Urlaub, Henning

Home >> Publications >> Author >> Urlaub, Henning
Feature image not available
19.08.2025

Proteo-transcriptomic reprogramming and resource reallocation define the aging mammalian brain

Authors Kumar NH, Kluever V, Kaufmann SV, Bergmann C, Mousaei K, Tomas M, Marrero MC, Chopra A, Hirose M, Pallas M, Sanfeliu C, Ibrahim SM, Fischer A, Outeiro TF, Urlaub H, Tchumatchenko T, Lopez Otin C, Fornasiero EF Journal BioRxiv Citation bioRxiv 2025.08.14.669896 Abstract Brain aging is a major risk
Learn More
Feature image not available
11.08.2025

Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry

Authors Welp LM, Wulf A, Chernev A, Horokhovskyi Y, Moshkovskii S, Dybkov O, Neumann P, Pašen M, Siraj A, Raabe M, Göthert H, Walshe JL, Infante DA, de A P Schwarzer AC, Dickmanns A, Johannsson S, Schmitzová J, Wohlgemuth I, Netz E, He Y, Fritzemeier K, Delanghe B, Viner R,
Learn More
Feature image not available
28.05.2025

Structural insights into lipid membrane binding by human ferlins

Authors Cretu C, Chernev A, Szabo CZK, Pena V, Urlaub H, Moser T, Preobraschenski J Journal EMBO Journal Citation EMBO J. 2025 May 28. Abstract Ferlins are ancient membrane proteins with a unique architecture, and play central roles in crucial processes that involve Ca2+-dependent vesicle fusion. Despite their links to
Learn More
Feature image not available
21.05.2025

SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart

Authors Boshnakovska A, Pronto JR, Gall T, Aich A, Prochazka J, Nichtova Z, Sedlacek R, Sobitov I, Ainatzi S, Lenz C, Katschinski DM, Urlaub H, Voigt N, Rehling P, Kremer LS Journal Cell Reports Citation Cell Reports, Volume 44, Issue 6, 115723. Abstract Mitochondria are key to cellular energetics, metabolism,
Learn More
Feature image not available
18.04.2025

Profiling the LAM family of contact site tethers provides insights into their regulation and function

Authors Fenech EJ, Kupervaser M, Boshnakovska A, Ravid S, Gomes Castro I, Asraf Y, Callegari S, Lenz C, Urlaub H, Rehling P, Schuldiner M Journal Contact (Thousand Oaks) Citation Contact (Thousand Oaks). 2025 Apr 17;8:25152564251321770. Abstract Membrane contact sites are molecular bridges between organelles that are sustained by tethering proteins
Learn More
Feature image not available
13.03.2025

Ca2+-triggered (de)ubiquitination events in synapses

Authors Ainatzi S, Kaufmann SV, Silbern I, Georgiev SV, Lorenz S, Rizzoli SO, Urlaub H Journal Molecular & Cellular Proteomics Citation Mol Cell Proteomics. 2025 Mar 13:100946. Abstract Neuronal communication relies on neurotransmitter release from synaptic vesicles (SVs), whose dynamics are controlled by Ca2+-dependent pathways, as many thoroughly studied phosphorylation
Learn More
Feature image not available
06.03.2025

Structural basis of Nipah virus RNA synthesis

Authors Sala FA, Ditter K, Dybkov O, Urlaub H, Hillen HS Journal Nature Communications Citation Nat Commun. 2025 Mar 6;16(1):2261. Abstract Nipah virus (NiV) is a non-segmented negative-strand RNA virus (nsNSV) with high pandemic potential, as it frequently causes zoonotic outbreaks and can be transmitted from human to human. Its
Learn More
Feature image not available
31.12.2024

A microscopy-based screen identifies cellular kinases modulating mitochondrial translation

Authors Yousefi R, Cruz-Zaragoza LD, Valpadashi A, Hansohn C, Dahal D, Richter-Dennerlein R, Rizzoli S, Urlaub H, Rehling P, Pacheu-Grau D Journal Cell Reports Citation Cell Rep, 44, 115143. Abstract Mitochondrial DNA encodes 13 subunits of the oxidative phosphorylation (OXPHOS) system, which are synthesized inside the organelle and essential for
Learn More
Feature image not available
24.10.2024

Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts

Authors Foo B, Amedei H, Kaur S, Jaawan S, Boshnakovska A, Gall T, de Boer RA, Silljé HHW, Urlaub H, Rehling P, Lenz C, Lehnart SE Journal PLoS One Citation PLoS One. 2024 Oct 24;19(10):e0311203. Abstract Phospholamban (PLN) is a sarco-endoplasmic reticulum (SER) membrane protein that regulates cardiac contraction/relaxation by
Learn More
Feature image not available
05.10.2024

The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling
Learn More
X
EN DE
X
X