Expanding our understanding of synucleinopathies: proteinopathy, proteinopenia, and lipidopathy
Authors Flores-León M, Outeiro TF Journal FEBS Journal Citation FEBS J. 2025 Feb 25. Abstract A possible consequence of the process of protein aggregation in neurodegenerative diseases is the depletion of soluble protein species (proteinopenia), which may, at least in some cases, reduce protein function/activity. This concept,