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Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factors

Authors Nadlera F, Lavdovskaiaa E, Richter-Dennerlein R Journal RNA Biology Citation RNA Biol. 2021 Dec 20;1-15. Abstract The universally conserved process of protein biosynthesis is crucial for maintaining cellular homoeostasis and in eukaryotes, mitochondrial translation is essential for aerobic energy production. Mitochondrial ribosomes (mitoribosomes) are highly specialized to synthesize 13
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Structural and functional insights into human tRNA guanine transgylcosylase

Authors Sievers K, Welp L, Urlaub H, Ficner R Journal RNA Biology Citation RNA Biol. 2021 Jul 31:1-15. Abstract The eukaryotic tRNA guanine transglycosylase (TGT) is an RNA modifying enzyme incorporating queuine, a hypermodified guanine derivative, into the tRNAsAsp,Asn,His,Tyr. While both subunits of the functional heterodimer have been crystallized individually,
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