Rizzoli, Silvio

Authors Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimolgu C, Wirths O, Bickeböller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka

Authors Sertel SM, Blumenstein W, Mandad S, Shomroni O, Salinas G, Rizzoli SO Journal Scientific Reports Citation Sci Rep. 2021 Aug 30;11(1):17374. Abstract A strong focus on sex-related differences has arisen recently in neurobiology, but most investigations focus on brain function in vivo, ignoring common experimental models like cultured neurons.

Authors Helm MS, Dankovich TM, Mandad S, Rammer B, Jähne S, Salimi V, Koerbs C, Leibrandt R, Urlaub H, Schikorski T, Rizzoli SO Journal Nature Neuroscience Citation Nat Neurosci (2021). Abstract Dendritic spines, the postsynaptic compartments of excitatory neurotransmission, have different shapes classified from ‘stubby’ to ‘mushroom-like’. Whereas mushroom spines

Authors Jähne S, Mikulasch F, Heuer HGH, Truckenbrodt S, Agüi-Gonzalez P, Grewe K, Vogts A, Rizzoli SO, Priesemann V Journal Cell Reports Citation Cell Reports 34, 108841, March 16, 2021. Abstract Synaptic transmission relies on the continual exocytosis and recycling of synaptic vesicles. Aged vesicle proteins are prevented from recycling

Authors Reshetniak S, Rizzoli SO Journal Current Opinion in Cell Biology Citation Curr Opin Cell Biol. 2021 Mar 8;71:63-68. Abstract For decades, the synaptic vesicle cluster has been thought of as a storage space for synaptic vesicles, whose obvious function is to provide vesicles for the depolarization-induced release of neurotransmitters;

Authors Yousefi R, Fornasiero EF, Cyganek L, Montoya J, Jakobs S, Rizzoli SO, Rehling P, Pacheu-Grau D Journal EMBO Reports Citation EMBO Rep. 2021 Feb 15:e51635. Abstract Mitochondria possess a small genome that codes for core subunits of the oxidative phosphorylation system and whose expression is essential for energy production.

Authors Silbern I, Pan KT, Fiosins M, Bonn S, Rizzoli SO, Fornasiero EF, Urlaub H, Jahn R Journal Molecular & Cellular Proteomics Citation Mol Cell Proteomics. 2021 Feb 11:100061. Abstract Synaptic transmission is mediated by the regulated exocytosis of synaptic vesicles. When the presynaptic membrane is depolarized by an incoming

Authors Sertel SM, von Elling-Tammen MS, Rizzoli SO Journal Journal of Neuroscience Citation J Neurosci. 2021 Feb 10;41(6):1157-1173. Abstract The activity and the metabolism of the brain change rhythmically during the day/night cycle. Such rhythmicity is also observed in cultured neurons from the suprachiasmatic nucleus, which is a critical center

Authors Dankovich TM, Rizzoli SO Journal iScience Citation iScience. 2021 Feb 3;24(3):102134. Abstract Optical super-resolution microscopy (SRM) has enabled biologists to visualize cellular structures with near-molecular resolution, giving unprecedented access to details about the amounts, sizes and spatial distributions of macromolecules in the cell. Precisely quantifying these molecular details requires

Authors Bonnin EA, Fornasiero EF, Lange F, Turck CW, Rizzoli SO Journal BMC Molecular and Cell Biology Citation BMC Mol and Cell Biol 22, 5 (2021). Abstract Background Most of the cells of the mammalian retina are terminally differentiated, and do not regenerate once fully developed. This implies that these