New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain
Authors Weninger G, Lehnart SE Journal Journal of Cellular Signaling Citation J Cell Signal. 2022;3(4):171-178. Abstract Junctophilin-2 (JP2) is a key structural protein of junctional membrane complexes (JMCs) that stabilize contacts between the sarcoplasmic reticulum and transverse tubules required for excitation-contraction (EC) coupling in cardiomyocytes. Under pathophysiological conditions, the intracellular
