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25.09.2024

BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis

Authors Bergner CG, van der Meer F, Franz J, Vakrakou A, Würfel T, Nessler S, Schäfer L, Nau-Gietz C, Winkler A, Lagumersindez-Denis N, Wrzos C, Damkou IA, Sergiou C, Schultz V, Knauer C, Metz I, Bahn E, Rodriguez EG, Merkler D, Simons M, Stadelmann C Journal Brain Citation Brain. 2024
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10.11.2023

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders

Authors Kaiyrzhanov R, Rad A, Lin SJ, Bertoli-Avella A, Kallemeijn WW, Godwin A, Zaki MS, Huang K, Lau T, Petree C, Efthymiou S, Ghayoor Karimiani E, Hempel M, Normand EA, Rudnik-Schöneborn S, Schatz UA, Baggelaar MP, Ilyas M, Sultan T, Alvi JR, Ganieva M, Fowler B, Aanicai R, Akay Tayfun
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01.08.2023

Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies

Authors Chopra A, Outeiro TF Journal Brain Citation Brain. 2023 Aug 1:awad260. Abstract Parkinson’s disease is clinically known for the loss of dopaminergic neurons in the substantia nigra pars compacta and accumulation of intraneuronal cytoplasmic inclusions rich in alpha-synuclein called ‘Lewy bodies’ and ‘Lewy neurites’. Together with dementia with Lewy
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24.02.2022

A new form of axonal pathology in a spinal model of neuromyelitis optica

Authors Herwerth M, Kenet S, Schifferer M, Winkler A, Weber M, Snaidero N, Wang M, Lohrberg M, Bennett JL, Stadelmann C, Hemmer B, Misgeld T Journal Brain Citation Brain, 2022;, awac079. Abstract Neuromyelitis optica (NMO) is a chronic neuroinflammatory disease, which primarily targets astrocytes and often results in severe axon
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06.01.2022

Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

Authors Hatton C, Ghanem SS, Koss DJ, Abdi IY, Gibbons E, Guerreiro R, Bras J, International DLB Genetics Consortium, Walker L, Gelpi E, Heywood W, Outeiro TF, Attems J, McFarland R, Forsyth R, El-Agnaf OM, Erskine D Journal Brain Citation Brain. 2022 May 24;145(4):1257-1263. Abstract Krabbe disease is an infantile
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01.07.2020

Molecular signature of slowly expanding lesions in progressive multiple sclerosis

Authors Jäckle K, Zeis T, Schaeren-Wiemers N, Junker A, van der Meer F, Kramann N, Stadelmann C, Brück W Journal Brain Citation Brain. 2020 Jul 1;143(7):2073-2088. Abstract Multiple sclerosis is an immune-mediated chronic inflammatory disease of the CNS that leads to demyelinated lesions in the grey and white matter. Inflammatory,
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