Changes in DNA repair compartments and cohesin loss promote DNA damage accumulation in aged oocytes
Authors Sharma N, Coticchio G, Borini A, Tachibana K, Nasmyth KA, Schuh M Journal Current Biology Citation Curr Biol. 2024 Oct 17:S0960-9822(24)01281-8. Abstract Oocyte loss, a natural process that accelerates as women approach their mid-30s, poses a significant challenge to female reproduction. Recent studies have identified DNA damage as a