Journal

Authors Hillen HS, Markov DA, Wojtas ID, Hofmann KB, Lidschreiber M, Cowan AT, Jones JL, Temiakov D, Cramer P, Anikin M Journal Proceedings of the National Academy of Sciences of the United States of America Citation PNAS, Apr 2021, 118 (15) e2009329118. Abstract Respiration-coupled ATP production yields most of the

Authors Aibara S, Schilbach S, Cramer P Journal Nature Citation Nature. 2021 Apr 26. Abstract The initiation of transcription is a focal point for the regulation of gene activity during mammalian cell differentiation and development. To initiate transcription, RNA polymerase II (Pol II) assembles with general transcription factors into a

Authors Hamann F, Zimmerningkat LC, Becker RA, Garbers TB, Neumann P, Hubc JS, Ficner R Journal Acta Crystallographica Section D-Structural Biology Citation Acta Cryst. (2021). D77, 496-509. Abstract Noncoding intron sequences present in precursor mRNAs need to be removed prior to translation, and they are excised via the spliceosome, a

Authors Hundrieser S, Klatt M, Munk A Journal ArXiv Citation arXiv:2103.15426. Abstract Empirical optimal transport (OT) plans and distances provide effective tools to compare and statistically match probability measures defined on a given ground space. Fundamental to this are distributional limit laws and we derive a central limit theorem for

Authors Tameling C, Stoldt S, Stephan T, Naas J, Jakobs S, Munk A Journal Nature Computational Science Citation Nat Comput Sci 1, 199–211 (2021). Abstract Super-resolution fluorescence microscopy is a widely used technique in cell biology. Stimulated emission depletion (STED) microscopy enables the recording of multiple-color images with subdiffraction resolution.

Authors Ulmke PA, Sakib MS, Ditte P, Sokpor G, Kerimoglu C, Pham L, Xie Y, Mao X, Rosenbusch J, Teichmann U, Nguyen HP, Fischer A, Eichele G, Staiger JF, Tuoc T Journal Stem Cell Reports Citation Stem Cell Reports. 2021 Mar 23:S2213-6711(21)00138-7. Abstract Intermediate progenitor cells (IPCs) are neocortical neuronal

Authors Krinner S, Predoehl F, Burfeind D, Vogl C, Moser T Journal Frontiers in Molecular Neuroscience Citation Front. Mol. Neurosci. 14:651935. Abstract The afferent synapses between inner hair cells (IHC) and spiral ganglion neurons are specialized to faithfully encode sound with sub-millisecond precision over prolonged periods of time. Here, we

Authors Keppeler D, Kampshoff C, Thirumalai A, Duque-Afonso CJ, Schaeper J, Quilitz T, Töpperwien M, Vogl C, Hessler R, Meyer A, Salditt T, Moser T Journal PNAS Citation PNAS May 4, 2021 118 (18) e2014472118. Abstract The cochlea of our auditory system is an intricate structure deeply embedded in the

Authors Wartosch L, Schindler K, Schuh M, Gruhn JR, Hoffmann ER, McCoy RC, Xing J Journal Prenatal Diagnosis Citation Prenatal Diagnosis. 2021;1–11. Abstract The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than

Authors Sahu B, Hartonen T, Pihlajamaa P, Wie B, Dave K, Zhu F, Kaasinen E, Lidschreiber K, Lidschreiber M, Daub CO, Cramer P, Kivioja T, Taipale J Journal bioRxiv Citation bioRxiv 2021.03.18.435942. Abstract DNA determines where and when genes are expressed, but the full set of sequence determinants that control