2026

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11.08.2026

Optimizing infectious disease mitigation under dynamic conditions

Authors Müller L, Sartori F, Dehning J, Eggl MF, Priesemann V Journal Proceedings of the National Academy of Sciences of the USA Citation Proc Natl Acad Sci U S A. 2026 Aug 11;123(32):e2527395123. Abstract Mitigation measures are essential for controlling the spread of infectious diseases during pandemics and epidemics, but
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11.08.2026

ONE microscopy

Authors Shaib AH, Alawieh MM, Rizzoli SO Journal Nature Protocols Citation Nat Protoc. 2026 Aug 11. Abstract The introduction of expansion microscopy (ExM), a decade ago, marked a shift in super-resolution imaging, by physically separating fluorophores to bypass the diffraction limit. Numerous ExM developments have extended the method’s reach since,
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06.08.2026

„Heart-in-the-dish“ models identify mechanisms of diastolic dysfunction

Authors Dittrich GM, Zimmermann WH. Journal Cell Stem Cell Citation Cell Stem Cell. 2026 Aug 6;33(8):1243-1245. Abstract Modeling of cardiac pathologies in tissue-engineered models is coming of age. Two independent studies by Reid et al.1 and Tani et al.2 present in-depth multi-phenomics data from a human cardiac organoid (hCO) model
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03.08.2026

A microfluidics platform for studying ion and solute transport by isolated synaptic vesicles

Authors Upmanyu N, Olsthoorn L, Leon S, Sambandan S, Perego E, Mimoso T, Socrier L, Cretich M, Chiari M, Steinem C, Köster S, Jahn R Journal Colloids and Surfaces B: Biointerfaces Citation Colloids Surf B Biointerfaces. 2026 Aug 3;268(Pt 2):116020. Abstract Loading of synaptic vesicles with neurotransmitters, an essential step
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31.07.2026

SGLT2 inhibition improves sarcomere contractile dysfunction in human models of dilated cardiomyopathy

Authors Plota D, Nosheen Saleem H, Lin KH, Wali R, Cheruiyot C, Münzel L, Hutschenreiter T, Tiburcy M, Meyer T, Habeck M, Wiedmann F, Schmidt C, Zimmermann WH, Ebert A Journal Journal of Translational Medicine Citation J Transl Med (2026). Abstract Background: Sodium–glucose cotransporter 2 inhibitors (SGLT2i) are now widely
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28.07.2026

Desmin Mutations Disrupt Filament Elongation and Drive Polymorphic Aggregation

Authors Schween L, Burchert JP, van der Heyden M, Schultheis D, Mücke N, Köster S, Strelkov SV, Herrmann H, Fabry B Journal BioRxiv Citation bioRxiv 2026.07.22.740046. Abstract In muscle cells, desmin intermediate filaments form a cytoskeletal network that maintains the structural integrity and mechanical coupling of myofibrils. Dominant missense mutations
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23.07.2026

Focal astrocyte loss reveals nuclear translocation during lesion repopulation

Authors Herwerth M, Wyss MT, Schmid NB, Lasne A, Condrau J, Ravotto L, Mateos Melero JM, Kaech A, Bredell G, Thomas C, Kim R, Kukanja P, Korobeynyk VL, Stadelmann C, Misgeld T, Bennett JL, Jessberger S, Saab AS, Liddelow SA, Weber B Journal Nature Neuroscience Citation Nat Neurosci. 2026 Jul
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19.07.2026

In silico framework for benchmarking optogenetic hearing restoration

Authors Khurana L, Nejedly P, Jagger DJ, Moser T, Jablonski L Journal BioRxiv Citation bioRxiv 2026.07.13.737798. Abstract Cochlear implants (CI) partially restore hearing in profoundly hearing impaired or deaf people by electrically stimulating the auditory nerve. A bottleneck of electrical CIs is the broad spread of electrical current from each
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17.07.2026

Structure and dynamics of the Nipah virus RNA-dependent RNA polymerase

Authors Sala FA, Hillen HS Journal Trends in Biochemical Sciences Citation Trends Biochem Sci. 2026 Jul 17:S0968-0004(26)00203-3. Abstract Nipah virus (NiV) is a highly pathogenic, nonsegmented, negative-sense RNA virus (nsNSV) from the Mononegavirales order that causes frequent outbreaks, with no approved treatment available. Replication and transcription of its genome are
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14.07.2026

RBM20 variants disrupt Ca2+ handling and metabolism in dilated and non-compaction cardiomyopathy stem cell models

Authors Rebs S, Sedaghat-Hamedani F, Kayvanpour E, Eberl H, Berečić B, Dudek J, Wagensohner N, Seedorf A, Unsöld JK, Hübscher D, Reich C, Klein T, Doose S, Nikolaev VO, Buchwald T, Wagdi A, Kohlhaas M, Dybkova N, Morais Costa P, Guan K, Hasenfuss G, Rog-Zielinska EA, Sossalla S, Sauer M,
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