß S, Lahm H, Dreßen M, Krane M, Schmidt C, Grüning BA, Voigt N, Streckfuss-Bömeke K, Gilsbach R Journal Nature Communications Citation Nat Commun. 2026 Jan 12;17(1):117. Abstract Cis-regulatory elements (CREs) are noncoding
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12.01.2026

Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies

Authors Di Donato N; NMA Consortium; Thom A, Rump A, Greve JN, Cadiñanos J, Calabro S, Cathey S, Chung B, Cope H, Costales M, Cuvertino S, Dinkel P, Erripi K, Fry AE, Garavelli L, Hoffjan S, Janzarik WG, Kreimer I, Mancini G, Marin-Reina P, Meinhardt A, Niehaus I, Pilz D,
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09.01.2026

Restoring Shugoshin 1 reduces chromosome errors in human eggs

Authors Schuh M, Saha D, Manshaei S, Cavazza T, Holubcova S, Maierova B, Zielinska AP, Wartosch L, Blaney M, Elder K Journal BioRxiv Citation bioRxiv 2026.01.08.698387. Abstract Aneuploidy in human eggs, which rises sharply with age, is a leading cause of infertility, IVF failure, and miscarriage. This age-related aneuploidy is
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05.01.2026

Quick Adaptive Ternary Segmentation: An Efficient Decoding Procedure For Hidden Markov Models

Authors Mösching A, Li H, Munk A Journal Journal of Computational and Graphical Statistics Citation Journal of Computational and Graphical Statistics, 1–15. Abstract Hidden Markov models (HMMs) are characterized by an unobservable Markov chain and an observable process—a noisy version of the hidden chain. Decoding the original signal from the
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01.01.2026

Versatile Microfluidics Platform for Enhanced Multitarget Super-Resolution Microscopy

Authors Basak S, Vu KC, Mougios N, Oleksiievets N, Pollack YG, Brandenburg S, Opazo F, Lehnart SE, Enderlein J, Tsukanov R Journal ACS Nano Citation ACS Nano. 2026 Jan 1. Abstract DNA-based Point Accumulation for Imaging in Nanoscale Topography (DNA-PAINT) is a powerful variant of single-molecule localization microscopy (SMLM) that
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